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Pioneer Street is the continuation of Boni Avenue east of Epifanio de los Santos Avenue (EDSA) in eastern Metro Manila, Philippines. The street has four lanes for most of its course beginning at the EDSA junction in Barangka Ilaya, Mandaluyong, where traffic emerges from the Boni Avenue tunnel, up to its easternmost point at the Shaw Boulevard junction at the boundary of barangays Kapitolyo and San Antonio in Pasig, adjacent to Ortigas Center. En route, it passes through the Robinsons Cybergate Complex where Forum Robinsons mall is located; the United Laboratories plant; and Greenfield District, a mixed-use development south of Ortigas Center by the junction with Shaw Boulevard. Pioneer Street is also the location of several new condominium developments, call center sites and a few strip malls. It is served by Boni Station of the MRT-3 at EDSA.

Greenfield District is a transit-oriented mixed-use development next to a rail station in Mandaluyong, Metro Manila, the Philippines. It is a redevelopment of the old United Laboratories (Unilab) pharmaceutical plant and adjacent retail market in the village of Highway Hills adjoining the Kapitolyo village of Pasig to the east. The 15-hectare (37-acre) mixed commercial and residential complex is in the crossroads of EDSA and Shaw Boulevard immediately south of the Ortigas Center financial district. It consists of an office tower, condominium high-rises, a central park, retail centers and recreational facilities.

The One San Miguel Avenue is an office skyscraper located at San Miguel Avenue (hence the building's name) in Ortigas Center, Pasig, Philippines. It was completed in 2001 and stands at 183 metres (600.39 feet) from ground up to the architectural top, although if measured with its antennas, it stands at 203 metres (666 feet). It has 54 floors aboveground and 7 basement levels.

Boni station (also called Boni Avenue station) is a Manila Metro Rail Transit (MRT) station situated on Line 3. It is the eighth station for trains headed to Taft Avenue and the sixth station for trains headed to North Avenue. It is located in Mandaluyong and is named so due to its proximity to Boni Avenue, which is in turn named after the nickname of Bonifacio Javier, a World War II guerilla leader and former mayor of Mandaluyong. It has several restaurants and shops that surround the station, including a public market located across the train station.

Forum Robinsons, formerly called as Robinsons Place Pioneer, was a shopping mall located in Mandaluyong, Metro Manila, Philippines owned and operated by Robinsons Land. The mall opened on November 17, 2004. It is the 18th mall opened by Robinsons and the first mall in Mandaluyong with a gross floor area of 56,000 square meters (600,000 sq ft). The former name Robinsons Place Pioneer was dubbed after its location, Pioneer Street. Back then, the mall was envisioned to become a one stop shop for everyone in Cybergate Complex which was in turn envisioned to become a cyberhub in the city. In 2010, the mall was renamed to its current name to re-position itself as a cyber lifestyle mall focusing on IT products and to align itself with the vision of the Cybergate Complex. The mall closed on April 30, 2022 to give way for its redevelopment works, which was originally set to start on early 2020 but was delayed due to the COVID-19 pandemic in the Philippines. The new complex will feature office towers atop the new mall area.

Robinsons Cybergate, also known as Robinsons Cybergate Complex and Cybergate City, is a mixed-use development located along EDSA corner Pioneer Street in Mandaluyong, Metro Manila, Philippines. Owned by Robinsons Land Corporation, the development is anchored by four office buildings named Robinsons Cybergate Center Towers 1, 2, 3 and Robinsons Cybergate Plaza which has a Go Hotel.The site is an economic zone, as declared by the Philippine Economic Zone Authority (PEZA). It sits on a 6-hectare site in close proximity to public transportation along EDSA and the Boni station of the MRT Line 3. The development is also home to the Office of the Vice President of the Philippines (OVP). The OVP moved to Cybergate Plaza in 2022, under the tenure of Sara Duterte.There is also a Robinsons Cybergate in Cebu which started development in 2010. It is located in near Chung Hua in Osmeña Boulevard, Cebu City.

The Santa Monica–Lawton Bridge, also known as the Kalayaan Bridge and Bonifacio Global City–Ortigas Link Bridge, is a four-lane, two-way bridge across the Pasig River that connects Lawton Avenue in Makati to Fairlane Street (near Santa Monica Street to where the bridge is also named after) in Kapitolyo, Pasig. The bridge spans 613.77 meters (2,013.7 ft) and the construction cost of the bridge is ₱1.857 billion as of 2017. The bridge also includes a 565-meter (1,854 ft) viaduct that connects it to 8th Avenue in Bonifacio Global City, Taguig. The bridge aims to decongest nearby thoroughfares like EDSA and Circumferential Road 5 and cut travel time between Taguig and Ortigas from 30 minutes or 1 hour to only 12 minutes. The bridge was partially opened on June 12, 2021, with the completion of its key component, the Kalayaan Bridge, while the Lawton Avenue – Global City Viaduct opened on October 1, signaling the full completion of the bridge.The bridge is currently passable to light vehicles only. The Kalayaan Bridge does not have facilities or infrastructure for pedestrians.

The St. Francis Shangri-La Place, also known as The St. Francis Towers 1 & 2 are twin-tower residential condominium skyscrapers in Mandaluyong, Philippines. The towers are the 6th and 7th-tallest buildings in the country and Metro Manila as well, and are currently the second tallest twin towers in the Philippines surpassing Pacific Plaza Towers with a height of 212.88 metres from the ground to its architectural spire. It also has two of the most floors in the Philippines. The buildings have 60 floors above ground, including a podium which connects the two towers, and 5 basement levels for parking, and are considered one of the most prestigious residential buildings in the Philippines.

Astoria Hotels and Resorts is a Philippine hospitality chain established in 2001.

Philippine Charity Sweepstakes Office board secretary Wesley Barayuga was killed by an unidentified gunman on July 30, 2020 in Mandaluyong, Metro Manila, Philippines. Barayuga was initially speculated to have been killed due to work-related issues. He was also without evidence, accused of being part of a 'narcolist' created for President Rodrigo Duterte's Philippine drug war. Despite Barayuga's profile as a high-ranking government official and a former police officer, his killing remained a cold case for four years until police officer Santie Mendoza implicated National Police Commission commissioner Edilberto Leonardo and then PCSO general manager Royina Garma of masterminding the killings during a House of Representatives inquiry in September 2024, two years into the presidency of Duterte's successor Bongbong Marcos.

Shangri-La Plaza is a shopping mall located in Ortigas Center, Mandaluyong, Philippines. It is owned and operated by the Kuok Group of Companies, the owner of the worldwide chain of Shangri-La Hotels and Resorts. Shangri-La Plaza opened on November 21, 1991 and contains more than 300 shops and restaurants.

Shaw Boulevard station (also called Shaw for short) is an elevated Manila Metro Rail Transit (MRT) station situated on Line 3. The station is located in the Mandaluyong portion of Ortigas Center and is named after Shaw Boulevard, since the station lies directly above the boulevard. The station is the seventh station for trains headed to Taft Avenue and North Avenue. Shaw Boulevard station lies at the center of the whole line, with many commuters regarding it as the "central terminal" of the line.