Roanoke, Virginia

Carilion Roanoke Memorial Hospital (CRMH) is a private teaching hospital in Roanoke, Virginia, USA. With 703 beds, Carilion Roanoke Memorial Hospital is one of the largest hospitals in the state. It is part of Carilion Clinic.The region's only level I trauma center, the hospital operates three medical helicopters (LifeGuard 10, 11, and 12) to provide air ambulance transport, including one in Moneta, one in Christiansburg, and one in Lexington.

The Roanoke Downtown Historic District is a national historic district located in the Downtown Roanoke area of Roanoke, Virginia. It encompasses 122 contributing buildings. It includes a variety of commercial, institutional, social, and governmental buildings and structures from the late 19th century to the mid-20th century. Notable buildings include the Roanoke City Public Library, the YMCA Central Branch Building, First Christian Church (1925), the Central Church of the Brethren (1924), Tomnes Cawley Funeral Home (1928), Thomas B. Mason Building (1961), Peerless Candy Co. (c. 1916), City Hall / Municipal Building (1915), Roanoke Times Building (1892), Anchor Building / Shenandoah Building (1910), Greene Memorial Methodist Church (1890), and United States Post Office and Courthouse (1930). Located in the district are the separately listed Patrick Henry Hotel, Boxley Building, Campbell Avenue Complex Historic District, Colonial National Bank, and First National Bank.It was listed on the National Register of Historic Places in 2002.

Campbell Avenue Complex, also known as the Trinkle Buildings, is a historic commercial block and national historic district located at Roanoke, Virginia. It encompasses five contributing buildings constructed between 1892 and 1909. The contiguous three-story buildings are constructed of brick over stone foundations. The buildings have a horizontal arrangement of windows above first-floor storefronts and include buildings representative of the Beaux Arts and Tudor Revival styles.It was listed on the National Register of Historic Places in 1991.

The Boxley Building is a historic commercial building located in Roanoke, Virginia. It was built in 1922, during a wave of post-World War I construction in the city. The building is eight stories, and follows a pattern set by other skyscrapers of the time in consisting of three sections similar to a classical column. The bottom section, or pedestal, is one story fronted with granite; the middle section, or shaft, consists of the next six stories built with beige enameled brick; the top section, or capital, is the eighth story fronted with richly decorated terra cotta panels topped with a finely detailed copper cornice.The building was commissioned by William Wise Boxley, a local builder and developer who was Roanoke's mayor at the time of construction. Boxley was an influential figure in the city, having played a significant role in the founding of the Shenandoah Life Insurance Company and Colonial American Bank as well as sitting on the boards of both Roanoke College and Virginia Military Institute. Boxley was elected to the Roanoke City Council in 1918, and the following year was appointed the city's first mayor under its new council-manager form of government.: 552  The building's architect was Edward G. Frye, whose firm had previously erected the Roanoke Times building, the city's municipal building, and would complete Roanoke's new market building in the same year as the Boxley.: 500, 504, 586 Boxley's building materials company was one of the original tenants of the building, and remained headquartered there until vacating in 2005. The building was empty from the late-2000s until being purchased by a local developer in 2016. The building's offices were converted into residential space, with the bottom four floors used as dormitory housing for international students of two Roanoke-area parochial schools, and the top four floors converted into luxury apartments.The building was listed on the National Register of Historic Places in 1984, and it is a contributing structure to the Roanoke Downtown Historic District.

First National Bank, also known as People's Federal Building and Liberty Trust Co., is a historic bank and office building located at Roanoke, Virginia. It was built in 1910, and is a seven-story, granite and buff-colored brick building in the French Renaissance style. It features a Roman Ionic columned main entrance and Doric columns in the main banking hall derived from the Temple of Apollo at Delos.The first director of the bank was Tazewell M. Starkey (1829-1901). In 1926 the bank merged with the National Exchange Bank, and took that name. "When the community opened up, there were a lot of members of the Jewish community who have served on various organizations. For instance, Arthur Taubman was on the board of the First National Exchange Bank, on the board of trustees. When that became Dominion Bank, his son, Nicholas F. Taubman, served on that board of trustees, too."It was listed on the National Register of Historic Places in 1982.

Roanoke High School was the first public high school in Roanoke, Virginia. Located at 211-217 Church Ave. S.W., it opened on February 6, 1899. It closed in 1924, replaced by Jefferson High School, and became a school administration building. It was demolished in February 1968 and is now the site of the Noel C. Taylor Municipal Building.

The Patrick Henry Hotel is a Colonial Revival former hotel listed on both the National Register of Historic Places and the Virginia Landmarks Register in Downtown Roanoke, Virginia, United States. Located at 617 South Jefferson Street at the southern end of Downtown, the Patrick Henry was designed by William Lee Stoddart and opened in 1925. The building now serves as apartments, office space, and a restaurant in the former lobby rebranded simply The Patrick Henry. It is located in the Roanoke Downtown Historic District.

Colonial National Bank, also known as the Colonial-American National Bank and the Colonial Arms Building, is a historic bank and office building located at Roanoke, Virginia. It was built in 1926–1927, and is a 12-story, granite and gray-enamel brick building in the Neoclassical style. The building's design echoes that of a classical column; its first three stories compose the base, its shaft is composed of the next seven stories of unornamented brick, and the top two stories of ornamented brick are the capital. The building has a three-story annex built in two stages in 1949 and 1959. The structure was Roanoke's tallest building for almost fifty years. The office building was listed on the National Register of Historic Places in 1983. It has been renovated numerous times, and as of 2018 housed a bank in its lower floors and upscale apartments in the upper portion.

Norfolk and Western Railway Company Historic District is a national historic district located in Roanoke, Virginia. It encompasses three contributing buildings constructed by the Norfolk and Western Railway (N&W). They are the Neoclassical Revival style General Office Building–South (1896, 1903); the Art Deco period General Office Building–North (1931); and the Moderne style Passenger Station (1905, 1949).

Fire Station No. 1 is a former fire station listed on the National Register of Historic Places in the Downtown neighborhood of the independent city of Roanoke, Virginia, United States. Modeled after Philadelphia's Independence Hall, Fire Station No. 1 served as one of the longest continuously operating fire stations in the Commonwealth of Virginia from its completion in 1907 through the opening of a replacement facility in 2007. Designed by the Lynchburg firm of Huggins and Bates, No. 1 still stands as a monument to the civic pride of early Roanoke. It is located in the Roanoke City Market Historic District.

Roanoke station is a train station in Roanoke, Virginia, the current southern terminus of Amtrak's Northeast Regional line. Built in 2017, it follows several other Roanoke passenger stations that operated from the 1850s to 1979. The unstaffed station consists of a single high-level platform with no station building or waiting room available for passengers. All tickets must be purchased in advance; there is no Quik-Trak kiosk at the station.

A statue of Henrietta Lacks was installed in Roanoke, Virginia, in 2024. The artwork was designed by Bryce Cobbs and completed by Lawrence Bechtel.