Isaac Harmon Farmhouse

Robert Davis Farmhouse was a historic farmhouse located near Millsboro, Sussex County, Delaware. It was built about 1900, as a two-story, five-bay, single pile, wood-frame building with asbestos siding. It had a gable roof, with a cross gable and lancet window. Also on the property were two contributing log corn cribs.It was added to the National Register of Historic Places in 1979. It is listed on the Delaware Cultural and Historic Resources GIS system as destroyed or demolished.

Indian Mission School, also known as the Nanticoke Indian Center, is a historic school building located in Millsboro, Sussex County, Delaware. It was built in about 1948, after the original school was destroyed by fire. It is a one-story, stuccoed masonry building with a gable roof. It features a concrete block covered entrance. The school was organized after school reforms of the early 20th century mandated that the children of the strongly Native American families of the Nanticoke be placed in the same schools as African-American students.It was added to the National Register of Historic Places in 1979.

Harmon School, also known as Warwick No. 225, is a historic rural school building located near Millsboro, Sussex County, Delaware. It was built in the early 1920s, and is a one-story, frame structure with wood shingles in the Colonial Revival style. It sits on a concrete foundation and has a gable roof and large, square brick central chimney. The front facade features a central pedimented portico with four square columns and two square pilasters. The Harmon School was originally formed to be used exclusively for Nanticoke Indian students until after the new school was constructed in the 1920s. The introduction of African American teachers and students caused the Indian students to withdraw and form the Indian Mission School.It was added to the National Register of Historic Places in 1979.

Ames Hitchens Chicken Farm was a historic home and farm located near Millsboro, Sussex County, Delaware. It included a two-story, wood frame, gable front dwelling and two long, one-story, flatroofed buildings, used as chicken houses. It was the last of these structures still standing within the Indian River Nanticoke community.It was added to the National Register of Historic Places in 1979. It is listed on the Delaware Cultural and Historic Resources GIS system as destroyed or demolished.

Harmony Church is a historic Methodist Episcopal church located at Millsboro, Sussex County, Delaware. It was built in 1891, and is a one-story, wood-frame building covered with asbestos siding and in the Late Gothic Revival style. It has a two-story wing and sits on a rock-faced, concrete block foundation. It features a two-story crenellated tower. The congregation was organized in 1818. The Indian Mission Church was formed from Harmony Church after the hiring of an African American minister.It was added to the National Register of Historic Places in 1979.

Oak Orchard is an unincorporated community east of the town of Millsboro in Sussex County, Delaware, United States. Oak Orchard is bordered to the south by the Indian River Bay, to the east by Emily Gut (a narrow channel of water) and "the Peninsula", and to the north by Delaware Route 24. Oak Orchard is part of the Salisbury, Maryland-Delaware Metropolitan Statistical Area. This area has been the home of the Nanticoke Indian Tribe for over 2000 years and is home to the Nanticoke Indian Museum as well as a yearly Pow-wow held by the tribe. The unincorporated community is home to the Oak Orchard/Riverdale Post of the American Legion. Fire protection is provided by the Indian River Vol. Fire Co., ambulance service by the Mid-Sussex Rescue Squad, and police services are provided by the Delaware State Police as there is no incorporated town to provide such services. Oak Orchard was the scene of a house fire on January 3, 2001, that killed 11 family members.

Warwick is an unincorporated community in Sussex County, Delaware, United States. Warwick is located on Delaware Route 24, east of Millsboro and north of the Indian River.

Johnson School, also known as Warwick No. 203, is a historic rural school building located near Millsboro, Sussex County, Delaware. It was built in the early 1920s, and is a one-story, three-bay, frame structure with wood shingles in the Colonial Revival style. It has a gable roof and features a pedimented entrance portico supported by Doric order columns and plain pilasters. The Johnson School was a separate educational facility for African Americans, and was attended by some children whose families claimed Indian descent.It was added to the National Register of Historic Places in 1979.

Lingo Cove, Delaware is a 0.2 miles (0.32 km)-wide cove in Rehoboth Bay at the mouth of Herring Creek in Sussex County, Delaware.

Pepper Creek is a stream approximately 8 mi (13 km) long in southern Delaware in the United States. It rises in Cypress Swamp in southern Sussex County, approximately 3 mi (5 km) north of the Maryland state line. It flows generally east-northeast, past Dagsboro and into Indian River Bay, an inlet of the Atlantic Ocean, approximately 2 mi (3 km) northwest of Millville. The upper course of the creek is connected by channelized ditches through Cypress Swamp to the headwaters of the Pocomoke River.

The Indian River is a river and estuary, approximately 15 mi (24 km) long, in Sussex County in southern Delaware in the United States. The river is named after a Native American reservation that was located on its upper reaches. The Indian River rises approximately 2 miles (3.2 km) southwest of Georgetown and flows east, past Millsboro, its head of navigation. It enters Indian River Bay, an inlet of the Atlantic Ocean south of Cape Henlopen. The lower 6 miles (9.7 km) of the river form a navigable tidal estuary stretching westward from Indian River Bay, which is protected from the open ocean by two sand bar peninsulas. East of the bay is its mouth, the Indian River Inlet. Until 1928, the Indian River Inlet was a natural waterway that shifted up and down a two-mile (3.2 km) stretch of the coast. Dredging kept the inlet open in its current location between 1928 and 1937, and in 1938 the United States Army Corps of Engineers built jetties that hold it in place. Roads cross the river in three places, at U.S. Route 113 (in Millsboro), Delaware Route 24/Delaware Route 30 (also in Millsboro), and Delaware Route 1 (at Indian River Inlet in the Delaware Seashore State Park). With the Indian River Inlet in a fixed place beginning in 1928, it became possible to build a bridge to span it, and the completion of the Ocean Highway (present-day Delaware Route 1 and now known as Coastal Highway) between Rehoboth Beach and Bethany Beach in 1933 prompted Delaware to build a span to connect the northern and southern segments of the highway. Since 1934, six bridges have spanned the inlet, all known informally as the Indian River Inlet Bridge, although all but the first officially were named the Charles W. Cullen Bridge. The current Indian River Inlet Bridge opened in 2012.

Lingo Creek is a 1.7-mile-long (2.7 km) stream flowing southeast to Indian River Bay, 7.5 miles (12.1 km) northeast of Frankford in Sussex County, Delaware.