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Ziggy's was a live music venue and bar in Winston-Salem, North Carolina. The venue in Baity Street closed after Thanksgiving in 2007. On August 5, 2011, Ziggy's reopened in Winston-Salem, in a 14,000 sq ft space on the corner of 8th and Trade St. in the Downtown Arts District. That venue closed down on February 21, 2016. It will reopen in 2022, where it will relocate to High Point. A former residence, Ziggy's became one of the premier club venues in the South. A wide variety of bands were hosted, with styles including Reggae, Rock, Blues, Hip Hop, and Country. Artists who have performed at Ziggy's include Thirty Seconds to Mars, Phish, Dave Matthews Band, The Black Crowes, Keller Williams, Slipknot, The Wailers, Andrew W.K., Perpetual Groove, Steel Pulse, Rusted Root, Jump Little Children, Ben Folds Five, Vertical Horizon, Hawthorne Heights, Emery, Anberlin, Mutemath, Insane Clown Posse, Twiztid, Lamb of God, Axe Murder Boyz, Blaze Ya Dead Homie, Mat Kearney, Turbonegro, and Saliva. In February 2003, Great White played at Ziggy's with their full pyrotechnic stage show mere days before the same effects would ignite the deadly fire that killed over 100 people at The Station nightclub in West Warwick, Rhode Island. In December 2004, Athenaeum played their final show on Ziggy's stage. Many great Misfit shows, Megadeth, Drain STH, and Danzig performed in the early years at the older location.

Lloyd Presbyterian Church is a historic African-American Presbyterian church located at 748 Chestnut Street in Winston-Salem, Forsyth County, North Carolina. It was built between 1900 and 1907, and is a gable-front, rectangular frame church in the Carpenter Gothic style. It is sheathed in weatherboard and features lancet windows and a small frame steeple, with a bellcast spire and ornamental sawn eave brackets along the top of the tower.It was listed on the National Register of Historic Places in 1998.

Craver Apartment Building is a historic apartment building located at Winston-Salem, Forsyth County, North Carolina. It was built about 1942, and is a two-story, five-bay, brick-veneered rectangular block structure with hipped roof and exposed rafter ends. It has a hipped roof and exposed rafter ends in the Bungalow / American Craftsman style. It features porches on both levels supported by full-height square brick posts. The building was built as rental apartments for African-American families just before World War II.It was listed on the National Register of Historic Places in 1998.

A. Robinson Building, also known as Howard-Robinson Building and Pyramid Barber Shop, is a historic commercial building located at Winston-Salem, Forsyth County, North Carolina. It was built in 1940–1941, and is a two-story, yellow and red brick commercial building. The north and south facades are of brick made by well-known and celebrated local brickmaker George S. Black. The building was constructed to house African-American businesses including the Howard-Robinson Funeral Home and a barber shop.It was listed on the National Register of Historic Places in 1998.

The Garage was a live music venue and bar in Winston-Salem, North Carolina, United States. It closed December 31, 2017. It was considered to be Winston's hallmark venue for local and touring acts. The Garage opened its doors unofficially in September 1999 and was owned and operated by Richard Emmett and Kimberly Lawson. The Garage was licensed and open in 2000. In May 2012, Emmett and Lawson sold the venue to its last owner, Tucker Tharpe. The Garage has been a host venue for Phuzz Phest, an annual music festival in downtown Winston-Salem, since 2012. The Garage has had two doormen Sam 'The Man' and Jon Hampton.

W.C. Brown Apartment Building was a historic apartment building located at Winston-Salem, Forsyth County, North Carolina. It was built about 1941, and was a two-story brick-veneered rectangular block structure. It had a hipped roof and exposed rafter ends in the Bungalow / American Craftsman style. The building was built as rental apartments for African-American families just before World War II. The building housed workers at the nearby R. J. Reynolds Tobacco Company. The building has been demolished. It was listed on the National Register of Historic Places in 1998.

Goler Memorial African Methodist Episcopal Zion Church, also known as Old Goler, is a historic African Methodist Episcopal Zion church located at 630 Patterson Avenue in Winston-Salem, Forsyth County, North Carolina. It was built in 1918–1919, and is a rectangular brick building in the Late Gothic Revival style. It features a gable-front block flanked by two square brick towers and stained glass windows. A two-story annex was built in 1946. In 1942, the Goler Metropolitan AME Zion Church congregation split from the Goler Memorial African Methodist Episcopal Zion Church.It was listed on the National Register of Historic Places in 1998.

The Career Center is a high school located in Winston-Salem, North Carolina. It offers an extension to the regular high school program. Classes offered include Advanced Placement courses, career and technical education (CTE) courses, English, and classes too small to be held at the regular high schools in the Winston-Salem/Forsyth County Schools program, such as Japanese and Chinese. It also offers extended day classes, which are held after school that allow students to "make up" a failed class in order to graduate. It moved to a new facility in January 2012 after a bond vote sold its previous facility to Forsyth Tech.

P.H. Hanes Knitting Company is a historic textile mill complex located at Winston-Salem, Forsyth County, North Carolina. The complex includes three buildings. The Knitting Building or North Building was built in 1920–1921, and is a six-story, Beaux-Arts style concrete and steel building sheathed in brick. The Mill Building or East Building was built in 1928, and is a five-story-plus-basement building of concrete, brick, and steel construction. The Warehouse and Shipping Building was built in 1940, and is a six-story steel frame building sheathed in brick. The P.H. Hanes Knitting Company was founded in 1901 by Pleasant H. Hanes, brother of John W. Hanes who founded Shamrock Mills, later Hanes Hosiery. In February 1965, P. H. Hanes Knitting Company merged with Hanes Hosiery. The downtown mill complex closed in 1965. The complex has been converted to loft apartments. It was listed on the National Register of Historic Places in 2005.

Downtown North Historic District, also known as Trade Street District, is a national historic district located at Winston-Salem, Forsyth County, North Carolina, USA. The district encompasses 46 contributing buildings in a commercial section of Winston-Salem. They were built between about 1907 and 1952, and most are one- or two-story brick buildings, sometimes with a stuccoed surface. Notable buildings include the Beaux-Arts style former United States Post Office (1914-1915, 1936-1937) with an addition by Northup and O'Brien, Brown-Rogers-Dixson Company Building (1928), Centenary Church Education Building (1920s), Pure Oil Station, City Market (1925), and Twin City Motor Company (1925).It was listed on the National Register of Historic Places in 2002.

Winston-Salem Tobacco Historic District is a national historic district located at Winston-Salem, Forsyth County, North Carolina. The district encompasses 16 contributing buildings and 16 contributing structures in a predominantly industrial section of Winston-Salem. The buildings date from about 1890 to 1959, and include buildings relating to the tobacco industry, specifically R. J. Reynolds Tobacco Company. Also on the district are a once-thriving African American and the wholesale commercial business district that once catered to the R. J. Reynolds Tobacco Company workers. Located in the district is the separately listed Romanesque Revival style S. J. Nissen Building and Piedmont Leaf Tobacco Company.It was listed on the National Register of Historic Places in 2009.

The RJR Plaza Building (also known as the Reynolds American Plaza Building) is a 16-story skyscraper in Winston-Salem, North Carolina which was completed in 1982 for R. J. Reynolds Tobacco Company, currently the second-largest tobacco manufacturer in the United States. In 2009, the RJR Plaza building became the headquarters for both Reynolds Tobacco and its parent company Reynolds American after Reynolds decided in 2008 to vacate its longtime headquarters, the Reynolds Building.The building, which has 449,150 square feet (41,726 square meters), was first planned in 1969 and would have been a pair of skyscrapers which would have been the tallest in the Southeastern United States. The FAA put an end to this plan. Hammill-Walter Associates served as the architect. The architectural style is Modernism, with a curtain wall facade and concrete rigid frame construction. A two-story galleria links this building and the Reynolds Building next door.