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DeSalvio Playground is a neighborhood park located on the corner of Spring Street and Mulberry Street in NoLita, in Manhattan, New York City.The playground has modular play equipment that is red, white, and green (in honor of the Italian flag), built-in stone chess tables, a basketball half-court, and benches.

Judson Health Center, founded in 1921, was an early New York City Community Health Center inspired by the Rev. Alonzo Ray Petty of the Baptist Judson Memorial Church located at 55 Washington Square South. Petty appealed to fellow Baptist and physician Eleanor A. Campbell to start the health and dental clinic, initially located in the church's basement, in order to provide care to the many Italian immigrants living on the west side of lower Manhattan. Many of these 45,000 residents suffered from poor nutrition; rickets was prevalent among many of the area's children. The health center quickly outgrew its space and in 1922 moved to Judson House at 237 Thompson Street. In 1924 the clinic provided healthcare to 22,000 visitors and also conducted 14,000 field visits, making the center the largest of its kind in the U.S. In 1950 the Center moved to 34 Spring Street and served residents living in the area bordered by Broadway, Washington Square and the Hudson River. The Center provided healthcare in over one million separate visits to residents and immigrants between 1921 and 1957, when Dr. Campbell was awarded the Star of Italian Solidarity by the Italian Government. Campbell, who refused any wages for her services throughout her lifetime, was born Eleanor Milbank Anderson, the daughter of philanthropist and public health advocate Elizabeth Milbank Anderson (1850-1921) and the artist Abraham Archibald Anderson (1846-1940). Judson Health Center continues to operate today at the Spring Street location under the auspices of the New York City Health and Hospitals Corporation.

Lombardi's is a pizzeria located at 32 Spring Street on the corner of Mott Street in the Nolita neighborhood in the borough of Manhattan, New York City. Opened in 1905, it has been recognized by the Pizza Hall of Fame as the first pizzeria in the United States.

The Ravenite Social Club was an Italian American heritage club at 247 Mulberry Street, in Little Italy, New York City. It was used as a mob hangout and the storefront later became a shoe store, and as of 2022 is a men's clothing store.

The Spring Street station is a local station on the IRT Lexington Avenue Line of the New York City Subway. Located at the intersection of Lafayette Street and Spring Street in SoHo and Little Italy, Manhattan, it is served by 6 trains at all times, <6> trains during weekdays in the peak direction, and 4 trains during late night hours. The Spring Street station was constructed for the Interborough Rapid Transit Company (IRT) as part of the city's first subway line, which was approved in 1900. Construction of the line segment that includes the Spring Street station started on September 12 of the same year. The station opened on October 27, 1904, as one of the original 28 stations of the New York City Subway. The station's platforms were lengthened in the late 1950s. The Spring Street station contains two side platforms and four tracks; express trains use the inner two tracks to bypass the station. The station was built with tile and mosaic decorations, which are continued along the platform extensions. The station contains exits to Spring Street at the center of each platform. The platforms are not connected to each other within fare control. The station contains elevators from the street, which make it compliant with the Americans with Disabilities Act of 1990.

Storefront for Art and Architecture is an independent, non-profit art and architecture organization located in SoHo, Manhattan in New York City. The organization is committed to the advancement of innovative positions in architecture, art and design.

Nolita, sometimes written as NoLIta, and deriving from "North of Little Italy" is a neighborhood in the borough of Manhattan in New York City. Nolita is situated in Lower Manhattan, bounded on the north by Houston Street, on the east by the Bowery, on the south roughly by Broome Street, and on the west by Lafayette Street. It lies east of SoHo, south of NoHo, west of the Lower East Side, and north of Little Italy and Chinatown.

St. Patrick's Old Cathedral School, at 32 Prince Street between Mulberry and Mott Streets in the Nolita neighborhood of Manhattan, New York City, was a Roman Catholic Pre-K through 8th grade school. It was one of the oldest schools in the Archdiocese of New York and in the city. It was founded by the Sisters of Charity and had a peak enrollment of approximately 500 students, Catholics and non-Catholics alike. The Federal-style building has been a New York City landmark since 1966 and, as part of the St. Patrick's Old Cathedral complex, was added to the National Register of Historic Places in 1977. It has been described as "the most significant institutional building in the Federal style surviving in New York City."The school closed in June 2010 due to low enrollment, and is slated to be turned into luxury townhouses, condominiums, and office space.

Lieutenant Joseph Petrosino Square is small triangular park in lower Manhattan in New York City, bounded by Cleveland Place and Lafayette and Kenmare Streets, two blocks north of the old police headquarters at 240 Centre Street, at the juncture of the Little Italy, Nolita, and SoHo neighborhoods. Formerly Kenmare Square, it changed its name in 1987 in honor of Lieutenant Joseph Petrosino, an early 20th century NYPD official dedicated to investigating and combating, among other adversaries, the Black Hand, an early version of the Mafia in America. The park underwent a $2 million renovation in 2008–2011, and is the site of a controversial CitiBike docking station.

Elizabeth Street Garden (ESG) is a 1-acre community sculpture garden in the Nolita neighborhood of Manhattan, New York City, located on Elizabeth Street between Prince and Spring Streets. The garden is managed by Elizabeth Street Garden, Inc. (ESG), a 501(c)(3) non-profit organization, and open to the public for general use and community events by ESG volunteers. City-owned and privately leased, the Garden is open to the public daily, weather permitting. Neighborhood volunteers operate the Garden year-round and program more than 200 free, public educational, wellness and arts-related events annually for children, seniors and all who live and work in the community.

The Chapel of San Lorenzo Ruiz was a Roman Catholic chapel in the Roman Catholic Archdiocese of New York, located at 378 Broome Street between Mulberry and Mott Streets in the Nolita neighborhood of Manhattan, New York City. The chapel was established in 2005. The building was originally constructed for the Church of the Most Holy Crucifix in 1925–26, and was designed by Robert J. Reiley.The chapel is designated for the Filipino Apostolate of the Archdiocese. It was named as the official "Church of Filipinos" by Archbishop Edward Cardinal Egan on June 15, 2005.

211 Elizabeth is a residential building at 211 Elizabeth Street, in the Nolita neighborhood of Manhattan. It was designed by architecture and interior design firm Roman and Williams and was the organization's first full building design. The building is primarily residential, but also includes space for three separate commercial developments on the first floor. It has fifteen units spread across seven stories, and room for three separate commercial developments in the structure's basement. Billy Joel and Gabriel Byrne are both residents of the building, as were Karlie Kloss and Josh Kushner until 2019.The bricks of the building were placed by hand, which is atypical for contemporary construction, as most buildings use pre-fabricated brick facades. Construction was led by Irish masons, and individual bricks cost up to $300 apiece. The building sold out in 2010, after failing to sell out when first placed on the market in 2008 due to the recession, a fact that resulted in a brief hiatus in listings. Tenants received a custom bike upon purchasing a residence. The building won a Palladio Award in 2010 for its use of traditional design and construction materials.