Toronto General Hospital

The McEwen Centre for Regenerative Medicine was established at University Health Network in Toronto in 2003, with a donation from Rob and Cheryl McEwen, which they matched in 2006 with a second donation. The McEwen Centre's vision is to be a world-renowned centre for stem cell biology and regenerative medicine. To achieve this ambitious goal, the team of McEwen Investigators is working together to accelerate the development of more effective treatments for conditions such as heart disease, diabetes mellitus, respiratory disease and spinal cord injury. The McEwen Centre is based in the heart of Toronto's Discovery District at the MaRS Centre/Toronto Medical Discovery Tower. The current Director of the McEwen Center for Regenerative Medicine is Prof. Gordon Keller, Canada Research Chair in Embryonic Stem Cell Biology.

MaRS Discovery District is a not-for-profit corporation founded in Toronto, Ontario, Canada in 2000. Its stated goal is to commercialize publicly funded medical research and other technologies with the help of local private enterprises and as such is a public-private partnership. As part of its mission MaRS says, "MaRS helps create successful global businesses from Canada's science, technology and social innovation." As of 2014, startup companies emerging from MaRS had created more than 4,000 jobs, and in the period of 2011 to 2014 had raised over $750 million in capital investments.The name MaRS was originally drawn from a file name, and later attributed with the title "Medical and Related Sciences." It has since abandoned this association as it also works in other fields such as information and communications technology, engineering, and social innovation.

The Ontario Institute for Cancer Research (OICR) is a not-for-profit organization based in Toronto, Ontario, Canada that focuses on the prevention, early detection, diagnosis and treatment of cancer. OICR intends to make Ontario more effective in knowledge transfer and commercialization while maximizing the health and economic benefits of research findings for the people of Ontario. OICR was launched in 2005 by the Government of Ontario, which provides funding through the Ministry of Colleges and Universities. The Institute employs more than 300 people at its research hub at the MaRS Centre in downtown Toronto and funds more than 1,900 scientific staff at hospital-based research institutes and universities around the province. In 2018 it was the highest funder of cancer research in Canada.

The Discovery District is one of the commercial districts in Downtown Toronto, Ontario, Canada. It has a high concentration of hospitals and research institutions, particularly those related to biotechnology. The district is roughly bounded by Bloor Street on the north, Bay Street on the east, Dundas Street on the south, and Spadina Avenue on the west.

The Donald K. Johnson Eye Centre is Canada's largest clinical and research institute for vision. It is located in Toronto at the Toronto Western Hospital.

The Hospital for Sick Children (HSC), corporately branded as SickKids, is a major pediatric teaching hospital located on University Avenue in Toronto, Ontario, Canada. Affiliated with the Faculty of Medicine of the University of Toronto, the hospital was ranked the top pediatric hospital in the world by Newsweek in 2021.The hospital's Peter Gilgan Centre for Research and Learning is believed to be the largest pediatric research tower in the world, at 69,677.28 square metres (750,000.0 sq ft).

The Lunenfeld-Tanenbaum Research Institute is a medical research institute in Toronto, Ontario and part of the Sinai Health System. It was originally established in 1985 as the Samuel Lunenfeld Research Institute, the research arm of Mount Sinai Hospital, by an endowment from the Lunenfeld and Kunin families. It was renamed to the current name on June 24, 2013, after a $35 million donation from Larry and Judy Tanenbaum. It comprises 36 principal investigators, has a budget of C$90 million (2005/6), has over 200 trainees and approximately 600 staff. The institute conducts research into various forms of cancer (colon, breast, pancreatic, prostate, lung, etc.), neurological disorders and brain illnesses, women's and infants' health, diabetes, developmental biology, stem cell biology and tissue regeneration, mouse models of human disease, genomic medicine and systems biology. The institute has 100,000 sq ft (9,300 m2) of space and is split between the main hospital and the Joseph and Wolf Lebovic Health Complex. The Lunenfeld-Tanenbaum Research Institute is a world pioneer in the fields of Systems Biology, Diabetes, and Infectious Bowel Disease. Its Systems Biology team consistently ranked Top 5 worldwide. Researchers at the Lunenfeld have the highest per capita funding and citations in Canada. The founding director was Louis Siminovitch (1984–1994), followed by Alan Bernstein (1995–2000), Janet Rossant and Anthony Pawson (2001–2002), Anthony Pawson (2002–2005) and James Woodgett (2005–).

The Ontario Firefighters Memorial is a monument in Toronto's Queen's Park, in Ontario, Canada.

Victoria Hospital for Sick Children is a building in Toronto, Ontario, Canada. The building served as a hospital until 1951 and currently serves as a blood centre. The building has received a Commendation of Adaptive Re-use from the Toronto Historical Board.

The Frost Building is a curved 7 and 6 storey office building complex on the south east side of Queen's Park Crescent in Toronto, Ontario, Canada. The building is owned by the Government of Ontario and is part of the large Queen's Park campus. The Frost Building is home to various ministries of the Ontario government, primarily the Ministries of Finance and Treasury Board Secretariat. It is divided into a north block (6 storey building was home, in 2014, to parts of the Ministry of Finance and Ministry of Infrastructure) and a south block (7 storey), with the north block located on 95 Grosvenor Street and the south block located on 7 Queen's Park Crescent. A five-storey glass walkway connects the two blocks from the 2nd and 6th floors. The building is named after Leslie Frost, Premier of Ontario for more than a decade starting in 1949. The Frost Building is also commonly referred to as the Ontario Treasury Building. The south block of the building has seven floors; the top floor housing the Office of the Minister of Finance and the Office of the Deputy Minister of Finance. The current Finance Minister of Ontario is Peter Bethlenfalvy and the Deputy Minister of Finance is Greg Orencsak. The building is a landmark of modern office building architecture in Canada, dating from the early 1950s. It was one of the first totally "modern look" buildings without any of the fancy curlicues of older buildings. It was also original in that it follows the curve of the street on which it resides. It is named for former Premier of Ontario Leslie Frost. The north block was built in the 1960s as an addition to the South Block. The Ontario Firefighters' Memorial is located in a small parkette to the southwest corner of the building. Other government buildings nearby include: Ontario Government Buildings - Hearst, Mowat and Hepburn Blocks Whitney Block Ontario Power Building - shares the curve building design with the Frost BuildingThe building is served by the Queen's Park (TTC) subway station to the southwest corner.

Queen's Park is a subway station on Line 1 Yonge–University in Toronto, Ontario, Canada. The station, which opened in 1963, is located under University Avenue at College Street. The station is wheelchair-accessible and has had underground connections to adjoining buildings since 2002. Wi-Fi service is available at this station.

The Princess Margaret Cancer Centre (previously, Princess Margaret Hospital) is a scientific research centre and a teaching hospital in Toronto, Ontario, Canada, affiliated with the University of Toronto Faculty of Medicine as part of the University Health Network. The hospital now stands as the largest cancer centre in Canada and one of the five largest cancer centres in the world. Along with the Odette Cancer Centre, which is also associated with University of Toronto Faculty of Medicine and is independently the sixth largest cancer centre in North America, it forms one of the largest cluster of cancer hospitals in the world.The hospital is situated near the intersection of University Avenue and College Street within the Discovery District of downtown Toronto, an area with high concentration of biomedical research institutions. Named for Princess Margaret, Countess of Snowdon, the hospital is under the royal patronage of Anne, Princess Royal. The hospital specializes in the treatment of cancer, and offers the majority of its services to residents of the Greater Toronto Area. The hospital offers expertise in the fields of surgical oncology, medical oncology, hematology including bone marrow transplantation, radiation oncology, psychosocial oncology, medical imaging, and radiation therapy. The hospital houses 17 radiation treatment machines, all of which are equipped with the latest technologies including IMRT and VMAT, a superficial orthovoltage machine, and operates a Gamma Knife (Perfexion) stereotactic radiosurgery machine in collaboration with Toronto Western Hospital.