The 2i's Coffee Bar

Comptons of Soho is a gay pub in London. Situated at 51–53 Old Compton Street in the heart of Soho's 'Gay village', Comptons has been an integral part of London's gay scene since June 1986.

Heavenly Recordings is a London-based independent record label founded by Jeff Barrett in 1990. Heavenly released the first albums from Saint Etienne, Beth Orton and Doves, and early singles by Manic Street Preachers. Current Heavenly artists include Stealing Sheep, Mattiel, The Orielles, Confidence Man, audiobooks, Pip Blom, H. Hawkline, King Gizzard & the Lizard Wizard, Gwenno Saunders, Amber Arcades, Working Men's Club, Katy J Pearson and CHAI. Heavenly won Independent Label of the Year at the 2015 Music Week Awards. Other achievements include a Mercury Prize nomination for Saint Etienne's debut album Foxbase Alpha and three Number 1 albums with Doves. It is considered a key British indie record label, alongside Factory, Creation, Rough Trade, Mute, Ninja Tune and Domino.

Saint Anne's Church serves in the Church of England the Soho section of London. It was consecrated on 21 March 1686 by Bishop Henry Compton as the parish church of the new civil and ecclesiastical parish of St Anne, created from part of the parish of St Martin in the Fields. The church is under the Deanery of Westminster (St Margaret) in the Diocese of London. Parts of its churchyard around its west including tower are now the public park of St Anne's Gardens, accessed from the Shaftesbury Avenue end of Wardour Street. The church is accessed via a gate at that end of Dean Street. The parish, having spawned new churches to Saints Thomas and Peter in the era of compulsory church attendance, reconsolidated on Saint Anne's in 1945.

St Anne's Churchyard, also known as St Anne's Gardens, is a public park on Wardour Street in Soho, London. Formerly the churchyard of St Anne's, Soho, it was closed to burials in 1853. It rises 6 ft above the pavement, because of the 13,000 burials within it. It was laid out as a garden by the landscape gardener Fanny Wilkinson on behalf of the Metropolitan Public Gardens Association in 1891. It was opened to the public by Lady Hobhouse in 1892. The London plane trees remain a notable feature of the garden. It is managed by Westminster City Council and has received the Green Flag Award.War memorials to WWI and WWII are located in the churchyard on the wall of the church tower. The WWII memorial was only installed in 2012. There are a small number of memorials remaining within the churchyard, including the German adventurer Theodore von Neuhoff, who was briefly King of Corsica in 1736, and the essayist William Hazlitt, whose gravestone was restored in 2003.The gardens contain a memorial to the victims of the 1999 Admiral Duncan pub bombing. There are three art installations, all of which serve practical purposes: "Wall of Light" (an illuminated security fence), "Art Loo" (a WC with art displays) and "Table" (a monumentally-sized picnic table).

The London Blues and Barrelhouse Club ran between 1957 and 1961 at the Round House public house at the junction of Wardour Street and Brewer Street in Soho, London. Established by Cyril Davies and Alexis Korner, it hosted many visiting American blues performers and was an important catalyst in developing British blues music, R&B, and ultimately British rock music.

The Rosy Wilde gallery was an artist-run project space, established in 2003 by British artist Stella Vine in a former butcher's shop below her house in east London, to showcase work by emerging artists. The gallery was not making money and Vine was expecting bailiffs, when one of her paintings of Diana, Princess of Wales, was bought by art collector Charles Saatchi to star in his New Blood show. This solved Vine's financial problems. The gallery was sold at auction in October 2004 and, in 2006, Vine opened a gallery of the same name in central London's Soho district. It closed some time later.

The Admiral Duncan is a public house in Old Compton Street, Soho in central London that is well known as one of Soho's oldest gay pubs. In 1999, the pub was bombed by neo-Nazi David Copeland, resulting in three people being killed and 83 being injured.

The Sondheim Theatre (formerly the Queen's Theatre) is a West End theatre located in Shaftesbury Avenue on the corner of Wardour Street in the City of Westminster, London. It opened as the Queen's Theatre on 8 October 1907, as a twin to the neighbouring Hicks Theatre (now the Gielgud Theatre) which had opened ten months earlier. Both theatres were designed by W. G. R. Sprague. The theatre was Grade II listed by English Heritage in June 1972.In 2019 the theatre's name was changed from the Queen's to the Sondheim Theatre (after Stephen Sondheim) after a 20 week refurbishment. The theatre reopened on 18 December 2019.

Café Monico was a restaurant on London's Shaftesbury Avenue. It was originally established in 1877 at 15 Tichborne Street in 1877 by the brothers Giacomo and Battista Monico.The first World Weightlifting Championships, then known as the International Amateur Weight Lifting Championship, was held at the Café Monico in 1891, and the Climbers' Club was formed there in 1897.The banquet for the London 1899 chess tournament took place there.After some time as the nightclub Avalon, a refurbished Cafe Monico reopened under the new ownership of Soho House in April 2016. It became a two-floor restaurant serving European dishes under the supervision of consultant chef Rowley Leigh.The restaurant closed permanently in 2021.

The Algerian Coffee Stores is a coffee shop in Old Compton Street in the Soho neighborhood of London, England. Founded in 1887, it is the oldest coffee shop in London.It was founded in 1887 by M. Siari, an Algerian, at number 52 Old Compton Street. It is still known as among the world's best leading suppliers of tea and coffee, and remains up to now one of the oldest shops in the street. It is situated next to the famous Admiral Duncan pub, which has been trading since at least 1832.

56 Dean Street, based in Dean Street in London's Soho district, is the city's largest sexual health clinic. Part of the Chelsea and Westminster Hospital NHS Foundation Trust, it also has a second branch, Dean Street Express, at 34 Dean Street, which offers a fast-turnaround testing service. As of 2017, the clinic was the largest HIV clinic in Europe. In addition to its specialism in HIV infection and other sexually transmitted diseases, it also offers general sexual health care services, including contraception. The clinic also runs TransPlus - the UK’s first integrated NHS gender dysphoria, sexual health and HIV service. 56 Dean Street is recognised internationally for its innovation, particularly in regard to its engagement of London's higher-risk communities as well as HIV epidemic management. HIV combination prevention is the multi-factoral approach to addressing the HIV epidemic. It includes; engagement of high risk communities in regular HIV testing condom awareness and use easy access to HIV-PEP (Post-Exposure Prophylaxis) quick-start HIV treatment; once diagnosed HIV positive, patients are prescribed HIV ART (Anti-Retroviral Therapy) within days after diagnosis, quickening their journey to an uninfectious status, to reduce the number of infectious people within communities, and slowing the spread of infection in communities. This is called Treatment as Prevention PrEP, which can protect HIV negative people from HIV infection. The clinic has made the provision of pre-exposure prophylaxis (PrEP) a priority. Behavioral advice, support and psychosocial interventions (eg, chemsex support, sexual wellbeing information education, support community awareness of all the above.with the result that new HIV infection rates in London have dropped dramatically since the introduction of these interventions.

Meard Street is a street in Soho, London. It runs roughly east–west (properly, east-northeast to west-southwest, as elsewhere in Soho), between Wardour Street to the west and Dean Street to the east. It is in two sections, with a slight bend in the middle: the west half is pedestrianised, while the east half is a narrow, single-lane road. The street is named after John Meard, the younger, a carpenter, later esquire, who developed it in the 1720s and 1730s.It is prominently featured in photographs and postcards for the tourist trade, due to the pun with French: merde and Italian: merda ("shit"). 15 Meard Street served as the exterior of the home occupied by characters played by Ian McKellen and Derek Jacobi in the 2013–16 ITV sitcom Vicious.