Kaplan Medical Center

Route 411 (Hebrew: כביש 411), is the designation of a regional route in the Shephelah region in Israel running southeasterly consolidating previous local roads and new construction. The western section begins at Highway 42 near Kfar Gevirol in western Rehovot and continues just past Route 410. The central section, completed in June 2014, continues to the entrance of Kvutzat Shiller. The eastern section begins just short of Highway 40 south of Rehovot and terminates at Highway 3 towards Jerusalem, bypassing the towns of Kiryat Ekron and Mazkeret Batya.

Kfar Bilu (Hebrew: כְּפַר בִּיל"וּ, lit. Bilu Village) is a moshav in central Israel. Located between Rehovot and Kiryat Ekron, it falls under the jurisdiction of Gezer Regional Council. In 2019 it had a population of 1,258.

Kiryat Ekron or Qiryath Eqron (Hebrew: קִרְיַת עֶקְרוֹן) is a town located on the coastal plain in the Central District of Israel. Located immediately south of the city of Rehovot on Highway 411 next to the Bilu Junction, in 2019 it had a population of 11,001.

Aqir, also spelt Akir and Akkur, was a Palestinian Arab village in the Ramle Subdistrict, located 9 km southwest of Ramla and 1 km north of Wadi al-Nasufiyya (today called Nahal Ekron). It was depopulated and demolished and replaced by Kiryat Ekron.

Brenner Regional Council (Hebrew: מועצה אזורית ברנר, Mo'atza Azorit Brenner; Arabic: المجلس الإقليمي برنر), is a regional council in the Central District of Israel. It is located in the coastal plain, in the vicinity of Rehovot and Yavne. The council is named after writer Yosef Haim Brenner, killed in the Jaffa riots of 1921. The Council was established in 1950, with a jurisdiction of 36,000 dunams. As of 2007, the six communities in the council (two kibbutzim and four moshavim) are home to approximately 6,000 inhabitants.

Kvutzat Shiller (Hebrew: קבוצת שילר), also known as Gan Shlomo (Hebrew: גַּן שְׁלֹמֹה, lit. Solomon's Garden) is a kibbutz in central Israel. Located in the Shephelah near Rehovot, it falls under the jurisdiction of Brenner Regional Council. In 2019 it had a population of 578.

Givat Brenner (Hebrew: גִּבְעַת בְּרֶנֶר, lit. Brenner Hill; Arabic: غفعات برينر), is a kibbutz in the Central District of Israel. Located around two kilometres south of Rehovot, it falls under the jurisdiction of Brenner Regional Council. Founded in 1928, it is named after writer Yosef Haim Brenner, who was killed in the Jaffa riots of 1921. In 2019 it had a population of 2,678. It is the largest kibbutz in Israel.

Gibton (Hebrew: גִּבְּתוֹן, lit. Finch) is a moshav in central Israel. Located near Rehovot, it falls under the jurisdiction of Brenner Regional Council. In 2019 it had a population of 369.

Rehovot (Hebrew: רְחוֹבוֹת Rəḥōvōt, Arabic: رحوڤوت Reḥūfūt) is a city in the Central District of Israel, about 20 kilometers (12 miles) south of Tel Aviv. In 2019 it had a population of 143,904.

De Shalit High School Complex is a high school located in Rehovot, Israel. The school was named after physicist Amos de-Shalit (1926–1969). De Shalit has an enrollment of 2,000 students, from Rehovot and Kiryat Ekron. The school is affiliated with the Weizmann Institute of Science and many of its students participate in science-related projects organized by the Davidson Institute of Science Education.

Zarnuqa (Arabic: زرنوقة), also Zarnuga, was a Palestinian Arab village in the Ramle Subdistrict. It was depopulated on 27–28 May 1948 during the 1948 Arab–Israeli War.

Ganei Yohanan (Hebrew: גַּנֵּי יוֹחָנָן) is a moshav in central Israel. Located in the Shephelah near Rehovot, it falls under the jurisdiction of Gezer Regional Council. In 2019 it had a population of 621.