University of Detroit Mercy School of Law

Saints Peter and Paul Jesuit Church is a Roman Catholic church located at 629 East Jefferson Avenue in Detroit, Michigan. It is the oldest existing church in the city of Detroit, and was listed on the National Register of Historic Places and designated a Michigan State Historic Site in 1971.

The Charles Trombly House is located at 553 East Jefferson Avenue in Detroit, Michigan. It is more commonly known as the Beaubien House, and is currently the headquarters of the Michigan Architectural Foundation and the American Institute of Architects of Michigan. The building is one of the oldest remaining houses in Detroit, and was designated a Michigan State Historic Site in 1975 and listed on the National Register of Historic Places in 1979.

The Thomas A. Parker House was built as a private residence and is located at 975 East Jefferson Avenue in Detroit, Michigan. The house was listed on the National Register of Historic Places in 1982. It is currently the law offices of Liddle & Dubin, P.C.

The Blue Cross Blue Shield of Michigan Building is a skyscraper located at 600 East Lafayette Boulevard in Downtown Detroit, Michigan, near the Renaissance Center complex. It is also known as the Blue Cross Blue Shield Service Center. It was constructed in 1971, and stands at 22 floors. The building was constructed in a sunken plaza. It houses Blue Cross Blue Shield of Michigan. The campus in downtown Detroit also includes offices for 3,000 employees at Towers 500 and 600 of the Renaissance Center linked by the Detroit People Mover.

The Sibley House is a private residence located at 976 East Jefferson Avenue in Detroit, Michigan. It currently is used as the Rectory of Christ Church Detroit. The house was designated a Michigan State Historic Site in 1958 and listed on the National Register of Historic Places in 1971.

Christ Church Detroit is an Episcopal church located at 960 East Jefferson Avenue in Detroit, Michigan. It is also known as Old Christ Church, Detroit. It is the oldest Protestant church in Michigan still located on its original site. It was designated a Michigan State Historic Site in 1970 and listed on the National Register of Historic Places in 1971.

The Alexander Chapoton House is a Queen Anne style row house located at 511 Beaubien Street in Downtown Detroit, Michigan. It was listed on the National Register of Historic Places and designated a Michigan State Historic Site in 1980.

Renaissance Center station is a Detroit People Mover station in Downtown Detroit, Michigan. It is located at the northeast corner of the Renaissance Center complex (whence the station takes its name), connected to Tower 200 (Northwest) at Level 2 alongside Jefferson Avenue. As it serves RenCen, the station serves the Marriott Hotel, General Motors headquarters, the Riverfront and the Wintergarden shopping center. In 2014, this stop was the second most heavily trafficked (behind only Greektown) with 487,758 riders.The People Mover shut down temporarily on March 30, 2020, due to decreased ridership amid the COVID-19 pandemic. Following the system's May 2022 restart, the station reopened on September 14, 2022.

The Palms is an apartment building located at 1001 East Jefferson Avenue in Detroit, Michigan. It was one of the first buildings in the United States to use reinforced concrete as one of its major construction materials. It was listed on the National Register of Historic Places in 1985.

The Detroit Grand Prix (currently branded as the Chevrolet Detroit Grand Prix presented by Lear Corporation for sponsorship reasons) is an IndyCar Series race weekend held on a temporary circuit in Detroit, Michigan. The race has been held from 1989 to 2001, 2007 to 2008, and since 2012. Since 2012, the event has been scheduled for the weekend immediately following the Indianapolis 500. The origins of the event date back to the Formula One Detroit Grand Prix on the Detroit street circuit. The CART series began headlining the event in 1989, and in 1992, the race moved from downtown Detroit to Belle Isle, a park situated on an island in the Detroit River, which is the longest serving venue of the race. The IndyCar Series took over the race beginning in 2007. The race has been supported by Indy Lights and Formula Atlantic and top-level sports car series such as the Trans-Am Series and the ALMS. From 2023 the race returned to the downtown streets around the Renaissance Center using a circuit partially based on the original Detroit street circuit used by Formula One and CART. Open wheel racing in Detroit dates back to the 1920s–1950s, when AAA held the Detroit 100 at the Michigan State Fairgrounds Speedway. AAA also held one five-mile (8 km), non-championship race at Grosse Pointe in 1905. The Raceway on Belle Isle is classified as an FIA Grade Two circuit. The original Detroit Street Circuit was considered at the time an FIA Grade One circuit, while the downtown circuit is also an FIA Grade Two Circuit.

The streets of Detroit, in the U.S. state of Michigan, hosted Formula One racing, and later CART racing, between the 1982 and 1991 seasons. The street circuit (course) was set up near the Renaissance Center and the Cobo Arena, also including a small part of the M-1 highway, also known as Woodward Avenue. It is a flat circuit, with elevation ranging from 577–604 ft (176–184 m) above sea level. The circuit will be reopened in June 2023 for the IndyCar Detroit Grand Prix race with a modified and shortened layout.

Bricktown station is a Detroit People Mover station in Downtown Detroit, Michigan. It is located on Beaubien Street, just north of Congress Street. The station takes its name from the Bricktown Historic District. It also serves the nearby Wayne County Building and various restaurants and nightlife in the area. The People Mover shut down temporarily on March 30, 2020, due to decreased ridership amid the COVID-19 pandemic. Following the system's May 2022 restart, the station reopened on November 21, 2022.