Grand Rapids and Indiana Railroad Depot (Kalamazoo, Michigan)

For other Haymarket districts see Haymarket District (disambiguation) The Haymarket Historic District is a primarily commercial historic area in Kalamazoo, Michigan. It was listed on the National Register of Historic Places on May 27, 1983. The area includes Michigan Avenue between Portage St. and the Grand Rapids and Indiana railroad line; also 105-141 E. Michigan Avenue. It covers 55 acres and includes 22 buildings. The district's boundaries were increased on May 2, 2011.

The Desenberg Building is a commercial building located at 251 East Michigan Avenue in Kalamazoo, Michigan, within the Haymarket Historic District. It was listed on the National Register of Historic Places in 1979.

Western Michigan University Homer Stryker M.D. School of Medicine (WMed) is a private medical school in Kalamazoo, Michigan. WMed was established in 2012 and confers the Doctor of Medicine (MD) degree, as well as Master of Science in Biomedical Sciences degree and the Master of Science in Medical Engineering degree. WMed is a collaboration between Western Michigan University and Kalamazoo's two teaching hospitals, Ascension Borgess (formerly Borgess Health) and Bronson Healthcare. The inaugural class of 54 students started in August 2014. Although affiliated with the public Western Michigan University, WMed is administratively a private nonprofit school under a separate corporate charter, supported by private gifts, clinical revenue, student tuition, and endowment income. In March 2011, Western Michigan University received a gift of $100 million for the medical school from the Stryker family. In 2018, WMed was granted full accreditation by the Liaison Committee on Medical Education (LCME), graduated its first class of 48 students, and all graduates were matched to residency programs across the nation.

The Bronson Upjohn Building, previously known as the Upjohn Company Office Building or Building 24, is an office building located at 301 John Street in Kalamazoo, Michigan. It was listed on the National Register of Historic Places in 2022.

The Rickman House is an apartment building located at 345 North Burdick in Kalamazoo, Michigan. It was formerly a hotel known as the Rickman Hotel. It was listed on the National Register of Historic Places in 1994.

The Kalamazoo Mall, the first outdoor pedestrian shopping mall in the United States, is a section of Burdick Street in downtown Kalamazoo, Michigan. Built for $60,000 and opened in 1959, the pedestrian mall became the first of several hundred built in the United States. The bold effort to make a downtown street car-free as a spur to urban vitality and a defense against suburbanization drew national attention to Kalamazoo, which was dubbed "Mall City".Initially, two blocks of Burdick Street were closed; a third block was added the following year and a fourth in 1975. In 1998, the southern two blocks were reopened to auto traffic, albeit a single southbound lane only. The two blocks of Burdick from Eleanor Street to W. Michigan Avenue are designated North Kalamazoo Mall; the two blocks south of W. Michigan to W. Lovell Street, South Kalamazoo Mall.

In 1990, the Allied Paper, Inc./Portage Creek/Kalamazoo River in southwestern Michigan was declared by the Environmental Protection Agency (EPA) to be a Superfund site – in other words, an abandoned industrial site containing significant amounts of toxic waste. The EPA and companies responsible for the waste in this area, which includes a three-mile section of Portage Creek as well as part of the Kalamazoo River, into which it flows, are currently involved in an effort to reduce the amount of toxic waste at the site, which is contaminated by PCBs (polychlorinated biphenyls) from paper mills and other factories.

The Kalamazoo Transportation Center is an intermodal complex in downtown Kalamazoo, Michigan. Amtrak and Greyhound provide regular service there. The center is also the major downtown transfer hub for Kalamazoo's Metro Transit bus system. It is served by Amtrak's Blue Water and Wolverine trains and was formerly a stop for the International, which had started in 1982 as joint operation by Via Rail and Amtrak between Chicago and Toronto, was discontinued in 2004. Amtrak does not allow passengers to check luggage at Kalamazoo, but does permit carry-on of up to two suitcases plus "personal items" such as briefcases, purses, laptop bags, and infant gear.

Old Fire House No. 4 is a former fire station located at 526 North Burdick Street in Kalamazoo, Michigan. It was listed on the National Register of Historic Places in 1983.

The Isaac Brown House is a single-family home located at 427 South Burdick Street in Kalamazoo, Michigan. It was listed on the National Register of Historic Places in 1983.

The Masonic Temple in Kalamazoo, Michigan is a building from 1913. It was listed on the National Register of Historic Places in 1980. No lodges currently meet in the building.

The Lawrence and Chapin Building', also known as the Vermeulen Furniture Building, is a commercial building located at 201 North Rose Street in Kalamazoo, Michigan. It was listed on the National Register of Historic Places in 1983.