Orlando Health/Amtrak station

Winnie Palmer Hospital for Women & Babies (WPHfWB) is a nationally ranked, 285-bed non-profit, women and babies hospital located in Orlando, Florida. WPHfWB is a part of the Orlando Health system. As the hospital is a teaching hospital, it is affiliated with the Florida State University College of Medicine's Orlando campus. Additionally, Winnie Palmer Hospital for Women & Babies has a two-story skybridge to connect the hospital to the nearby Arnold Palmer Hospital for Children, which it keeps close affiliations to. The hospital contains one of two pediatric training programs in Orlando Health for medical students.The hospital contains all of Orlando Health's gynecological facilities as well as the maternity department, and all neonatal/neonatal intensive care unit services.

Orlando Regional Medical Center (ORMC) is an 808-bed tertiary hospital in downtown Orlando, Florida designed by HKS, Inc. (architect) and Walter P Moore (structural engineer). It is the flagship of the Orlando Health system.

Orlando Health Arnold Palmer Hospital for Children is a 158-bed pediatric hospital in Orlando, Florida, United States. Arnold Palmer Hospital is part of Orlando Health, and is supported by the Arnold Palmer Medical Center Foundation. Together, the Arnold Palmer Hospital for Children and the Winnie Palmer Hospital for Women & Babies form the Arnold Palmer Medical Center. Arnold Palmer Hospital for Children is also home to the Howard Phillips Center for Children & Families. The Bert Martin's Champions for Children Emergency Department & Trauma Center at Arnold Palmer Hospital is part of the only Level One Trauma Center in the areaAs of the 2016-2017 rankings, Arnold Palmer Hospital is nationally ranked as a “Best Children’s Hospital” by U.S. News & World Report in five pediatric specialties - cardiology & heart surgery, diabetes & endocrinology, gastroenterology & GI surgery, orthopedics and urology.Arnold Palmer Hospital for Children has affiliations with Camp Boggy Creek, Children's Miracle Network, the Florida Association of Children's Hospitals, Give Kids the World, the Make-A-Wish Foundation, the National Association of Children's Hospitals and Related Institutions, and the Ronald McDonald House.

Orlando Health is a private, not-for-profit network of community and specialty hospitals based in Orlando, Florida. Orlando Health is Central Florida’s fourth largest employer with nearly 29,000 employees and more than 4,500 affiliated physicians.

On June 12, 2016, Omar Mateen, a 29-year-old man, killed 49 people and wounded 53 more in a mass shooting at Pulse, a gay nightclub in Orlando, Florida, United States. Orlando Police officers shot and killed him after a three-hour standoff. In a 9-1-1 call made shortly after the shooting began, Mateen swore allegiance to the leader of the Islamic State of Iraq and Syria, Abu Bakr al-Baghdadi, and said the U.S. killing of Abu Waheeb in Iraq the previous month "triggered" the shooting. He later told a negotiator he was "out here right now" because of the American-led interventions in Iraq and in Syria and that the negotiator should tell the United States to stop the bombing. The incident was deemed a terrorist attack by FBI investigators. Pulse was hosting a "Latin Night", and most of the victims were Latino. It is the deadliest incident in the history of violence against LGBT people in the United States, and was the deadliest mass shooting by a single gunman in U.S. history until the 2017 Las Vegas shooting.

The J. J. Bridges House is a historic house located at 704 South Kuhl Avenue in Orlando, Florida. It is locally significant as the first of the highly academic Colonial Revival style homes built in the city.

The Griffin Park Historic District is a U.S. historic district (designated as such on July 18, 1996) located in Orlando, Florida. The district is bounded by Avondale and South Division Avenues, Carter Street, and I-4. It contains 26 historic buildings.

Downtown Orlando is the historic core and central business district of Orlando, Florida, United States. It is bordered by Marks Street in the north, Mills Avenue (SR 15) in the east, Orange Blossom Trail (US 441) in the west, and Kaley Avenue in the south. There are several distinct neighborhoods in downtown; "North Quarter" to the north, "Lake Eola Heights Historic District" just north of Lake Eola, "South Eola" contains Lake Eola Park and continues to the east and south of Lake Eola, "Thornton Park" in the east, "Parramore" in the west, "Lake Cherokee Historic District" to the south, and the "Central Business District" (or the "Financial District") between Colonial Drive and Lake Lucerne in the center. In 2010, the estimated population of downtown was 18,731. The daytime population was estimated to be 65,000 (in 2010). The 5-mile radius population of downtown is 273,335.

The Dr. P. Phillips House (also known as the Peleg Peckham House) is a historic home in Orlando, Florida. It is located at 135 Lucerne Circle, Northeast. On July 10, 1979, it was added to the U.S. National Register of Historic Places.

CNL Center City Commons is a complex of buildings in Downtown Orlando. The main building is a 250 foot tall skyscraper that is the headquarters of CNLBank, Alliance Bankshares before being acquired by the founder of CNL Financial Group. In 2010, its assessed value was $59.6 million.The complex is also home to Orlando's current city hall, which was built after in the old one was demolished in the same area. The demolition was used in the movie Lethal Weapon 3.

Orlando City Hall is the headquarters of the City of Orlando government. The downtown city hall is a 9 floor, postmodern building constructed by Lincoln Property Company and completed in 1992. The building is located in downtown Orlando at the CNL Center City Commons building complex, on the corner of South Orange Avenue and South Street. Construction of the $32 million city hall was overseen by assistant city attorney Lew Oliver and was financed with revenue bonds.The previous eight-story city hall building was blown up in the opening scene of Lethal Weapon 3.

The American Federal Building, also known as the American Federal Savings and Loan Building, the Coral Gables Building, and the Round Building, was an iconic seven-story office building in downtown Orlando, Florida. The bottom two floors, encircled with a cast concrete brise soleil comprise the original building, were completed in 1963. The building's unique architecture and history have inspired efforts to preserve it from demolition.