Cathedral of Saint Paul (Worcester, Massachusetts)

The Enterprise Building is an historic commercial building at 540 Main Street in Worcester, Massachusetts. When it was built in 1900, this five story brick building achieved notice for its elaborate Beaux Arts decorations. The building was listed on the National Register of Historic Places in 1980.

The Saint Joseph's Home for Working Girls is an historic social services building at 52 High Street in downtown Worcester, Massachusetts. Completed in 1924, it was operated for many years as a home for needy women by the Sisters of Mercy. Since 2009 it has been home to Abby's House, which continues the same mission. The building, designed by Edward Fitzgerald, was listed on the National Register of Historic Places in 2021.

The Harold D. Donohue Federal Building and United States Courthouse, formerly known as the U.S. Post Office and Courthouse, is a courthouse of the United States District Court for the District of Massachusetts located in Worcester, Massachusetts.

Colton's Block is an historic series of commercial buildings at 586-590 Main Street in Worcester, Massachusetts. Built in the 1860s, it consists of three separate yet similarly-styled buildings separated by firewalls. It is the only surviving example of a commercial building style that was common in Worcester at the time. The building was listed on the National Register of Historic Places in 1980. It is now mostly occupied by residences.

The Park Building is an historic building in Worcester, Massachusetts, USA. Built in 1914, the 11 story structure was for many years one of Worcester's most prominent landmarks. It has a steel frame, with an exterior that is dressed predominantly in limestone. The first two floors have metal and plate glass store fronts, while the third floor has evenly spaced windows, separated by decorative limestone panels and topped by a cornice. From the fourth to the ninth floors there is little decoration. The top two floors have groups of windows separated by Tuscan columns, giving the appearance of a loggia.The building was listed on the National Register of Historic Places in 1980. As of 2016 it is an apartment building known as Park Plaza that is part of the Grid District, a commercial urban redevelopment project in downtown Worcester.

The Hanover Theatre and Conservatory for the Performing Arts in Worcester, Massachusetts, United States was originally built in 1904 as the Franklin Square Theatre regularly scheduling burlesque shows, Broadway touring shows and headline acts transitioning to showing silent films by 1912 when vaudeville magnate Sylvester Poli purchased the theatre from the estate of Pauline L. Taylor.

The Grid District is a collection of buildings in downtown Worcester, Massachusetts.

Stevens' Building is a historic commercial building located at 24–44 Southbridge Street in downtown Worcester, Massachusetts. It is one of the city's most imposing mid-19th century buildings. The brick building is four stories for most of its length on Southbridge Street, and also presents a finished facade to Burnside Court. The central portion rises to a full five stories with a flat roof, while the north and south sections are four floors with a low pitch roof. The oldest portion of the building was the central portion, built sometime in the 1850s. The Stevens Brothers, manufacturers of wooden architectural building parts, purchased this building c. 1867, extended it northward to Burnside Court, and used it as factory space. By 1870 they had bought the land south of the building, and erected as a freestanding building seven bays of the present building. The two buildings were then joined together later in the 1870s. The fifth floor of the central section was probably added after a fire in the early 1900s.The building was listed on the National Register of Historic Places in 1980.

The Babcock Block is a historic commercial building at 596 Main Street in Worcester, Massachusetts. Built in the 1860s, it is a rare example of granite construction in the period. It was listed on the National Register of Historic Places in 1980.

Worcester Plaza (formerly known as Worcester County National Bank Tower) is a building located in downtown Worcester, Massachusetts at 446 Main Street. Designed by Kevin Roche John Dinkeloo and Associates, it was completed in 1974, and is currently tied with The 6Hundred as the tallest building in Worcester. It stands 289 feet (88 m) tall, is 24 stories high, and has 244,000 square feet (22,700 m2) of total floor space. Its façade is completely glass, similar to the 790-foot (240 m) John Hancock Tower in nearby Boston. The current building was built instead of a larger, more iconic design announced in 1969 that was never realized. The original design was a 696 feet (212 m) tall, 50 story, slender tower with an angled crown and would have been the "highest standing commercial building in New England.The building was most recently sold in October 2019 to Boston-based Synergy Investments for $16.5 million. It previously sold for $21.5 million in 2000.

The Lower Pleasant Street District is an historic district at 418–426 Main Street and 9–49 Pleasant Street in Worcester, Massachusetts. It encompasses the only surviving row of Victorian-era commercial buildings in downtown Worcester. These buildings were built between 1872 and 1890, and are located along the north side of Pleasant Street, from its corner with Main Street nearly to Chestnut Street. 39 Pleasant Street is the location of Str8Up Entertainment. The most unusual of the six buildings is the Odd Fellows Hall at 9-15 Pleasant Street, which is the only commercial Gothic Revival building left in the city.The district was listed on the National Register of Historic Places in 1980.

The Horatio Tower House is a historic house at 71 Pleasant Street in Worcester, Massachusetts. It is one of the few relatively intact surviving instances of Italianate styling on the west side of the city. This two story frame house was built for Horatio Tower, a local builder whose work included the American Antiquarian Society hall and Mechanics Hall. Although the building has some Greek Revival features (such as the corner pilasters), its significant Italianate features include the deep cornice with brackets, and a front entry porch supported by Corinthian columns and a similarly styled roof.The house was listed on the National Register of Historic Places in 1980.