Senate President Neptali A. Gonzales General Hospital

The National Center for Mental Health (Filipino: Pambansang Sentro ng Pangkaisipang Kalusugan), is a 4,200-bed psychiatric hospital occupying 47 hectares of land in the city of Mandaluyong, Philippines. It is PhilHealth-accredited.

The Correctional Institution for Women (CIW) is a women's prison located in Mandaluyong, Metro Manila, Philippines. The prison is operated by the Bureau of Corrections.The prison first opened on a 18-hectare (44-acre) property on February 14, 1931. Previously women were held at the Old Bilibid Prison.When the Philippines had the death penalty, female inmates condemned to death were held at CIW. Ron Gluckman of Asiaweek described the women's death row as appearing like a secondary school.

Philippine Charity Sweepstakes Office board secretary Wesley Barayuga was killed by an unidentified gunman on July 30, 2020 in Mandaluyong, Metro Manila, Philippines. Barayuga was initially speculated to have been killed due to work-related issues. He was also without evidence, accused of being part of a 'narcolist' created for President Rodrigo Duterte's Philippine drug war. Despite Barayuga's profile as a high-ranking government official and a former police officer, his killing remained a cold case for four years until police officer Santie Mendoza implicated National Police Commission commissioner Edilberto Leonardo and then PCSO general manager Royina Garma of masterminding the killings during a House of Representatives inquiry in September 2024, two years into the presidency of Duterte's successor Bongbong Marcos.

Shaw Boulevard (formerly known as Jose Rizal Boulevard and Pasig Boulevard or commonly known as Crossing) is a 4-8 lane highway connecting the cities of Mandaluyong and Pasig in the Philippines. The boulevard is named after William James Shaw, the founder of the Wack Wack Golf and Country Club in Mandaluyong. The road is one of the major thoroughfares of the Ortigas Center in Mandaluyong and Pasig, housing many shopping malls like the Starmall shopping center and the posh Shangri-La Plaza at the EDSA-Shaw intersection and The Marketplace at the Kalentong-Shaw intersection.It is served by the Shaw Boulevard station of the MRT-3 along EDSA, often called EDSA-Crossing. The entirety of the road is served by bus and jeepney routes that go to and from Quiapo, Santa Mesa, the José Rizal University, EDSA, Ortigas Center, the Pasig Public Market, and Binangonan, Rizal.

The Summit One Tower is an office skyscraper located in Mandaluyong, Philippines. Originally built as a condominium project called Paladium Summit but when the concrete shell was completed the project fell through until a local tycoon bought and converted it into an office tower. Summit One Tower was previously owned and managed by Facilities Incorporated. It is now owned and managed by Summit One Tower Building and Allied Assets, a part of the ATN Group of Companies. The building is registered as an economic zone with the Philippine Economic Zone Authority (PEZA) and its IT locator tenants benefit from government tax incentives. Although there is no sufficient source to confirm is official height, Skyscraperpage's website has an official diagram suggesting its height to be around 200 meters, which is highly dubious.It is also serves as a radio transmitter of the FM radio station 91.5 Win Radio owned by Mabuhay Broadcasting System.

Wack Wack Twin Towers are twin residential towers situated in Mandaluyong, Metro Manila, Philippines. Both of its towers are 30-storeys high with a height of 140 m (459.32 ft). The towers are set in a country park, developed on former grassland. The area is named after the local bird "uwak" (crow).

Rizal Technological University (RTU) is a state university located at Mandaluyong, Philippines. It was established on July 11, 1969, as the College of Rizal, part of the University of Rizal System before it became autonomous in 1975. The state university is also the first educational institution in the country to use cooperative education as a curriculum plan which is recognized by various industries, businesses and agencies all over the country. The university has various different academic fields, and focuses primarily on architecture, engineering, and technology programs. RTU is also one of the first educational institutions in the Philippines to offer degrees in astronomy.

8 Wack Wack Road is a 42-story residential skyscraper in Mandaluyong, Metro Manila, Philippines. The building has a height of 147.14 m (482.74 ft). It is located in Brgy. Wack Wack.

Boni station (also called Boni Avenue station) is a Manila Metro Rail Transit (MRT) station situated on Line 3. It is the eighth station for trains headed to Taft Avenue and the sixth station for trains headed to North Avenue. It is located in Mandaluyong and is named so due to its proximity to Boni Avenue, which is in turn named after the nickname of Bonifacio Javier, a World War II guerilla leader and former mayor of Mandaluyong. It has several restaurants and shops that surround the station, including a public market located across the train station.

Forum Robinsons, formerly called as Robinsons Place Pioneer, was a shopping mall located in Mandaluyong, Metro Manila, Philippines owned and operated by Robinsons Land. The mall opened on November 17, 2004. It is the 18th mall opened by Robinsons and the first mall in Mandaluyong with a gross floor area of 56,000 square meters (600,000 sq ft). The former name Robinsons Place Pioneer was dubbed after its location, Pioneer Street. Back then, the mall was envisioned to become a one stop shop for everyone in Cybergate Complex which was in turn envisioned to become a cyberhub in the city. In 2010, the mall was renamed to its current name to re-position itself as a cyber lifestyle mall focusing on IT products and to align itself with the vision of the Cybergate Complex. The mall closed on April 30, 2022 to give way for its redevelopment works, which was originally set to start on early 2020 but was delayed due to the COVID-19 pandemic in the Philippines. The new complex will feature office towers atop the new mall area.

Shaw Boulevard station (also called Shaw for short) is an elevated Manila Metro Rail Transit (MRT) station situated on Line 3. The station is located in the Mandaluyong portion of Ortigas Center and is named after Shaw Boulevard, since the station lies directly above the boulevard. The station is the seventh station for trains headed to Taft Avenue and North Avenue. Shaw Boulevard station lies at the center of the whole line, with many commuters regarding it as the "central terminal" of the line.

The Jose Fabella Memorial School (Filipino: Pang-alaalang Paaralang Jose Fabella; abbreviated as JFMS and commonly known as Fabella) is a public integrated special school located in Welfareville Compound, Mandaluyong in Metro Manila, Philippines. Founded on December 3, 1925 as the Welfareville School, it is considered as one of the oldest educational institutions in Mandaluyong and is currently one of the four public special schools in the Philippines. It serves as the umbrella organization of 12 special education units located in different parts of Metro Manila and Rizal and offers kindergarten, elementary, secondary (junior and senior high school) and special education to regular students and students with additional needs.