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Lieutenant Joseph Petrosino Square is small triangular park in lower Manhattan in New York City, bounded by Cleveland Place and Lafayette and Kenmare Streets, two blocks north of the old police headquarters at 240 Centre Street, at the juncture of the Little Italy, Nolita, and SoHo neighborhoods. Formerly Kenmare Square, it changed its name in 1987 in honor of Lieutenant Joseph Petrosino, an early 20th century NYPD official dedicated to investigating and combating, among other adversaries, the Black Hand, an early version of the Mafia in America. The park underwent a $2 million renovation in 2008–2011, and is the site of a controversial CitiBike docking station.

The Spring Street station is a local station on the IRT Lexington Avenue Line of the New York City Subway. Located at the intersection of Lafayette Street and Spring Street in SoHo and Little Italy, Manhattan, it is served by 6 trains at all times, <6> trains during weekdays in the peak direction, and 4 trains during late night hours. The Spring Street station was constructed for the Interborough Rapid Transit Company (IRT) as part of the city's first subway line, which was approved in 1900. Construction of the line segment that includes the Spring Street station started on September 12 of the same year. The station opened on October 27, 1904, as one of the original 28 stations of the New York City Subway. The station's platforms were lengthened in the late 1950s. The Spring Street station contains two side platforms and four tracks; express trains use the inner two tracks to bypass the station. The station was built with tile and mosaic decorations, which are continued along the platform extensions. The station contains exits to Spring Street at the center of each platform. The platforms are not connected to each other within fare control. The station contains elevators from the street, which make it compliant with the Americans with Disabilities Act of 1990.

DeSalvio Playground is a neighborhood park located on the corner of Spring Street and Mulberry Street in NoLita, in Manhattan, New York City.The playground has modular play equipment that is red, white, and green (in honor of the Italian flag), built-in stone chess tables, a basketball half-court, and benches.

Grotta Azzura, named for the Blue Grotto on the Isle of Capri is an Italian restaurant on the corner of Mulberry Street and Broome Street in the Little Italy section of the borough of Manhattan in New York City. The dining establishment was founded in 1908 by the Davino family and reopened in October 2003 in its original space after having been shut for six years. It is noted for having been a frequent haunt of Frank Sinatra and the Rat Pack as well as Enrico Caruso. In its later incarnation, it was a hangout for Heath Ledger, the young actor who spent some of his final days living in a rented loft space at 41 Broome street just down the street from the eatery.Grotta Azzura was one of the first places to serve "Lobster Fra Diavolo" (from the devil in Italian), an Italian American dish rather than a continental Italian one. Wine expert Victor Hazan and his wife the chef Marcella Hazan once told The New York Times that they first remembered eating it there circa 1940. Marcella went on to say "You brought me to that restaurant. I remember the dish clearly because it was so heavy and typical of Italian cooking in America. We don't eat like that in Italy".In 1977, a member of the restaurant's founding family, John Davino published a book of recipes associated with the establishment called The Recipes of the Grotta Azzurra.

Taïm is an Israeli restaurant located at 45 Spring Street (on the corner of Mulberry Street), in NoLita in Manhattan, New York City. "Taïm" means "tasty" in Hebrew.The Spring Street location opened in October 2012. Another location is at 222 Waverly Place (near Perry Street), in the West Village since 2005. There are now 7 other restaurant locations, including 2 restaurants in the Washington, DC area as well as a newly opened location in the Park Slope neighborhood of Brooklyn.

The Chapel of San Lorenzo Ruiz was a Roman Catholic chapel in the Roman Catholic Archdiocese of New York, located at 378 Broome Street between Mulberry and Mott Streets in the Nolita neighborhood of Manhattan, New York City. The chapel was established in 2005. The building was originally constructed for the Church of the Most Holy Crucifix in 1925–26, and was designed by Robert J. Reiley.The chapel is designated for the Filipino Apostolate of the Archdiocese. It was named as the official "Church of Filipinos" by Archbishop Edward Cardinal Egan on June 15, 2005.

Mulberry Street is a principal thoroughfare in Lower Manhattan, New York City. It is historically associated with Italian-American culture and history, and in the late 19th and early 20th centuries was the heart of Manhattan's Little Italy. The street was listed on maps of the area since at least 1755. The "Bend" in Mulberry, where the street changes direction from southeast to northwest to a northerly direction, was made to avoid the wetlands surrounding the Collect Pond. During the period of the American Revolution, Mulberry Street was usually referred to as "Slaughter-house Street", named for the slaughterhouse of Nicholas Bayard on what is now the southwest corner of Mulberry and Bayard Streets, which was located there until the summer of 1784, when it was ordered to be removed to Corlaer's Hook.Mulberry Bend, formed by Mulberry Street on the east and Orange Street on the west, was historically part of the core of the infamous Five Points; the southwest corner of Mulberry Bend formed part of the Five Points intersection for which the neighborhood was named. Aside from Mulberry, the other four streets forming Five Points were Anthony Street (now Worth Street), Cross Street (now Mosco Street), Orange Street (Baxter Street), and Little Water Street (which no longer exists).

Judson Health Center, founded in 1921, was an early New York City Community Health Center inspired by the Rev. Alonzo Ray Petty of the Baptist Judson Memorial Church located at 55 Washington Square South. Petty appealed to fellow Baptist and physician Eleanor A. Campbell to start the health and dental clinic, initially located in the church's basement, in order to provide care to the many Italian immigrants living on the west side of lower Manhattan. Many of these 45,000 residents suffered from poor nutrition; rickets was prevalent among many of the area's children. The health center quickly outgrew its space and in 1922 moved to Judson House at 237 Thompson Street. In 1924 the clinic provided healthcare to 22,000 visitors and also conducted 14,000 field visits, making the center the largest of its kind in the U.S. In 1950 the Center moved to 34 Spring Street and served residents living in the area bordered by Broadway, Washington Square and the Hudson River. The Center provided healthcare in over one million separate visits to residents and immigrants between 1921 and 1957, when Dr. Campbell was awarded the Star of Italian Solidarity by the Italian Government. Campbell, who refused any wages for her services throughout her lifetime, was born Eleanor Milbank Anderson, the daughter of philanthropist and public health advocate Elizabeth Milbank Anderson (1850-1921) and the artist Abraham Archibald Anderson (1846-1940). Judson Health Center continues to operate today at the Spring Street location under the auspices of the New York City Health and Hospitals Corporation.

Lombardi's is a pizzeria located at 32 Spring Street on the corner of Mott Street in the Nolita neighborhood in the borough of Manhattan, New York City. Opened in 1905, it has been recognized by the Pizza Hall of Fame as the first pizzeria in the United States.

Centre Market Place is a one block long street in Lower Manhattan, New York City, bordering Mulberry Street to the east, Grand Street to the south, Broome Street to the north, and Centre Street to the west. Centre Market Place was originally an extension of Orange Street (now Baxter Street, which starts at Grand Street, where Centre Market Place ends), before being formally renamed Centre Market Place in April 1837, after Centre Market, which was west of the street. At one time, the street was at the top of a high hill. Currently, local residents consider Centre Market Place to be part of the NoLIta neighborhood. At the southern end of the street, on the corner of Grand Street, is Onieal's restaurant, which features a cavernous wine cellar that once served as a speakeasy during Prohibition. Gentlemen of means would walk through the front of the Police Building, perhaps make a contribution to the "widows and orphan fund" and then walk through the cellar corridor connecting the two buildings.9 Centre Market Place was once the location to "The People's Bath House", a privately run public bathhouse built by the Association for Improving the Condition of the Poor. The People's Baths served as a model to which the City of New York would later build the city's truly public bathhouses. The block also included several gun stores including the John Jovino at 5 Centre Market Place, and the older Frank Lava Gunsmith at 6 Centre Market Place. The gun stores were part of a gun district owing to its proximity to the police headquarters at 240 Centre St. A row of townhouses at No. 1, 2, 4, and 5 were rehabilitated by two developers, a husband-and-wife team, incorporating found architectural castoffs scavenged from around the world as part of its facade.The street was home to many well-known writers, poets, and artists, including the noted crime photographer Weegee, who lived in a small studio apartment at 5 Centre Market Pl.

Soho Synagogue was a "hipster" synagogue located in the SoHo neighborhood of Manhattan, New York. On September 15, 2009, The SoHo Synagogue signed a 7-year lease for the ground floor of 43 Crosby Street, located between Spring and Broome Streets. Designer Dror Benshetrit designed the synagogue space.The SoHo Synagogue was founded in 2005 by Chabad-Lubavitch Rabbi Dovi Scheiner and his wife Esty.

Balthazar is a French brasserie restaurant located at 80 Spring Street (between Broadway and Crosby Street) in SoHo in Manhattan, in New York City. It opened on April 21, 1997, and is owned by restaurateur Keith McNally.: 182 McNally also owns Pastis, Cafe Luxembourg, Lucky Strike, the Russian-themed bar and restaurant Pravda, Odeon in Tribeca, and Schiller's Liquor Bar on the Lower East Side. Balthazar Bakery was later opened, at 80 Spring Street.McNally opened Balthazar in the theater district in Covent Garden in London, in February 2013. Balthazar London will reside within a building known as The Flower Cellars, sharing the space with The London Film Museum. The general manager will be Byron Lang.