Haymarket Historic District

The Desenberg Building is a commercial building located at 251 East Michigan Avenue in Kalamazoo, Michigan, within the Haymarket Historic District. It was listed on the National Register of Historic Places in 1979.

The Grand Rapids and Indiana Railroad Depot, is a former railway station in Kalamazoo, Michigan. The original station was built on the site in 1870 by the Grand Rapids and Indiana Railroad. A fire destroyed the building in 1874 and the present structure was built as its replacement. It was later used by the Pennsylvania Railroad and saw passenger service as a stop of the Northern Arrow.The building was designated a Michigan State Historic Site on March 2, 1976. The station building is designed in an Italian Revival style.

Western Michigan University Homer Stryker M.D. School of Medicine (WMed) is a private medical school in Kalamazoo, Michigan. WMed was established in 2012 and confers the Doctor of Medicine (MD) degree, as well as Master of Science in Biomedical Sciences degree and the Master of Science in Medical Engineering degree. WMed is a collaboration between Western Michigan University and Kalamazoo's two teaching hospitals, Ascension Borgess (formerly Borgess Health) and Bronson Healthcare. The inaugural class of 54 students started in August 2014. Although affiliated with the public Western Michigan University, WMed is administratively a private nonprofit school under a separate corporate charter, supported by private gifts, clinical revenue, student tuition, and endowment income. In March 2011, Western Michigan University received a gift of $100 million for the medical school from the Stryker family. In 2018, WMed was granted full accreditation by the Liaison Committee on Medical Education (LCME), graduated its first class of 48 students, and all graduates were matched to residency programs across the nation.

The Bronson Upjohn Building, previously known as the Upjohn Company Office Building or Building 24, is an office building located at 301 John Street in Kalamazoo, Michigan. It was listed on the National Register of Historic Places in 2022.

The Kalamazoo Mall, the first outdoor pedestrian shopping mall in the United States, is a section of Burdick Street in downtown Kalamazoo, Michigan. Built for $60,000 and opened in 1959, the pedestrian mall became the first of several hundred built in the United States. The bold effort to make a downtown street car-free as a spur to urban vitality and a defense against suburbanization drew national attention to Kalamazoo, which was dubbed "Mall City".Initially, two blocks of Burdick Street were closed; a third block was added the following year and a fourth in 1975. In 1998, the southern two blocks were reopened to auto traffic, albeit a single southbound lane only. The two blocks of Burdick from Eleanor Street to W. Michigan Avenue are designated North Kalamazoo Mall; the two blocks south of W. Michigan to W. Lovell Street, South Kalamazoo Mall.

The Rickman House is an apartment building located at 345 North Burdick in Kalamazoo, Michigan. It was formerly a hotel known as the Rickman Hotel. It was listed on the National Register of Historic Places in 1994.

The Masonic Temple in Kalamazoo, Michigan is a building from 1913. It was listed on the National Register of Historic Places in 1980. No lodges currently meet in the building.

The Kalamazoo Transportation Center is an intermodal complex in downtown Kalamazoo, Michigan. Amtrak and Greyhound provide regular service there. The center is also the major downtown transfer hub for Kalamazoo's Metro Transit bus system. It is served by Amtrak's Blue Water and Wolverine trains and was formerly a stop for the International, which had started in 1982 as joint operation by Via Rail and Amtrak between Chicago and Toronto, was discontinued in 2004. Amtrak does not allow passengers to check luggage at Kalamazoo, but does permit carry-on of up to two suitcases plus "personal items" such as briefcases, purses, laptop bags, and infant gear.

The Lawrence and Chapin Building', also known as the Vermeulen Furniture Building, is a commercial building located at 201 North Rose Street in Kalamazoo, Michigan. It was listed on the National Register of Historic Places in 1983.

The Isaac Brown House is a single-family home located at 427 South Burdick Street in Kalamazoo, Michigan. It was listed on the National Register of Historic Places in 1983.

The Kalamazoo Public Library is an independent district library in Kalamazoo, Michigan, that serves about 120,000 people, has a salaried staff of 90, and spends about $10 million annually. The library consists of the central branch downtown, and four branch libraries.

Old Fire House No. 4 is a former fire station located at 526 North Burdick Street in Kalamazoo, Michigan. It was listed on the National Register of Historic Places in 1983.