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The Missouri Botanical Garden is a botanical garden located at 4344 Shaw Boulevard in St. Louis, Missouri. It is also known informally as Shaw's Garden for founder and philanthropist Henry Shaw. Its herbarium, with more than 6.6 million specimens, is the second largest in North America, behind that of the New York Botanical Garden. The Index Herbariorum code assigned to the herbarium is MO and it is used when citing housed specimens.

Festival of Nations is a free, multicultural public event, held yearly, organized by the International Institute of St. Louis in Tower Grove Park, a city park on Grand Boulevard, featuring food booths of many ethnic cuisines, dance, music, arts, crafts and an international bazaar.

The Climatron is a greenhouse enclosed in a geodesic dome that is part of the Missouri Botanical Garden in St. Louis. Initiated by then Garden director Frits W. Went, the dome is the world's first completely air-conditioned greenhouse and the first geodesic dome to be enclosed in rigid Plexiglass (Perspex) panels. Completed in 1960, it was designed by T. C. Howard, of Synergetics, Inc., Raleigh, North Carolina. The broad climatic range within the dome, which recreates a lowland rain forest, is achieved by sophisticated climate controls without using interior partitions.The structure is an unpartitioned half-sphere dome, 42 m in diameter and 21 m high. The frame is supported by aluminum tubes under compression and aluminum rods under tension. The St. Louis architects Murphy and Mackey were the architects on record. Synergetics, Inc were the designers of the dome. The architects received the 1961 R. S. Reynolds Memorial Award of $25,000 for their architectural use of aluminum. In 1976 it was named one of the 100 most significant architectural achievements in United States history.The dome contains a small stone pre-existing neo-classical pavilion and over 400 varieties of plant life. A bank of 24 flood lights, revolving at night in five-minute cycles, simulates noon light on one side of the dome and moonlight on other side. The climate ranges from the Amazon through Hawaii and Java to India. Over time, the building experienced deterioration of the original Plexiglas panels and the adverse effect of humidity on some metal elements. The greenhouse was closed for extensive renovations in 1988 and reopened in March 1990. The original Plexiglas glazing was replaced with 2,425 panes of heat-strengthened glass (containing a plastic interlayer called Saflex) and coated with a low-emissivity film. In 2010, the Botanical Garden celebrated the 50th anniversary of the Climatron.

Tower Grove Christian Academy is a PreK-12 Coed Private Christian School located in Saint Louis, Missouri. It is directly adjacent to Tower Grove Park.

Tower Grove Park is a municipal park in St. Louis, Missouri. Located on the south side of the city, the elongated 289-acre (117 ha) park extends 1.6 miles (2.6 km) from Kingshighway Boulevard east to Grand Boulevard. The park’s predominately residential surroundings include the neighborhoods of Southwest Garden, Shaw, Tower Grove East, and Tower Grove South. Both Tower Grove Park and the neighboring Missouri Botanical Garden were part of the estate of 19th-century businessman and botanist Henry Shaw. In 1868, Shaw donated the land for the park to the city of St. Louis.

On October 24, 2022, a mass shooting occurred at Central Visual and Performing Arts High School in the Southwest Garden section of St. Louis, Missouri, United States when a 19-year-old former student open fired on students and staff killing two and injuring seven before being fatally shot by police.

Central Visual and Performing Arts High School (formerly Central High School) is a magnet high school in St. Louis, Missouri, part of the St. Louis Public Schools. Founded in 1853, Central High School is the oldest public high school west of the Mississippi River, although it has moved several times and merged with a magnet school in 1984. Central VPA specializes in the arts, with students taking courses in three art majors, including visual art, musical art, and performing art, with focuses on ceramics, drawing and painting, photography, instrumental music, vocal music, dance, and theater.

Cleveland Junior Naval Academy (also known as Cleveland High School) was a magnet military academy high school in St. Louis, Missouri and was a part of the St. Louis Public Schools. Cleveland High School opened in 1915 as a comprehensive high school, merging with the Junior Naval Academy in 1984. The Junior Naval Academy was a magnet military academy, founded in 1981. In 2006, the school moved from its original location on Louisiana Avenue (38.5777°N 90.2429°W / 38.5777; -90.2429) to the Pruitt Military Academy building on North 22nd Street, then, in 2010, it moved from Pruitt to the Southwest High School building at Arsenal and Kingshighway. In 2021, the St. Louis Public Schools board voted to close the location effective the upcoming school year.

Southwest Garden is a neighborhood of St. Louis, Missouri, located south of The Hill and Forest Park Southeast, west of the Missouri Botanical Garden and Tower Grove Park, east of Lindenwood Park and Clifton Heights, and north of North Hampton. Bisected by Kingshighway Boulevard, one of St. Louis’s major arterial roads, Southwest Garden is named for its proximity to the Botanical Garden. The neighborhood is notable for its architectural heritage, containing two National Historic Landmark Districts: Shaw’s Garden, containing the portion of the neighborhood between Kingshighway and the Botanical Garden, covers a tract of land formerly owned by Garden founder Henry Shaw. This area is notable for its highly intact collection of multifamily residential buildings (primarily duplexes and fourplexes) dating to the late 19th and early 20th centuries. Reber Place, located directly west of Tower Grove Park, which contains a diverse mix of frame homes, multifamily buildings, and bungalows dating to the late 19th and early 20th centuries.In addition to the Botanical Garden and Tower Grove Park, other notable locations within the neighborhood include: The St. Louis Psychiatric Rehabilitation Center, a 196-bed psychiatric hospital operated by the Missouri Department of Mental Health on a 32-acre (13 ha) campus on Arsenal Street in the southern portion of the neighborhood. The campus includes the former St. Louis County Lunatic Asylum, designed by architect William Rubold and completed in 1869. The Romanesque Revival building is adorned with a prominent 200-foot (61 m) tall cast iron dome. Situated on the highest point in the city, the structure can be seen from up to 30 miles (48 km) away. Sublette Park, a neighborhood park including a playground, a pavilion built by the Boy Scouts of America, tennis courts and a soccer field.The neighborhood is covered by St. Louis Board of Aldermen wards 8, 10 and 24.

Gateway STEM High School (formerly known as Gateway Institute of Technology) is a public magnet high school in St. Louis, Missouri, United States.

Sado is a restaurant in St. Louis, Missouri. It was a semifinalist in the Best New Restaurant category of the James Beard Foundation Awards in 2024.

Shaw is a neighborhood in St. Louis, Missouri. It is bordered on the North by Interstate 44, the east by S. Grand Blvd, the west by Tower Grove Ave and the Missouri Botanical Gardens, and the south by Tower Grove Park. The Shaw Neighborhood is a local historic district whose historic structure and character is protected by ordinance. A mix of single family homes and multifamily buildings create a diverse population of different ages and backgrounds.