Duff Building

The Grow Block is a commercial building located at 120-122 West Exchange Street in Owosso, Michigan. It was listed on the National Register of Historic Places in 1985.

The Owosso Downtown Historic District is a substantially commercial historic district, located in downtown Owosso, Michigan, roughly bounded by the Shiawassee River, Comstock Street, Water Street, Park Street, and Mason Street. The district was listed on the National Register of Historic Places in 2014.

The Oliver Street Historic District is a primarily residential historic district, located along Oliver Street between Third and Oak Street, as well as some adjacent sections of Williams and Goodhue Streets, in Owosso, Michigan. It was listed on the National Register of Historic Places in 1980.

The Colin McCormick House is a historical house in Owosso, Michigan, designed by Edger Ingersoll, and is notable for its size. It has had only 4 owners in its more than 120-year history. The last member of the McCormick family died in the house at 107 years of age. Edger Ingersoll incorporated features like the slate roof, crocheted roof ridging, hipped roof, scalloped trim, and more. It lies at 220 E. Exchange. The house was added to the National Register of Historic Places in 1980.

The Lincoln School was built in 1915 in the Classical Revival style. The school was added to the National Register of Historic Places in August 2016. The building now houses the Lincoln House Apartments.

Curwood Castle is a small castle, now a museum, located in Owosso, Michigan, built by the author James Oliver Curwood.

The Old Miller Hospital was constructed as a single-family home located at 121 Michigan Avenue in Owosso, Michigan; it was later converted to a private hospital. It was listed on the National Register of Historic Places in 1980.

The Curwood Festival is a celebration of the American novelist James Oliver Curwood in Owosso, Michigan. Many of his novels were written in Curwood Castle on the banks of the Shiawassee River.

The Elias Comstock Cabin is a single-family home located at the corner of Curwood Castle Drive and John Street in Owosso, Michigan. It was listed on the National Register of Historic Places in 1980. It is the oldest residence still extant in the City of Owosso.

The George Pardee House is a single-family home located at 603 North Ball Street in Owosso, Michigan. It was listed on the National Register of Historic Places in 1980.

The Christian-Ellis House is a single-family home in Owosso, Michigan, built in 1895. It was listed on the National Register of Historic Places in 1980.

The Nathan Ayres House is a single-family home located at 604 North Water Street in Owosso, Michigan. It was added to the National Register of Historic Places in 1980.