Arcana Bar and Lounge

Boxer's Ringside, sometimes simply called Ringside, was an LGBTQ bar and music venue in Durham, North Carolina. The first location, known as Boxer's, opened in 1989 and was located on NC 15-501. The second location, 308 W Main Street, was in the city's downtown district.

Novus is a 27-story mixed-use tower under construction at 400 West Main Street in Downtown Durham, North Carolina. Expected to open in 2024, the building site is the former location of the South Bank building.

The Durham Arts Council Building is a cultural center located in downtown Durham, North Carolina within the Downtown Durham Historic District, however it is classified as a noncontributing building.

The American Tobacco Historic District is a historic tobacco factory complex and national historic district located in Durham, Durham County, North Carolina. The district encompasses 14 contributing buildings and three contributing structures built by the American Tobacco Company and its predecessors and successors from 1874 to the 1950s. Located in the district is the separately listed Italianate style W. T. Blackwell and Company building (1874-1880, c. 1904). Other notable contributing resources are the Romanesque Revival style Hill Warehouse (1900), Washington Warehouse (1902–07), the Lucky Strike Building (1901–02), and Reed Warehouse; Noell Building (c. 1930); Power Plant and Engine House (1929–39); and the Art Moderne style Fowler (1939) Strickland (1946) and Crowe (1953) buildings.It was listed on the National Register of Historic Places in 2000 as the American Tobacco Company Manufacturing Plant.

The Hill Building is a 17-story modernistic skyscraper located in Durham, North Carolina. Built in 1935–1937, the Hill Building was designed by New York City architecture firm Shreve, Lamb & Harmon, best known for the design of the Empire State Building. Named for John Sprunt Hill, and built to house the Durham Bank & Trust Company, the building is outfitted with Art Deco ornamentation, interior fluted doors and an exquisitely crafted letter box. The building is in the heart of downtown Durham, located at the intersection of Main and Corcoran Streets. The Hill building was home to Durham Bank & Trust and its successor, Central Carolina Bank and Trust, from 1937 until its 2005 purchase by SunTrust Banks, which had its local headquarters in the building until 2006.Greenfire Real Estate Holdings, which bought the Hill Building in 2006, successfully renovated the building into a 165-room luxury hotel. The city of Durham voted to add $4.2 million after a September 20, 2010 public hearing regarding this plan, and Durham County voted to add $1 million. Greenfire hoped historic tax credits would provide $11 million, and other tax credits would add $4 million.In February 2013, Greenfire formed a joint venture with Kentucky-based hotel operator 21C Museum Hotels. Construction began in late July 2013 and was completed in 2015. Skanska was in charge of the construction project in partnership with 21c Museum Hotels. The renovation also includes a plan for a contemporary art museum, upscale restaurants, bar and ballroom. The museum is open 24 hours per day and offers free admission. An estimated $48 million was spent to complete the entire renovation for the Hill Building. The hotel itself was inducted into Historic Hotels of America, the official program of the National Trust for Historic Preservation, in 2019.

The Museum of Durham History is a history museum in downtown Durham, North Carolina. The building was formerly a railroad and bus depot.

The City View Building, also known as 123 West Main Street and formerly known as the First National Bank of Durham, is a historic skyscraper in the Downtown Historic District in Durham, North Carolina. Since 2001, it has housed the national headquarters of the Center for Community Self-Help.

One City Center is a 27-story mixed-use tower located at 110 Corcoran Street in Downtown Durham, North Carolina, in the United States. One City Center is the tallest building in downtown Durham, and the second tallest in Durham behind University Tower. Completed in 2018, One City Center is partially leased to Duke University and WeWork.

The Pinhook is an LGBTQ-owned music venue in Durham, North Carolina. It is located on the first floor of 117 West Main Street in the Downtown Durham Historic District.

The Carolina Theatre is a performing arts and cinema complex in downtown Durham, North Carolina. The facility is operated by a nonprofit organization named The Carolina Theatre of Durham, Inc. under a management agreement with the City of Durham, which owns the complex.

W.T. Blackwell & Co. Tobacco was a tobacco manufacturer in Durham, North Carolina. It was best known as the original producer of Bull Durham Tobacco, the first nationally marketed brand of tobacco products in the United States. The Blackwell tobacco factory in Durham, built in 1874, was declared a National Historic Landmark in 1977. It is included in the American Tobacco Company Manufacturing Plant historic district, and is now occupied by apartments.

Durham station is an Amtrak station located in Durham, North Carolina. It is served by two passenger trains: the Carolinian and the Piedmont. The street address is 601 West Main Street and is located in West Village in downtown Durham. The station is open from 6:30am to 9:00pm daily. There is free, unattended parking at the station. The station is located in the Walker Warehouse building of the former Liggett and Myers tobacco complex. It opened on July 8, 2009. From 1996 to 2009, the Carolinian and Piedmont stopped at an "Amshack" modular station across the street from the warehouse. The platform itself dates from 1990, when the Carolinian began service; passengers used a heated shelter until the "Amshack" was built in 1996. The historic warehouse is a brick structure erected in 1897 by the American Tobacco Company trust. Included in the Bright Leaf National Register Historic District, the building is marked by impressive decorative brickwork such as corbeled pendants and mousetoothing at the cornice and parapet. The station was a joint venture of the North Carolina Department of Transportation (NCDOT) and the city of Durham. The former entered into an agreement with developer Blue Devil Partners to lease and up-fit one third of the Walker Warehouse, while the city was responsible for 25 percent of the lease costs.The station is frequently used by students at nearby Duke University. Until the Hillsborough station opens, it will also be the nearest station to the University of North Carolina at Chapel Hill.