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Gopalapuram is a prime residential locality in Chennai, Tamil Nadu, India. It is surrounded by Royapettah in the North and East, Mylapore in the South-East, Teynampet in the South and Thousand Lights in the West. It is located 17 km (11 mi) from the Chennai International Airport and 3 km (1.9 mi) from Chennai Central railway station. It is located in between Dr. Radhakrishnan Salai and Anna Salai. Avvai Shanmugam Road passes through Gopalapuram, dividing it into North Gopalapuram and South Gopalapuram. Gopalapuram comes under Chennai Central Lok Sabha constituency.

National Public School (NPS), in Gopalapuram, Chennai, India, is run by the Citizens Education Society. It was founded in 1970 by Dr.K.P. Gopalkrishna and is affiliated to the CBSE.

DAV Boys Senior Secondary School is a senior secondary high school located in Gopalapuram, a central part of Chennai, India. It is affiliated to the Central Board of Secondary Education. The school is noted for its high results in the CBSE Class 12 Board Exams and has been ranked among the best in the country over the years, especially in academics. In the past, the school has been ranked among the top three schools in India in the CBSE Class 12th Board Exam Results . The magazines Outlook and Education World rated the school as the best in Tamil Nadu. Shri Ravi Malhotra is incumbent President of the Board Of Management. The Principal is Mrs.Chitra R Raghavan who replaced Shanthy Asokan in 2020.

The New College (Tamil: புதுக்கல்லூரி) is an institution of higher education in Chennai, Tamil Nadu. Established in 1951, the institution is one of the affiliated colleges of the University of Madras, with autonomous status. The college was established by the Muslim Educational Association of Southern India (MEASI) to meet the educational requirements of the Muslim students in South India. The maximum 90% of strength in college is Muslim students.

The Savera is an 11-storied four-star hotel located in Mylapore, Chennai, India.

Madras Music Academy is one of the earliest established music academies in South India. Before the concept of infrastructure was introduced to India in the early 1920s, it was a gathering for elite musicians simply called (and is still more commonly referred to as) Music Academy (Tamil: சங்கீத வித்வத் சபை, sangeetha vidhwadh sabai) It plays an important role in encouraging and promoting primarily the Carnatic Music Indian art form. It played a vital role in the revival of the Indian classical dance form of Bharatnatyam in the 1930s when it faced near extinction due to a negative connotation caused by conservative societal standards.They also run a music school called the Teachers college of Carnatic Music which has many eminent musicians on its faculty. Musicians such as Tiger Varadachariar, Appa Iyer, Valadi Krishnaiyer and Mudicondan Venkatarama Iyer adorned the chair of Principal of the Teacher's College.

Adarsh Vidyalaya Higher Secondary School is a Matriculation School by the Punjab Association for girls. It is in Royapettah, Chennai, India. The school was founded by Padmashri. P.N. Dhawan, Mrs. Visharda Hoon was the first principal. Mrs Vasanthalakshmi and Mrs Radha Ravangi were subsequent principals. Its other branches are Adarsh Vidyalaya Branch School, Adarsh Higher Secondary School, Maloney Road (Closed in 2007), Gill Adarsh Matriculation Higher Secondary School, MGR Adarsh Public Matric Higher Secondary School, Padma Adarsh Higher Secondary School and Anna Adarsh Matric Higher Secondary School.

The Madras Diabetes Research Foundation (MDRF) is a medical research organization located in Gopalapuram, Chennai. MDRF was established in 1996 by an eminent diabetologist, Dr. V. Mohan.

Chemplast Sanmar Limited is an Indian chemical company. It is a major manufacturer of PVC resins, chlorochemicals and piping systems.

The New Woodlands Hotel is an Udupi-style vegetarian restaurant in Chennai, India. Established in 1938 by Kadandale Krishna Rao, it is considered to be a pioneer in popularizing Udupi cuisine in the city. Since then, a large number of imitations and namesake Woodlands hotels have been established in various parts of Chennai.

WelcomHotel Chennai, formerly known as the Chola Sheraton and later the My Fortune Chennai, is a five-star luxury hotel located at Cathedral Road in Chennai, India. Opened in 1975 as the "Chola Hotel", it is one of the first five-star hotels in Chennai City. It is also the first hotel to be launched under ITC's brand "My Fortune". WelcomHotel Chennai is an ISO 14001–certified hotel for its environment management systems. It is one of the hotels licensed by ITC Hotels Limited.

Royapettah is a neighbourhood of Chennai, India.