Gulf Tower

The Federal Reserve Bank of Cleveland Pittsburgh Branch Office is one of two Federal Reserve Bank of Cleveland branch offices (the other is in Cincinnati). The Pittsburgh Office of the Federal Reserve Bank of Cleveland hosts one of two savings bonds processing sites in the nation. The Pittsburgh branch presides over Jefferson, Monroe and Belmont counties in Ohio, Wetzel, Tyler, Pleasants, Marshall, Ohio, Brooke and Hancock counties in West Virginia, and all of Western Pennsylvania. In 1915 it was revealed that the Pittsburgh branch location was to be the new home of a relocated Cleveland Fed District with a majority vote secured on the board of governors, but the U.S. Attorney General at the time nixed moving the Cleveland, Kansas City, Minneapolis, Boston and Atlanta Federal Reserve Districts, stating that it would instead take an act of Congress to move those district headquarters. Pittsburgh remained a branch location only.

Koppers Building is a historical building in Pittsburgh, Pennsylvania, commissioned by Andrew W. Mellon and completed in 1929. The building is named after the Koppers Chemical Corporation and is one of the major features of Downtown Pittsburgh.

The August Wilson African American Cultural Center is a U.S. nonprofit arts organization based in Pittsburgh, Pennsylvania that presents performing and visual arts programs that celebrate the contributions of African Americans not only in Western Pennsylvania, but nationally and internationally. The August Wilson African American Cultural Center building is on Liberty Avenue in Downtown Pittsburgh's Cultural District. It includes galleries, classrooms, a 500-seat theater, a gift shop, a cafe, and many multi-purpose spaces for visual and performing art. The museum opened in 2009.

The University of Pittsburgh Medical Center (UPMC) is a $23 billion integrated global nonprofit health enterprise that has 92,000 employees, 40 hospitals with more than 8,000 licensed beds, 800 clinical locations including outpatient sites and doctors' offices, a 3.8 million-member health insurance division, as well as commercial and international ventures. It is closely affiliated with its academic partner, the University of Pittsburgh. It is considered a leading American health care provider, as its flagship facilities have ranked in U.S. News & World Report "Honor Roll" of the approximately 15 to 20 best hospitals in America for over 15 years. As of 2016, its flagship hospital UPMC Presbyterian is ranked 12th nationally among the best hospitals (and first in Pennsylvania) by U.S. News & World Report and ranked in 15 of 16 specialty areas when including UPMC Magee-Womens Hospital. This does not include UPMC Children's Hospital of Pittsburgh which ranked in the top 10 of pediatric centers in a separate US News ranking.

The Bell Telephone Building is a 339-foot (103 m) art deco skyscraper in Downtown Pittsburgh, Pennsylvania. It was completed in 1923 and has 20 floors. It is the 22nd-tallest building in the city.

The William S. Moorhead Federal Building is a 340-foot (100 m) tall skyscraper in downtown Pittsburgh, Pennsylvania, United States. Plans for the building were announced on November 9, 1958, and the structure was completed in 1964. It has 23 floors and is the 21st tallest building in Pittsburgh.

The Pennsylvania Canal Tunnel was the Pittsburgh terminus of the Pennsylvania Main Line of Public Works, a transportation system that involved other early tunnels. Construction was authorized February 8, 1827, and the tunnel was completed November 10, 1829. The canal crossed the Allegheny River on a covered bridge aqueduct, later replaced by John A. Roebling's first suspension bridge, the Allegheny Aqueduct., the canal traveled underground through most of downtown Pittsburgh, under Grant's Hill, to end in a lock leading to the Monongahela River. The original plan was to connect with the C&O canal at the Monongahela River, but that canal never reached its expected western end, and the tunnel's main use was to allow overflow from the canal to enter the Monongahela. Only one or two canal boats ever went through the tunnel and lock. The tunnel was made obsolete by the arrival of the Pennsylvania Railroad in 1852. The canal tunnel was uncovered during the construction of the U.S. Steel Tower in 1967, and later during the construction of the subway system, which used part of the tunnel on the south side.

The Joseph F. Weis, Jr. U.S. Courthouse is a Beaux Arts-style building in Pittsburgh, Pennsylvania, US. It is a courthouse for the Western District of Pennsylvania, a United States district court. Until 2015, the building was known as the US Post Office and Courthouse-Pittsburgh.

The U.S. Steel Tower, also known as the Steel Building or USX Tower (1988–2001), is a 64-story skyscraper at 600 Grant Street in downtown Pittsburgh, Pennsylvania. The interior has 2,300,000 sq ft (210,000 m2) of leasable space. Standing 841 ft (256 m) tall, it is the tallest building in Pittsburgh, the fifth-tallest in Pennsylvania, the 69th-tallest in the United States, and the 200th-tallest in the world. It held its opening dedication on September 30, 1971.The tower's original name when completed was the U.S. Steel Tower and was changed to USX Tower in 1988. The name was changed back to the U.S. Steel Tower in January 2002 to reflect U.S. Steel's new corporate identity (USX was the 1990s combined oil/energy/steel conglomerate). Although no longer the owner of the building, U.S. Steel remains one of the largest tenants.

The Allegheny HYP Club (Harvard-Yale-Princeton Club) is a private social club in downtown Pittsburgh, Pennsylvania. Located at 617-619 William Penn Place, it was built in 1894 and was added to the List of Pittsburgh History and Landmarks Foundation Historic Landmarks in 2002. On July 1, 1997, the club absorbed the Pittsburgh Club membership and assets.The Pittsburgh Harvard-Yale-Princeton Club was formally founded on November 7, 1930. The club merged with the Three Rivers Stadium based Allegheny Club in 2002 after Allegheny had filed for bankruptcy protection.

The Centre City Tower (also spelled Center City Tower) is a 341-foot (104 m) tall skyscraper in Pittsburgh, Pennsylvania. It contains 26 floors, and stands as the 20th-tallest building in the city. Centre City Tower was constructed in 1971, and was later renovated in 2002. The entire building contains Class B office space, and is an example of modern architecture. Signage for Huntington Bank, the building's major tenant, adorns the outside of the structure.

The James Reed Building or the Reed Smith Building is a historic building in Pittsburgh. It was constructed in 1902. It is in the Beaux-Arts architecture style. For many years, the primary tenant had been Reed Smith law firm. The buildings namesake is one of Reed Smiths founders, James Hay Reed. Reed Smith bought the nine-story building in 1984 for $5.82 million as 435 Sixth Ave Associates. In 2007 Reed Smith decided to relocate its corporate headquarters to Three PNC Plaza and sell the building, which had a market value of $16.78 million. The downtown Pittsburgh office vacancy rate at the time was 20%, driving down the value of the building. In October 2008, the building was purchased by Mika Realty Group of Los Angeles for $6.5 million. Mika Realty, owned by Michael Kamen and Gerson Fox, purchased the building under the name 600 William Penn Partners LLC. Kamen and Fox also purchased the nearby Union Trust Building 6 months prior.In 2009, Reed Smith law firm moved its corporate headquarters to Three PNC Plaza. Mika Realty was never able to find a tenant to replace Reed Smith, the building remained vacant, which led to bankruptcy in 2011. PMC Property Group purchased the building in September 2012 for $5.5 million in a U.S. Bankruptcy Court auction in Los Angeles.The building was redeveloped into a 249-room Hotel Monaco, opened in January 2015.