Alma School/Main Street station

The East Valley Institute of Technology (EVIT) is a public school district serving the eastern portion of the Phoenix, Arizona metro area. It is a joint technological education district with programs are available to students at the member high schools. EVIT serves 10th, 11th, and 12th grade students from the sending districts that meet class prerequisites.

Westwood High School is a 4-year public high school in the western part of Mesa, Arizona, United States under the jurisdiction of Mesa Public Schools. It was opened in 1962 with Elias Brimhall as the founding principal. In the 1983–84 school year, it was honored as a Blue Ribbon school. In 2018 it was reclassified as a "A" school through the Arizona Department of Education school accountability system.It is the zoned public high school of the Salt River Pima–Maricopa Indian Community.

Sycamore/Main Street, also known as The Asian District, is a station on the Valley Metro Rail line in Mesa, Arizona, United States. The station is located one block east of the intersection of Dobson Road and Main Street, in front of the former Tri City Mall. It was the original eastern terminus for Valley Metro Rail when the line opened in 2008. Adjacent to Mekong Plaza and other East Asian businesses, it serves as an access point to Mesa's Asian district. A large park and ride lot is located adjacent to the station's bus terminal on the north side of Main Street.

Country Club/Main St is a station on the Metro light rail line in Mesa, Arizona, United States. The station is located one block east of the intersection of West Main Street and South Country Club Drive and opened on August 22, 2015.

Tri-City Pavilions, formerly Tri-City Mall, is a shopping mall in Mesa, Arizona, United States. It was developed in 1968 as an enclosed shopping mall featuring Diamond's and JCPenney as the anchor stores. The mall underwent a period of decline following the opening of Fiesta Mall in 1979, particularly after Diamond's consolidated with its store in that mall in 1984. Despite a mall-wide renovation completed in 1985 and the addition of new tenants such as ZCMI and Bealls, Tri-City Mall continued to diminish throughout the 1990s, with JCPenney closing in 1998. The mall was demolished in 1999 in favor of a strip mall anchored by Safeway Inc., although the former JCPenney building remained until 2006. Tri-City Pavilions is owned and managed by Lamar Companies.

Wilkes University, Mesa, is a private university located in Mesa, Arizona. It began offering classes in Arizona in 2013. The university was established to provide first-generation college students access to higher education. It was one of four colleges invited to participate in Mesa's H.E.A.T. (Healthcare, Education, Aerospace, Technology/Tourism) Initiative for Economic Development.In 1933, the Wilkes University main campus was founded in Wilkes-Barre, Pennsylvania. The university signed an agreement with Mesa, Arizona to bring a satellite location to the city in July 2012. Under the agreement, Mesa negotiated a five-year lease for Wilkes University in the Mesa Center for Higher Education.Wilkes University, Mesa began offering classes in 2013. It was the fourth university to open a campus in Mesa that year. In 2013, the university began offering a MBA program. The main campus was ranked 74th best regional university in the northern United States by U.S. News & World Report the following year. In November 2014, Wilkes University, Mesa offered over $150,000 in scholarships to Mesa residents. The university focuses on providing education opportunities to first-generation students.The university hosted a writer's conference and All-Collegiate poetry slam in December 2014. In January 2015, Wilkes University, Mesa began offering business majors including accounting, entrepreneurship, finance, management, marketing and sports and event management. Additionally, the university added master's degrees in creative writing and education to its degree plans as well as a doctor of education program in educational leadership. Wilkes University, Mesa graduated its first class of MBA students in December 2014.

The i.d.e.a. Museum (formerly the Arizona Museum for Youth) is a museum designed for exhibiting, teaching, and interacting with the fine arts. It changed its name on February 6, 2014, to i.d.e.a., which stands for "imagination, design, experience, art." The i.d.e.a. Museum is primarily designed for younger age groups but has exhibits, classes and activities designed for all age groups. The museum hosts several changing exhibitions each year and features ArtVille, an art-town for kids ages 0 – 4. As part of the exhibits, art classes, workshops and family programs are available to teach art principles and techniques. The i.d.e.a. Museum is run and operated by the City of Mesa, Arizona and is located at 150 Pepper Place in downtown Mesa.

The Woman's Club of Mesa was a women's club in Mesa, Arizona. Their former clubhouse building is listed on the National Register of Historic Places and is now the Guild of the Vale.

Mesa Grande Cultural Park, in Mesa, Arizona, preserves a group of Hohokam structures constructed during the Classic Period. The ruins were occupied between AD 1100 and 1400 (Pueblo II – Pueblo IV Era) and were a product of the Hohokam civilization that inhabited the Salt River Valley. There the Hohokam constructed an extensive system of water canals. It is one of only two Hohokam mounds remaining in the metro Phoenix area, with the other being the Pueblo Grande Museum Archaeological Park. The site's central feature is a massive ruin of adobe walls and platforms.It was listed on the National Register of Historic Places in 1978 when it was owned by B-movie actress Acquanetta and her husband Jack Ross. The site was acquired from them in 1988 by the city of Mesa.Since the 2013 completion of the Mesa Grande Visitor's Center, the site is seasonally open to the public from October through May.The Mesa Grande Cultural Park is operated by the Arizona Museum of Natural History, which is undertaking archaeological studies there. The mound remains remarkably intact. The general site remains protected but undeveloped. The ruins are located to the west and across the street from the former Mesa Lutheran Hospital, which became a Banner Health corporate center housing billing and information technology employees. Artifacts presumably associated with the ruins have been found in the neighborhood to the west. Axe heads, arrow heads, and pottery sherds were regularly uncovered and collected by residents during the 1960s and 1970s just under the surface of the earth in private property there.

The Arizona Museum of Natural History (originally the Mesa Southwest Museum) located in Mesa, Arizona, is the only natural history museum in the greater Phoenix area. It exhibits the natural and cultural history of the Southwestern United States.

Mesa Riverview is an outdoor shopping center in Mesa, Arizona (part of the Phoenix metropolitan area) located in the northwestern corner of the city near Loop 202 and Dobson Road. The shopping center has a gross leasable area of 1,115,112 square feet (103,000 m2). Anchor stores include Bass Pro Shops, Cinemark Theatre, Home Depot, Bed Bath and Beyond, Petco, Walmart, Marshalls, Office Max, and Jo-Ann Fabrics.The shopping center is currently owned by Kimco Realty Corp.

The West Second Street Historic District is the oldest historic district in the city of Mesa, Arizona. It was added to the National Register of Historic Places in 1999 and features a greater variety of architectural styles than other historic districts in the city. Styles represented include Colonial Revival, Spanish Colonial Revival, Tudor Revival, Mission Revival, and Pueblo Revival. The district includes many homes of Mesa's most prominent families from its early history.The original boundaries of the district were roughly between Robson St. and Center St., from 1st St. to 3rd St. In 2003, the district was expanded to include the entire area roughly bounded by Robson St., University Dr. and MacDonald St.An annual historic home tour, sponsored by the Mesa Historical Museum, allows the public to visit several homes in the district.