Corpus Christi Church (Columbus, Ohio)

Southern Orchards is an established neighborhood on the near south side of Columbus, Ohio. It is located immediately southeast of downtown and is the 23rd most walkable neighborhood in Columbus with 3,538 residents. The neighborhood is the target of revitalization and beautification largely due to its anchor institution Nationwide Children's Hospital and a renewed interest in urban living in the city's core. Since 2008, more than 90 properties have been improved through the hospital’s Healthy Homes program and continued revitalization is occurring along the major streets of Livingston and Parsons Avenues as the city moves to reconnect downtown to its surrounding neighborhoods.

The Edward V. Rickenbacker House is a historic house in the Driving Park neighborhood of Columbus, Ohio. Built in 1895, it was the childhood home of Eddie Rickenbacker (1890–1973), who at various times in his life was a flying ace, Medal of Honor recipient, race car driver and a pioneer in air transportation. The house was designated a National Historic Landmark in 1976.

Old Oaks Historic District, or Old Oaks, is a neighborhood just south and east of downtown Columbus, Ohio and is an example of a streetcar suburb in the city.

Saint John the Evangelist Church was a Catholic church of the Diocese of Columbus located on the Near East side of Columbus, Ohio, United States. The initially German-American congregation was founded in 1897, and the High Gothic church building was completed the following year. In 1979, neighboring Holy Rosary Church was merged into the parish, forming the Community of Holy Rosary-St. John and within the decade was 70% black. The merged community was again merged into Saint Dominic Church in 2024. While all Masses for the merged parish are hosted at St. Dominic, the St. John campus continues to host a food bank, learning center and a health clinic sponsored by the Sovereign Military Order of Malta. Columbus Landmarks designated the complex as one of its "most endangered" sites the year of its merger and closure.

South High School is a public high school located on the south side of Columbus, Ohio. It was opened in 1900 as the fourth Columbus City Schools high school at 345 Deshler Avenue. The current building was opened March 31, 1924. The Charles S. Barrett Building at 345 E. Deshler Ave (named for that building's first principal in 1924 when it was reutilized as a junior high school) opened September 1900. Prior to that in 1895-1897 South High School utilized part of the Ohio Avenue Elementary School. In 1897 it was decided that the building was too far east for its name; the south side students were returned to the Central High School building at 6th & Broad Streets, and the building process began on the Deshler Street Building. It was known as South Urban Academy for a short time. The school is located at 1160 Ann Street. The mascot for South High School is the Bulldog. The school was remodeled in 2009 and classes were being held in the Barrett Building, the original South High School. The remodel was complete and classes resumed at the current Ann Street building in the summer of 2010.

Two Dollar Radio Headquarters (HQ) is an independent bookstore, performance and event space, bar, coffeehouse, and a counter-service vegan café located in the South Side neighborhood of Ganthers Place within Thurman Square in Columbus, Ohio. It is locally owned and operated by Eric Obenauf — publisher of the indie press also based in Columbus, Ohio, Two Dollar Radio — and Brett Gregory, with Eliza Wood-Obenauf, and opened in September 2017. As a bookstore, they carry a curated selection of independently published literature, as well as their own Two Dollar Radio books.The café has a regular menu that uses home-made vegan meats, cheeses, and sauces in dips, sandwiches, wraps, pizzas, salads, tacos, desserts, and has a separate weekend brunch menu. They serve tea and coffee drinks using locally roasted and certified organic One Line Coffee, with plant-based milks such as oat, soy, almond, and coconut. Their full bar serves cocktails, wine, and beer, with a rotating selection of draft beer, including local Hoof Hearted Brewing.The venue hosts live cultural events such as author readings, reading series, film screenings, comedy nights, slam poetry open mics, and music from DJs, touring and local bands, and chamber music from local group Chamber Brews.

E.O. Snyder Grocer is a historic building in the Near East Side of Columbus, Ohio. The building was added to the Columbus Register of Historic Properties in 2018.

The Research Institute at Nationwide Children's Hospital is one of America's ten largest free-standing pediatric research centers and works to enhance the health of children by engaging in research.

The McClure-Nesbitt Motor Company is a historic automobile dealership in the South of Main neighborhood of Columbus, Ohio. It was listed on the Columbus Register of Historic Properties in 2017. The building, constructed in 1926, was designed in an elaborate Art Deco style by local architect Ray Sims. The McClure-Nesbitt Motor Company operated out of the building for the next four decades. The building became vacant in 1964, and cycled through ownerships, operating either as a dealership or car repair facility. In 2018, a nonprofit developer began converting the building to hold arts businesses and apartments.

Nationwide Children's Hospital (formerly Columbus Children's Hospital) is a nationally ranked pediatric acute care teaching hospital located in the Southern Orchards neighborhood of Columbus, Ohio. The hospital has 673 pediatric beds and is affiliated with the Ohio State University College of Medicine. The hospital provides comprehensive pediatric specialties and subspecialties to infants, children, teens, and young adults aged 0–21 throughout Ohio and surrounding regions. Nationwide Children's Hospital also sometimes treats adults that require pediatric care. Nationwide Children's Hospital also features an ACS designated Level 1 Pediatric Trauma Center, 1 of 4 in the state. The hospital has affiliations with the nearby Ohio State University Wexner Medical Center. Nationwide Children's Hospital is located on its own campus and has more than 1,379 medical staff members and over 11,909 total employees.In recent years, the hospital has been ranked as one of America's Best Children's Hospitals by U.S. News & World Report and in 2020, the hospital ranked as the 7th best overall children's hospital in the United States. The hospital has also been the recipient of numerous other awards.

Driving Park is an urban residential area on the Near East Side of Columbus, Ohio just south of Interstate 70. Mainly a middle-class, predominantly African American neighborhood, Driving Park and its surrounding neighborhoods consist of an area of 17,730 residents. Driving Park received its name from its historic past as a large racing complex, first for horses and later for automobiles.

Engine House No. 11, also known as the Main Street Engine House, is a former Columbus Fire Department station in the Olde Towne East neighborhood of Columbus, Ohio. The building was constructed from 1896 to 1897, designed in the Romanesque Revival style. The station was decommissioned in 1970.