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Kendall Square is a neighborhood in Cambridge, Massachusetts, US, with the square itself at the intersection of Main Street and Broadway. It also refers to the broad business district east of Portland Street, northwest of the Charles River, north of MIT and south of Binney Street. Kendall Square has been called "the most innovative square mile on the planet", in reference to the high concentration of entrepreneurial start-ups and quality of innovation which have emerged in the vicinity of the square since 2010.The neighborhood has about 50,000 people who work in the area on a daily basis and a growing residential population.

Galaxy: Earth Sphere is a 1989 fountain and sculpture by Joe Davis, installed in Kendall Square, Cambridge, Massachusetts, United States. The artwork was designed to emit streams of low-temperature steam from time to time, but the pipes sourcing this emission have been broken for some time.

The MIT Sloan School of Management (MIT Sloan or Sloan) is the business school of the Massachusetts Institute of Technology, a private university in Cambridge, Massachusetts. MIT Sloan offers bachelor's, master's, and doctoral degree programs, as well as executive education. Its degree programs are among the most selective in the world. MIT Sloan emphasizes innovation in practice and research. Many influential ideas in management and finance originated at the school, including the Black–Scholes model, the Solow–Swan model, the random walk hypothesis, the binomial options pricing model, and the field of system dynamics. The faculty has included numerous Nobel laureates in economics and John Bates Clark Medal winners.

The MIT Press is a university press affiliated with the Massachusetts Institute of Technology (MIT) in Cambridge, Massachusetts (United States). It was established in 1962.

The Arthur D. Little Inc., Building is a National Historic Landmark at 30 Memorial Drive in Cambridge, Massachusetts. The building was constructed in 1917 for the Arthur D. Little Company alongside the campus of the Massachusetts Institute of Technology and now serves as headquarters for the dean of the MIT Sloan School of Management and other Sloan administrative groups.The Arthur D. Little Company was founded in 1886 by Arthur Dehon Little, and was originally located on Milk Street in Boston. The three story brick building on Memorial Drive was constructed by the company to meet increasing demand for laboratory space, and is an architecturally unexceptional commercial structure. The building was declared a National Historic Landmark for its association with the Little company, the first business to be established as a consulting laboratory in the nation. Prior to its founding, individual businesses established their own research laboratories to make technological innovations. Little, and his partner William H. Walker, were among the first academically oriented researchers to create a consulting laboratory whose services could be hired by businesses. At first focused on the chemistry of cellulose and its uses in textiles and paper, the company was by 1909 the largest consulting industrial laboratory in the nation, and worked a wide array of research disciplines. Little was an early advocate of the importance of technological innovation, recognizing its importance in maintaining commercial success. He ran the company until his death in 1935, and willed his shares to MIT. The building was added to the National Register of Historic Places in 1976.

Kendall/MIT station is an underground rapid transit station in Cambridge, Massachusetts. It serves the MBTA Red Line, Located at the intersection of Main Street and Broadway, it is named for the primary areas it serves - the Kendall Square business district and the Massachusetts Institute of Technology (MIT). Opened in March 1912 as part of the original Cambridge subway, Kendall/MIT has two side platforms serving the line's two tracks. The Kendall Band, a public art installation of hand-operated musical sculptures, is located between the tracks in the station with controls located on the platforms. Kendall/MIT station is accessible. With 17,018 weekday boardings by a FY2019 count, Kendall/MIT has the fourth highest ridership among MBTA subway stations.

The Kendall Band is a three-part musical sculpture created between 1986 and 1988 by Paul Matisse, who is the grandson of French artist Henri Matisse and stepson of surrealist artist Marcel Duchamp. It is installed between the inbound and outbound tracks of the Massachusetts Bay Transportation Authority's Kendall Station located in Cambridge, Massachusetts near the MIT campus. As of 2007, the art work was seen by an estimated 12,518 riders on an average weekday, and originally cost $90,000 to construct.The three parts of the interactive work are called Pythagoras, Kepler, and Galileo, and are all controlled by levers located on the subway platforms.

The John A. Volpe National Transportation Systems Center or simply Volpe in Cambridge, Massachusetts, is a center of transportation and logistics expertise, operating under the United States Department of Transportation (U.S. DOT). The Volpe Center is named after Governor of Massachusetts and U.S. Secretary of Transportation John Volpe, and its work includes a broad mix of projects that cut across traditional transportation modes and technical disciplines including the Federal Aviation Administration's Enhanced Traffic Management System (ETMS) and Safety Performance Analysis System (SPAS), and the Federal Motor Carrier Safety Administration's SafeStat Online. The Center assists federal, state, and local governments, industry, and academia in a number of areas of consultation including human factors research, system design, implementation and assessment, global tracking, strategic investment and resource allocation, environmental preservation, and organizational effectiveness. Volpe is part of the U.S. DOT's Research and Innovative Technology Administration. However, it differs from most federal organizations in that it receives no direct appropriation from Congress. Instead, it is funded 100% through a fee-for-service structure in which all costs are covered by sponsored project work (approx. $200 million annually).

The Electronics Research Center (ERC) was a NASA research facility located in Cambridge, Massachusetts, across the street from MIT at Kendall Square. The ERC opened in September 1964, taking over the administration of contracts, grants, and other NASA business in New England from the antecedent North Eastern Operations Office (created in July 1962), and closed in June 1970. The campus is now the site of the United States Department of Transportation's John A. Volpe National Transportation Systems Center.

Cambridge Center is a development complex located in the Kendall Square section of Cambridge, Massachusetts, along Broadway and Main streets. The project was started in 1979 and continues in progress to this day.Currently, Cambridge Center is host to the Cambridge Marriott, a Legal Sea Foods restaurant, and many small to medium-sized companies. It is located in Kendall Square, near the Kendall/MIT MBTA red line stop. Some of the buildings have MIT designations and are partially used for academic and research purposes.Alphabet Inc has its Cambridge office split across three buildings in Cambridge Center.On September 16, 2011, an initiative by the City of Cambridge was unveiled called the Entrepreneur Walk of Fame. The walk of fame seeks to highlight individuals that have made contributions to innovation in the global business community.

The Institute for Medical Engineering and Science or IMES is a research institute at the Massachusetts Institute of Technology that aims to combine engineering, medicine, and science to solve challenges in human health. The institute was established in 2012 and is currently directed by Elazer Edelman. Some core faculty members include Alex K. Shalek, Emery Brown, and Ellen Roche. IMES serves to bring together scientific advances with clinical medicine by serving as the point of intersection with major hospitals and industry partners. IMES is also the MIT home for the Harvard–MIT Program in Health Sciences and Technology.

The Kendall Hotel, or The Kendall Hotel, is a boutique hotel on Main St. in the Kendall Square area of Cambridge, Massachusetts. It repurposed a firehouse built in 1895: it was once the Engine 7 Firehouse. The Telegraph's online review terms it a "gorgeous Victorian firehouse turned boutique hotel near buzzy Kendall Square" and asserts that its "Black Sheep restaurant is a gem."It was originally designed to support horse-drawn fire-fighting equipment. It served in fire protection from 1895 to 1993, its role replaced by a modern fire station in Central Square. The building was renovated starting in 2000. Renovation involved moving the original three-story firehouse closer to the street, adding a seven-story tower behind, and restoring two cupolas. After opening in 2002, it was expanded in 2007 with the addition of a second seven-story tower.The hotel is a member of the Historic Hotels of America.The owners have been honored by the Cambridge Historical Commission for the quality of their historic preservation efforts.The Washington Post in 2017 included "Kendall Hotel at the Engine 7 Firehouse" in a list of 23 American "hotel retrofits", as "part of a trend toward historic adaptive reuse that has travelers overnighting in former department stores, textile mills, an auto assembly plant and even a 19th-century jail.".In 2018, Boeing was to become a tenant next door.