Museo de la Música Puertorriqueña

Casa Salazar-Candal (English: Salazar–Candal House) is a historic building located on the southeast corner of Isabel and Mayor Cantera streets in Ponce, Puerto Rico, in the city's historic district. The building dates from 1911. It was designed by the architect Blas Silva. The architecture consists of 19th Classical revival, Art Nouveau and Spanish Revival architectural styles. Today the Salazar–Candal Residence houses the Museum of the History of Ponce.

The Museo de la Historia de Ponce (Museum of the History of Ponce) is a local history museum located in the historic Casa Salazar-Candal in the city of Ponce, Puerto Rico. The museum depicts the city's ecology, economy, architecture, government, and elements of daily life. It seeks to promote the research, conservation, and dissemination of the historic heritage of Ponce and Puerto Rico.Inaugurated on 12 December 1992, it was the first museum in Puerto Rico established to cover the history of the people of a town or city. It traces the city's history from the Taino Indians to today. The museum was inaugurated under the administration of Mayor Rafael Cordero Santiago, as part of the tricentennial celebration of the founding of the city.It is located in the historic district of the city, a short two-block walk from the central Plaza Las Delicias town square, at the southeast corner of Isabel and Mayor Cantera streets. The museum proper is housed in the historic Casa Salazar-Candal but also includes the neighboring Rosali-Zapater house, which houses administratives offices of the museum, in addition to the empty lot that once held the residence of the Schuck Gelpí family. In 2012, plans were announced to expand the museum into the Casa Rosita Serrallés, an adjacent property. In 2014, Casa Rosita Serralles (Calle Salud street #67) joined Museo de la Historia de Ponce and opened as "Museo de la Recordacion Barrio Mameyes" (Barrio Mameyes Memorial Museum) under Ponce mayor María Meléndez. It is also known as "Sala Memorial del Barrio Mameyes" as it operates as a part of the Museo de la Historia de Ponce.

Teatro La Perla is a historic theater in the city of Ponce, Puerto Rico. Inaugurated in 1864, it is the second oldest theater of its kind in Puerto Rico, but "the largest and most historic in the Spanish-speaking Caribbean." The theater was named La Perla in honor of the Virgin of Montserrat (Spanish: La Virgen de Montserrat), known as "The Pearl of the Mediterranean." It is located in barrio Tercero, in the Ponce Historic Zone.

The Ponce High School is public educational institution in Ponce, Puerto Rico, offering grades nine through twelve. The school's main building is a historic structure located on Cristina Street, in the Ponce Historic Zone. From its beginning the school has secured a unique place in Puerto Rico's educational history. Of over 3,000 schools erected in Puerto Rico in the first quarter of the twentieth century, Ponce High was the largest, "at a time enrolling more students than all the other Puerto Rico high schools combined", and for many years enrolling more students than any other high school in Puerto Rico. The cost of the building in 1915 dollars was $150,000 USD ($4.34 million in 2022 dollars). The building was listed on the U.S. National Register of Historic Places on 4 August 1987. The school has the only diamond-level DECA chapter in Puerto Rico. The Ponce High School building is "among the most important public buildings ever built in Puerto Rico." The school is the oldest continuously-operating high school in Puerto Rico.

Tercero (Barrio Tercero) is one of the 31 barrios of the municipality of Ponce, Puerto Rico. Together with Primero, Segundo, Cuarto, Quinto, and Sexto, Tercero is one of the municipality's six core urban barrios. It was organized in 1878.

Residencia Ermelindo Salazar (Ermelindo Salazar Home) is a historic house in Ponce, Puerto Rico. It was built in 1870 as the home of Ermelindo Salazar, a prominent citizen and businessman in the city as well as its mayor in 1880. It is located at 70 Cristina street in the Ponce Historic Zone, in Barrio Tercero, Ponce, Puerto Rico. Today the house serves as the headquarters of the Centro Cultural de Ponce Carmen Solá de Pereira, the cultural center of the city of Ponce, where it is used for educational and cultural activities as well as for art exhibits.

Centro Cultural Carmen Solá de Pereira de Ponce (English: Carmen Solá de Pereira Ponce Cultural Center) is the cultural center of the city of Ponce, and is located at 70 Cristina street in the Ponce Historic Zone, in Barrio Tercero, Ponce, Puerto Rico. The Center is located in a structure designed in 1870, and it is currently used for educational and cultural activities as well as for art exhibits. Centro Cultural de Ponce was founded on 12 November 1963.

Ponce Honra a su Maestra: Lolita Tizol is a marble statue to the memory of Puerto Rican music schoolteacher Lolita Tizol. It is located on Bolevar Miguel Pou, at the fork of Isabel and Lolita Tizol streets, in Ponce, Puerto Rico. The statue has abundant visibility as it is located in an open area of Tricentennial Park.

Quinto (Barrio Quinto) is one of the 31 barrios of the municipality of Ponce, Puerto Rico. Together with Primero, Segundo, Tercero, Cuarto, and Sexto, Quinto is one of the municipality's six original urban barrios. It was organized in 1878.

Fundación Biblioteca Rafael Hernández Colón (English: Rafael Hernández Colón Foundation Library) is a gubernatorial library and museum that records the political life of three-term governor of Puerto Rico, Rafael Hernández Colón. It was founded in 1992 and in September 2015 it moved to its current location at the southeast corner of Calle Mayor and Calle Castillo in Ponce, Puerto Rico, in the Ponce Historic Zone.

Casa Font-Ubides (English: Font-Ubides House), also known as the Residencia Monsanto (English: Monsanto Residence) is a historic building located on the north side of Castillo Street in Ponce, Puerto Rico, in the city's historic district. The building dates from 1913. It was designed by the architect Blas Silva. The architecture consists of 19th Classical revival and Art Nouveau architectural styles. The building is of architectural significance for its aggressive incorporation of curvilinear forms and ornaments. The complete preservation of the original architecture of the Monsanto Residence, its unique design amongst the houses of Ponce, and its location within the historic urban core of the city qualify it as one of a series of grand houses and an integral part of the character of Ponce.

Hotel Meliá is a historic colonial style family owned and operated hotel located in the Ponce Historic Zone in Ponce, Puerto Rico. It is the oldest continuously operating hotel in Puerto Rico. Hotel Meliá, which was founded over 60 years before the much larger Meliá Hotels International chain opened its first lodging facility, bears no relation to the multi-hotel chain headquartered in Spain.