Centro Cultural Carmen Solá de Pereira de Ponce

Residencia Ermelindo Salazar (Ermelindo Salazar Home) is a historic house in Ponce, Puerto Rico. It was built in 1870 as the home of Ermelindo Salazar, a prominent citizen and businessman in the city as well as its mayor in 1880. It is located at 70 Cristina street in the Ponce Historic Zone, in Barrio Tercero, Ponce, Puerto Rico. Today the house serves as the headquarters of the Centro Cultural de Ponce Carmen Solá de Pereira, the cultural center of the city of Ponce, where it is used for educational and cultural activities as well as for art exhibits.

Hotel Meliá is a historic colonial style family owned and operated hotel located in the Ponce Historic Zone in Ponce, Puerto Rico. It is the oldest continuously operating hotel in Puerto Rico. Hotel Meliá, which was founded over 60 years before the much larger Meliá Hotels International chain opened its first lodging facility, bears no relation to the multi-hotel chain headquartered in Spain.

Teatro La Perla is a historic theater in the city of Ponce, Puerto Rico. Inaugurated in 1864, it is the second oldest theater of its kind in Puerto Rico, but "the largest and most historic in the Spanish-speaking Caribbean." The theater was named La Perla in honor of the Virgin of Montserrat (Spanish: La Virgen de Montserrat), known as "The Pearl of the Mediterranean." It is located in barrio Tercero, in the Ponce Historic Zone.

Los Chinos de Ponce (English: "The Chinesemen of Ponce"), formally King's Cream, is an Ice cream parlor located at Calle Marina 9322 in the city of Ponce, Puerto Rico, in front of the town square, Plaza Degetau, opposite the historic Parque de Bombas. Critics have called the site "a Puerto Rican institution" and its ice cream "the Caribbean's best." It has also been called "Puerto Rico's most famous ice cream stand." Another critic called it "[the reason] for which I'll always remember Ponce."

The Banco Crédito y Ahorro Ponceño building (or Banco Crédito, for short), a historic building in Ponce, Puerto Rico, was the first and main office of the historic Banco Crédito y Ahorro Ponceño (English: Ponce Credit and Savings Bank), and represents one of the last examples of the once popular turn-of-the-century eclectic architecture. The building was listed on the U.S. National Register of Historic Places on June 25, 1987. It was built in 1924. The building was owned by Banco Crédito y Ahorro Ponceño which was one of the largest banking companies in the country of Puerto Rico during most of the twentieth century.

Casa Salazar-Candal (English: Salazar–Candal House) is a historic building located on the southeast corner of Isabel and Mayor Cantera streets in Ponce, Puerto Rico, in the city's historic district. The building dates from 1911. It was designed by the architect Blas Silva. The architecture consists of 19th Classical revival, Art Nouveau and Spanish Revival architectural styles. Today the Salazar–Candal Residence houses the Museum of the History of Ponce.

The Museo de la Historia de Ponce (Museum of the History of Ponce) is a local history museum located in the historic Casa Salazar-Candal in the city of Ponce, Puerto Rico. The museum depicts the city's ecology, economy, architecture, government, and elements of daily life. It seeks to promote the research, conservation, and dissemination of the historic heritage of Ponce and Puerto Rico.Inaugurated on 12 December 1992, it was the first museum in Puerto Rico established to cover the history of the people of a town or city. It traces the city's history from the Taino Indians to today. The museum was inaugurated under the administration of Mayor Rafael Cordero Santiago, as part of the tricentennial celebration of the founding of the city.It is located in the historic district of the city, a short two-block walk from the central Plaza Las Delicias town square, at the southeast corner of Isabel and Mayor Cantera streets. The museum proper is housed in the historic Casa Salazar-Candal but also includes the neighboring Rosali-Zapater house, which houses administratives offices of the museum, in addition to the empty lot that once held the residence of the Schuck Gelpí family. In 2012, plans were announced to expand the museum into the Casa Rosita Serrallés, an adjacent property. In 2014, Casa Rosita Serralles (Calle Salud street #67) joined Museo de la Historia de Ponce and opened as "Museo de la Recordacion Barrio Mameyes" (Barrio Mameyes Memorial Museum) under Ponce mayor María Meléndez. It is also known as "Sala Memorial del Barrio Mameyes" as it operates as a part of the Museo de la Historia de Ponce.

The Banco de Ponce building, a historic building in Ponce, Puerto Rico, was the first and main office of Banco de Ponce until the company merged with Banco Popular in 1990. Though its headquarters had moved to a presumptuous building in Hato Rey's Milla de Oro by then, Banco de Ponce continued to consider this building its main office, until the company merged with Banco Popular in 1990. The building was listed on the U.S. National Register of Historic Places on June 25, 1987. It was built in 1924.

Banco de Ponce was the Puerto Rican bank with the largest number of branches in the United States and second largest bank in deposits and number of branches in Puerto Rico during the twentieth century. Founded in Ponce, Puerto Rico, in the early part of the century, it headquartered in San Juan in 1970 and, 20 years later, merged with Banco Popular forming BancPonce Corporation.

Banco Crédito y Ahorro Ponceño (Ponce Credit and Savings Bank) was the first bank in Ponce, Puerto Rico, and one of the first two native Puerto Rican banks to be established in Puerto Rico. The bank was the first one to introduce a bank credit card to the Puerto Rican market. With over 50 branches throughout the island, the bank was one of the largest banking companies in Puerto Rico during most of the twentieth century. Founded in 1895, Banco Crédito built its own first banking structure in 1924 at Calle Marina and Callejón Amor, in Ponce. This first branch office, located in what is today the Ponce Historic Zone, has since been declared historic and was listed in the National Register of Historic Places.The bank collapsed in 1978 and was acquired by the Federal Deposit Insurance Corporation. Its accounts and assets were purchased by Banco Popular de Puerto Rico and Banco Santander.

The Parque de Bombas (English: firehouse) is a historic former fire station in Ponce, Puerto Rico. It is one of Puerto Rico's most notable buildings, with some considering it "by far the most easily recognized landmark in the Island." It is located at the Plaza Las Delicias town square, directly behind Ponce Cathedral. Originally built in 1882 as a pavilion for an exhibition, it became Puerto Rico's first ever fire station. In 1990, the fire station closed and was converted into a museum. It was listed in the National Register of Historic Places on 12 July 1984.

Museo Parque de Bombas (Parque de Bombas Museum) is a museum located inside the historic Parque de Bombas in the Ponce Historic Zone in Ponce, Puerto Rico. This museum is located at the Plaza Las Delicias town square, directly behind the Ponce Cathedral. It is housed in a building that once housed the city's main (and, initially, its only) firehouse. The building where the museum is located, has been heralded both for its historical and architectural roles in Puerto Rican society. Historically, it was Puerto Rico's first ever fire station. The building is listed in the National Register of Historic Places.As municipal firehouses in Puerto Rico were reorganized into a commonwealth-level agency in 1943, called the Firemen Services of Puerto Rico, a more modern spacious firehouse was built in the 1960s a block from Parque de Bombas. The new modern firehouse, now itself occupied by Instituto de Música Juan Morel Campos, displaced the now-historic Parque de Bombas into more of a supportive and administrative firefighting role, whereas the new firehouse, located at Calle Cristina and Calle Mayor streets, became the main firehouse for the town. In 1990, after 108 years of uninterrupted service as a firehouse, the Parque de Bombas firehouse was turned into the Museo Parque de Bombas. The museum traces the people and events of the Ponce firefighters throughout its history. The museum opened under the administration of Mayor Rafael Cordero Santiago. The architect who rebuilt and reconditioned the structure into a museum in 1990 was Pablo Ojeda O'Neill. At over 100,000 visitors per year, it is Ponce's most visited museum, and Puerto Rico's second most visited landmark, after Castillo El Morro.