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Veselka is a Ukrainian restaurant at 144 Second Avenue in the East Village neighborhood of Manhattan in New York City. It was established in 1954 by Wolodymyr Darmochwal (Ukr. Володимир Дармохвал) and his wife, Olha Darmochwal (Ukr. Ольга Дармохвал), post–World War II Ukrainian refugees. Veselka is one of the last of many Slavic restaurants that once proliferated the neighborhood. A cookbook, published in October 2009 by St. Martin’s Press, highlights more than 120 of the restaurant’s Eastern European recipes.A sister restaurant, Veselka Essex, opened in Essex Crossing in 2019. Another restaurant, on East 1st Street and Bowery, opened in November 2011 and closed in 2013.

St. Mark's Playhouse at 133 Second Avenue in the East Village of Manhattan, New York City, was an Off-Off-Broadway theater notable for presenting the Negro Ensemble Company's production of The First Breeze of Summer by Leslie Lee, which premiered on March 2, 1975, before transferring to Broadway on June 10, where it played through July 20, 1975. St. Mark's Playhouse also showed French playwright Jean Genet's first American performance of his play The Blacks. The theatre was founded by Lynn Michaels and Harry Baum.

The Second Avenue Deli (also known as 2nd Ave Deli) is a certified-kosher Jewish delicatessen in Manhattan, New York City. In December 2007, it relocated to 162 East 33rd Street (between Lexington Avenue and Third Avenue) in Murray Hill. In August 2011, it opened a second branch at 1442 First Avenue (East 75th Street) on the Upper East Side. In November 2017, it opened a cocktail lounge called 2nd Floor above its Upper East Side branch.In 1998, the deli won an America’s Classic Award by the James Beard Foundation.

The Orpheum Theatre, formerly Player's Theatre, is a 299-seat off-Broadway theatre on Second Avenue near the corner of St. Marks Place in the East Village neighborhood of lower Manhattan, New York City. It has been the home of the New York production of Stomp since it opened in 1994, with over 10,000 performances of the show having taken place there. There may have been a concert garden on the site as early as the 1880s, but there was a theatre there by 1904. During the heyday of Yiddish theatre in the Yiddish Theater District in Manhattan, the venue was the Player's Theatre, and was part of the "Jewish Rialto" along Second Avenue. By the 1920s, the theatre was exhibiting films, but was converted back to dramatic use in 1958, with the first production, Little Mary Sunshine, opening in November 1959.Significant productions include the revival and revamping of Cole Porter's musical Anything Goes in 1962, Your Own Thing in 1968, The Me Nobody Knows in 1970, The Cocktail Party in 1980, Key Exchange in 1981, Broken Toys! in 1981, Little Shop of Horrors in 1982, Sandra Bernhard's Without You I'm Nothing in 1988, The Lady in Question in 1989, Eric Bogosian's Sex, Drugs, Rock & Roll in 1990, John Leguizamo's Mambo Mouth in 1991, and David Mamet's Oleanna in 1992.The theatre is owned by Liberty Theatres, who also own Minetta Lane Theatre.

Gem Spa was a newspaper stand and candy store located on the corner of St. Mark's Place and Second Avenue in the East Village neighborhood of Manhattan, New York City. It opened under another name in the 1920s, and was renamed in 1957. It was open 24 hours a day, and was known for being commonly considered to be the birthplace of the authentic New York City-style egg cream, which its awning described as "New York's Best."Often referred to as a bodega, in the 1950s, Gem Spa was a gathering place for beats, and in the 1960s it was a hippie hangout, known for selling a wide selection of underground newspapers. New York Magazine named it the best newsstand in the East Village in 2001.On May 7, 2020, owner Parul Patel announced that the physical store would not re-open due to the impact of the COVID-19 pandemic and rent increases, despite community efforts and a social media campaign to keep it open.The building in which Gem Spa was located, 131 Second Avenue, or 36 St. Marks Place, was built in 1898-1900 and was designed by Louis F. Heinecke in the Renaissance Revival style. It is located within the East Village/Lower East Side Historic District, which was created in October 2012.

The Ottendorfer Public Library and Stuyvesant Polyclinic Hospital are a pair of historic buildings at 135 and 137 Second Avenue in the East Village neighborhood of Manhattan in New York City. The buildings house the Ottendorfer Branch of the New York Public Library, as well as the women's workspace The Wing within the former Stuyvesant Polyclinic hospital. The buildings were jointly designed by German-born architect William Schickel in the neo-Italian Renaissance style. Both structures are three stories tall with a facade of Philadelphia pressed brick facades ornamented in terracotta. The hospital building features terracotta busts of several notable medical professionals. The structures were erected in 1883–84 following a donation by philanthropists Oswald Ottendorfer and Anna Ottendorfer. The library was the second branch of the New York Free Circulating Library, while the hospital was affiliated with the German Hospital uptown, now Lenox Hill Hospital. Both structures served the Little Germany enclave of Lower Manhattan. The hospital was sold in 1906 to another medical charity, the German Polyklinik; the name was changed to Stuyvesant Polyclinic in the 1910s. The buildings were restored numerous times in their history. The structures received three separate New York City landmark designations in 1976, 1977, and 1981, and were added to the National Register of Historic Places in 1979.

Club 57 was a nightclub located at 57 St. Mark's Place in the East Village, New York City during the late 1970s and early 1980s. It was originally founded by Stanley Zbigniew Strychacki and enhanced by nightclub performer Ann Magnuson, Susan Hannaford, and poet Tom Scully. It was a hangout and venue for performance and visual artists and musicians, including The Cramps, Madonna, Keith Haring, Cyndi Lauper, Charles Busch, Klaus Nomi, The B-52s, RuPaul, Futura 2000, Tron von Hollywood, Kenny Scharf, Frank Holliday, John Sex, Wendy Wild, The Fall, April Palmieri, Robert Carrithers, The Fleshtones, The Fuzztones, Joey Arias, Lypsinka, Michael Musto, Marc Shaiman, Scott Wittman, Fab Five Freddy, Jacek Tylicki, and to a lesser extent, Jean-Michel Basquiat.

B&H Dairy is a kosher restaurant or luncheonette in the East Village of Manhattan in New York City. The original owners, Abie Bergson and Jack Heller, later Sol Hausman, opened it in 1938 when the area was known for the Yiddish Theatre District. Bergson was an aspiring actor, and Molly Picon and Maurice Schwartz were patrons. Bergson sold the luncheonette in the 1970s and it went bankrupt in 1978. Bob Sherman, a partner in a construction firm, bought it. A 1940s style lunch counter B&H serves cheese blintzes with sour cream, borscht, matzo brei, and other kosher dairy Jewish cuisine. It is owned and operated by an Egyptian Muslim and Catholic Polish couple, Fawzy and Alexandra Abdelwahed. It was closed for a time due to a gas explosion and a fire but reopened. It was noted in an interview by Lily Tomlin. Chloë Sevigny is also a patron of the establishment.

Abe Lebewohl Park is a public park in the East Village neighborhood of Manhattan in New York City, in front of the St. Mark’s Church in-the-Bowery where East 12th Street, Second Avenue, and Stuyvesant Street meet. The park is named after Abe Lebewohl, a local who owned the Second Avenue Deli, which was formerly located across the street from the park. It contains a small seating area as well as a Ukrainian-American World War II memorial.

Hebrew National Orphan Home (HNOH) was an orphanage in Manhattan in New York City. It was founded on December 5, 1912, when a group raised $64 toward establishing a Jewish orthodox home for the care of orphaned and destitute Jewish boys. On October 14, 1913, a committee of the Bessarabian Verband, a group of Romanian Jews, paid the first installment of $400 for the premises at 57 East 7th Street between First and Second Avenues – in what was then the Lower East Side and is now the East Village. On June 7, 1914 HNOH House officially opened with accommodations for 50 boys. Later, the home bought a second tenement that backed onto the original building, creating an enclosed courtyard, and doubling the home's capacity to 100.On July 15, 1919 a facility on Tuckahoe Road in Yonkers, New York was purchased for $300,000, and the home moved there on July 26, 1920. In 1947, it changed its name to Homecrest then it merged with the Gustave Hartman home for children in 1956 under the name of Hartman-Homecrest and in early 1962 Hartman-Homecrest was merged into the Jewish Child Care Association (JCCA) of New York and the name HNOH after 60 years, was no longer used.

The Gate Theatre was an Off-Broadway theatre in New York City that was active during the 1950s through 1970s. Located at 162 Second Avenue in the East Village, the theatre was founded in 1957 by Lily Turner. It closed in the early 1970s.

The Slovenian Church of St. Cyril in New York is a historic religious institution located in the East Village neighborhood of Manhattan and Slovenia's cultural center in New York City. It holds historical significance for Slovenia and its people, having played a pivotal role for over a century, including during Slovenia's independence. It is currently the only place in New York where Slovenians meet. Since no Slovenian businesses have offices in New York, apart from the country's delegation to the United Nations, it stands as the city's sole Slovenian location.This church has served as a focal point for the Slovenian immigrant community in New York City for many years, offering a place of worship and cultural connection.