Upcountry History Museum

The Greenville County Museum of Art (GCMA) is an art museum located in Greenville, South Carolina. Its collections focus mainly on American art, and its holdings include works by Andrew Wyeth, Josef Albers, Jasper Johns (raised in South Carolina), Andy Warhol, Romare Bearden, Jacob Lawrence, Ronnie Landfield, Helen Turner, Mary Tannahill, Eric Fischl, Marylyn Dintenfass, and Leon Golub. Southern American and South Carolina-based artists, such as Henrietta Johnston, are also represented.

Hampton Pinckney is a neighborhood and national historic district located in Greenville, South Carolina. One of the oldest neighborhoods in Greenville, it was where the textile industry was started in the early 19th century and lasted until the 1920s. The first trolley car in Greenville was installed in this neighborhood in 1899, opening for business in 1901. It encompasses 70 contributing buildings in a residential section of Greenville. The houses date from about 1890 to 1930, and include Italianate, Greek Revival, Queen Anne, various bungalows, and examples of Gothic Revival and Colonial Revival design, as well as vernacular forms. The oldest house in the district is the McBee House (ca. 1835).It was added to the National Register of Historic Places in 1977, with a boundary increase in 1982.

Heritage is a neighborhood located in Greenville, South Carolina. Located northwest of the city, it is home to the St. George Greek Orthodox Church and was once home to a dairy. The neighborhood was subdivided in 1909 and experienced peak construction during the 1920s.

Third Presbyterian Church is a historic church in Greenville, South Carolina, restored as a place of worship by the congregation of Trinity Church of Greenville, for which the latter received a 2016 State Preservation Honor Award from the South Carolina Department of Archives and History and the Palmetto Trust for Historic Preservation.

The 1946 Greenville propane explosion occurred on 19 November 1946, at the Ideal Laundry laundromat in Greenville, South Carolina. A tank containing around 3,500 US gallons (13 m3) of propane exploded around 6 PM, after leaking vapors were ignited by the boilers in the basement. The blast, which killed 6 people and injured over 150, was felt as far away as Gaffney, 50 miles to the northeast.

Downtown Baptist Church, is a historic church building located at 101 W. McBee Avenue in Greenville, South Carolina. It was constructed in 1858 as the new home of First Baptist Church of Greenville, replacing an earlier structure on the banks of the Reedy River. The congregation of First Baptist Church vacated the site for a new campus on Cleveland Street in the late 1970s at which time a minority of the congregation elected to remain at the downtown site and start a new church under the name Downtown Baptist Church. The Greek Revival building, designed by architect Samuel Sloan, was built in 1858 and added to the National Register of Historic Places in 1977. In 2011, the building was renovated, removing side galleries and balconies that were added in 1915. It is now the home of Grace Church.

The Old Beth Israel Synagogue is a former Orthodox Jewish synagogue located at 307 Townes Street in the Stone Avenue neighborhood of Greenville, South Carolina, in the United States. The historical former synagogue building, after being repurposed as a church and later commercial building, is now used as a private residence.

Imperial Hotel, also known as Hotel Greenville, is a historic hotel building located at Greenville, South Carolina. It was built in 1911–1912, and is a seven-story, U-shaped skyscraper with a buff-colored brick veneer over a steel frame. It was originally a 90-room hotel, and expanded by 1930 to 250 rooms. The hotel closed in the early 1970s, but this establishment is still used as a nursing home for disabled people 55 and over. An adjacent parking garage was demolished in the 1980s. It was added to the National Register of Historic Places in 1982.New owners of the building plan extensive building renovations in 2019.

Col. Elias Earle Historic District is a national historic district located at Greenville, South Carolina. It encompasses 74 contributing buildings in a middle-class neighborhood of Greenville. The houses primarily date from about 1915 to 1930, and include Neoclassical, Colonial Revival, Tudor Revival, and bungalow styles. The district was originally part of the estate of Colonel Elias Earle, a prominent early-19th century Greenville citizen. The Earle St. Baptist Church is located in the district.It was added to the National Register of Historic Places in 1982.

The Landmark Building, also known as the Daniel Building, is an office skyscraper in Downtown Greenville, South Carolina. At 305 ft (93 m), it was the tallest building in South Carolina from 1966 to 1983. With 25 stories, the skyscraper has been the tallest structure in Greenville since its completion in 1966. It was conceived by Charles E. Daniel, a United States senator who was known for his love of construction.

Whitehall is a historic home located at Greenville, South Carolina. It was built in 1813 as a summer residence by Charlestonian Henry Middleton on land purchased from Elias Earle. Whitehall served as Middleton's summer home until 1820. It is a simple white frame structure with shuttered windows and wide first and second story galleries, or piazzas, in the Barbadian style.It was added to the National Register of Historic Places in 1969.

The Confederate Monument (Greenville, South Carolina) is a shaft of granite topped by a marble statue of a soldier—the oldest public sculpture in Greenville—that memorializes the Confederate dead of the American Civil War from Greenville County, South Carolina. The monument is flanked by two period Parrott rifles manufactured at the West Point Foundry.