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Midtown is a loosely defined region in south Minneapolis, Minnesota, United States. There are no hard-set boundaries to the midtown area, but it is generally agreed to include the area in the vicinity of Lake Street between Interstate 35W and Hiawatha Avenue. Lake Street is the border between the Phillips and Powderhorn communities of Minneapolis. Lake Street/Midtown LRT Station, with service on the METRO Blue Line, is located on the eastern edge of the area. The midtown area was historically known as being somewhat of a run-down area. However, in the past decade or two, there has been a large revitalization effort along Lake Street, driven largely by an insurgence of new Latino and Northeast African businesses.Near the intersection of Chicago Avenue and Lake Street is the Midtown Exchange building, which was a Sears department store and mail-order catalog facility until the company closed it in 1994. After sitting vacant for a decade, the building was fully redeveloped. It features office space, residential units, and the Midtown Global Market, a large marketplace featuring an ethnically diverse variety of restaurants, grocers, and retailers. Other indoor markets that have opened in the midtown area include the Mercado Central (at Bloomington Ave and Lake St), which houses numerous Latino businesses, and the Lake Plaza (at 3rd Ave and Lake St), which houses Somali and Latino businesses. As of January 2009, a new market has opened in the former True Value Hardware site at the Hi-Lake Shopping Center (21st Ave and Lake St), housing Somali businesses. At 22nd Ave and Lake Street (in the parking lot of Anishinabe Academy School) the Midtown Farmers' Market operates on Tuesdays and Saturdays from late spring to early autumn. Many places and groups use the "midtown" descriptor in their names. Examples include: The Midtown Greenway, a major bicycling and walking trail paralleling Lake Street The Midtown Exchange and the Midtown Global Market The Midtown Freewheel Bike Center, a bike shop on the Midtown Greenway The Midtown YWCA (Lake Street and 22nd Ave) The Lake Street/Midtown light rail station on the METRO Blue Line The Sheraton Minneapolis Midtown Hotel The Midtown Church Project, a church plant utilizing principles of self-organization and community development

In the Heart of the Beast Puppet and Mask Theatre (also known as Heart of the Beast or HOBT) is a puppet company and nonprofit organization from Minneapolis, Minnesota. The company has written and performed scores of full-length puppet plays, performed throughout the US, Canada, Korea, and Haiti and toured the Mississippi River from end to end. The theatre is best known for sponsoring the annual May Day Parade and Ceremony that is seen by as many as 50,000 people each year.

The Midtown Exchange is a historic structure and mixed-use building located in the Midtown neighborhood of Minneapolis, Minnesota, United States. It is the second-largest building in Minnesota in terms of leasable space, after the Mall of America. It was built in 1928 as a retail and mail-order catalog facility for Sears, which occupied it until 1994. It lay vacant until 2005, when it was transformed into multipurpose commercial space. The building is listed on the National Register of Historic Places as the Sears, Roebuck and Company Mail-Order Warehouse and Retail Store.

Allina Health is a not-for-profit health care system based in Minneapolis, Minnesota, United States. Allina Health owns or operates 12 hospitals and more than 90 clinics throughout Minnesota and western Wisconsin. In addition Allina Medical Transportation covers 8 regions and over 80 communities providing medical dispatch, 911 pre-arrival instructions, and emergency and non-emergency ambulance response.

East Phillips is a neighborhood within the Phillips community in Minneapolis. Its northern boundary runs along East 24th Street from Bloomington Avenue to 17th Avenue South, then runs along East 22nd Street from 17th Avenue South to Little Earth Trail and Hiawatha Avenue. Its other boundaries are Hiawatha Avenue to the east, East Lake Street to the south, and Bloomington Avenue to the west. The Phillips community has only been subdivided into smaller neighborhoods within the last couple years; the boundaries of East Phillips were officially designated on December 23, 2005. As this change has been fairly recent, most residents still refer to the area as just "Phillips". The neighborhood also features the Little Earth residential community.

Midtown Phillips is a neighborhood within the Phillips community in Minneapolis. Its boundaries are East 24th Street to the north, Bloomington Avenue to the east, East Lake Street to the south, and Chicago Avenue to the west. The community is primarily residential by land use and is home to over 4,700 residents from diverse backgrounds according to the 2010 Census. Prominent employers include the Children's Hospital of Minnesota Minneapolis location, Abbot Northwestern Hospital, and Allina Healthcare Services. There are approximately 11,800 people who work in Midtown Phillips according to the 2010 Census. Cultural institutions include the Midtown Global Market, Saint Paul's Church, Abubakar As-Sadique Islamic Center, and the Heart of the Beast Theater. The $189 million redevelopment of the vacant Sears building at Chicago Avenue and Lake Street into a mixed-used development of offices, hotel, retail and housing located in Midtown Phillips is one of the most important projects undertaken in Minneapolis in recent times. Stewart Park and Andersen United School are located in the core of Midtown Phillips. According to niche.com, Andersen School has 1,086 students in grades PK and K-8. According to state standards, 28% of students at this school are considered proficient in math and/or reading. According to the McKnight Foundation website, Andersen United School has a student body which is 95% low income, and/or students of color, and/or bilingual. Health institutions in Midtown Phillips include Abbott Northwestern Hospital, Children's Hospital of Minnesota, Allina Health, and numerous private practices. Chicago Avenue, which borders the west end of Midtown Phillips, was proclaimed a wellness corridor by the Minneapolis adapted corridor plan titled the Chicago Avenue Corridor Plan. http://www.ci.minneapolis.mn.us/cped/planning/cped_cacp

The Penny George Institute for Health and Healing is an integrative medicine institute in Minneapolis, United States.

Powderhorn Lake is a small, natural lake within Powderhorn Park in Minneapolis, Minnesota, United States. The lake has a shoreline of 0.62 miles (1.00 km), a surface area of about 11 acres (0.045 km2), and a maximum depth of 24 feet (7.3 m). The lake is popular local destination for fishing and it is serves as a backdrop for many events and activities in Powderhorn Park. The lake takes its name from its original shape that more closely resembled a powder horn.

Abbott Northwestern Hospital is a 686-staffed bed teaching and specialty hospital based in Minneapolis, Minnesota. It is a part of the Allina Health network of hospitals and clinics.

Phillips Eye Institute consists of two specialty eye hospitals in Minnesota, United States. Phillips Eye Institute's location, in Minneapolis, Minnesota opened in 1987. Phillip's newest location, in Buffalo, Minnesota opened in 2008. Phillips Eye Institute specializes in the diagnosis, treatment and care of eye disorders and diseases. Phillips Eye Institute is part of the Allina Health System.On March 1, 2022 the institute vacated their main building, moving operations to the nearby Abbott-Northwestern Hospital building.

The Powderhorn Park neighborhood of Minneapolis, Minnesota, United States (part of the larger Powderhorn community) is located approximately three miles south of downtown and is bordered by East Lake Street to the north, Cedar Avenue to the east, East 38th Street to the south, and Chicago Avenue to the west. Its namesake is the city's Powderhorn Park facility in the northwestern part of the neighborhood around Powderhorn Lake, which contains playing fields, playgrounds and a park building that hosts community education classes ranging from pottery to yoga. In winter, the Minneapolis Park and Recreation Board sets up a portable warming house and the lake is used for ice skating.

Phillips is a community in Minneapolis, just south of downtown. Phillips is a diverse area in many ways: its population includes people of many nationalities; it has a mix of residential, commercial and industrial uses; and it is home to several large employers such as Abbott Northwestern Hospital, Wells Fargo Mortgage and Allina Health Care Services along with small neighborhood businesses. Traditionally, it was both a community and a neighborhood (in Minneapolis, a neighborhood is a subdivision of a community). On May 9, 2002, Phillips neighborhood was subdivided into four smaller neighborhoods. The official neighborhoods are now known as Ventura Village, Phillips West, East Phillips, and Midtown Phillips. Though not an officially designated neighborhood, Phillips also includes the Little Earth residential area. The boundaries of the Phillips community are Interstate 94 to the north, Hiawatha Avenue to the east, Lake Street to the south, and Interstate 35W to the west. The neighborhood was named after Wendell Phillips, a 19th century abolitionist. It was in this neighborhood that the American Indian Movement was founded in 1968.The $189 million redevelopment of the vacant Sears building at Chicago Avenue and Lake Street into a mixed-use development of offices, hotel, retail and housing located in Midtown Phillips is one of the most important projects undertaken in the city in recent times. At the east side of the community, along the Hiawatha Avenue transit corridor, the Little Earth Trail connects many smaller neighborhoods, parks, businesses, and multi-use trails.