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The Burnstein-Malin Grocery, also known as the Malin's Kosher Delicatessen, Pickle Barrel Delicatessen, and The Pickle Barrel, was a historic building located in Des Moines, Iowa, United States. This commercial building was constructed in two parts. The first part was a 2½-story frame house built back from Sixth Avenue for Frank W. Whitcomb in 1896. It was converted into Burnstein Grocery in 1923. The number of commercial establishments along this street increased five-fold between 1920 and 1937, and the Whitcomb house exemplified this transition. The single-story brick section on the front was completed in 1940. The two sections shared a common wall. This was one of several modified residence-specialty stores that were located along Sixth Avenue from the 1930s through the 1950s, but by the end of the century it was only one of two that remained standing. The building was listed on the National Register of Historic Places in 1998. It has subsequently been torn down and it was delisted from the National Register in 2019.

The New Lawn is a historic building located in Des Moines, Iowa, United States. This three-story, brick structure was completed in 1915. It features seven units, an U-shaped plan, a symmetrical facade with projecting wings, polychrome brick veneer, a series of quadruple ribbon windows, and a flat roof. The building is located on Sixth Avenue, which by the turn of the 20th century had become a major route utilized by vehicular traffic and streetcar lines. Its proximity to this transportation corridor illustrates the emergence of higher and denser residential use in this area of Des Moines. The apartment building was listed on the National Register of Historic Places in 1996.

The F.E. Haley Double House, also known as the Gordon Apartments, is a historic building located in Des Moines, Iowa, United States. This double house is significant as being one of the first of this kind of building type built in the Des Moines area. The double house was developed in this area starting in the Victorian era. This 2½-story, brick Colonial Revival was built in 1897 by Felix E. Haley. He managed the building, but never lived here, suggesting he had it built for rental/investment purposes. The building features a symmetrical facade, brick in several colors and textures, and a sloping flat roof. While it originally had a full-length front porch, this one is not the original. The four lunette-shaped windows in the frieze feature shield-shaped panes. The house was listed on the National Register of Historic Places in 1998.

The William W. and Elizabeth J. Ainsworth House, also known as the Catholic Worker House and the Dingman House, is an historic building located in Des Moines, Iowa, United States. Ainsworth was a Des Moines businessman who was engaged in various professional occupations. His wife Elizabeth took title to this property in 1886, and they built this 21⁄2-story, frame, Queen Anne house in what was then the suburban community of North Des Moines. It features a hip roof, intersecting gables, a front porch, an enclosed porch in the back, and 2-story bay windows on the south and east elevations. Built as a single-family dwelling, it is now a half-way house for social services operated by the Catholic Worker Movement. The house calls attention to the increased importance of North Des Moines as a residential neighborhood for business and professional people in the late 19th-century Des Moines area. It was listed on the National Register of Historic Places in 1998.

Fire Station No. 4 is a historic building located in Des Moines, Iowa, United States. This is one of a small group of fire stations built in the city around the turn of the 20th-century, and one of the earliest local examples of this building type. It was completed about 1896, and it has an addition on the east side that was built in 1962. The two-story brick structure features a tiled hip roof, stone beltcoursing, a projecting bay window on the main facade on second floor, and a Gibbs surround with stone voussoirs that surround the main entrance. The building was listed on the National Register of Historic Places in 1979.

Franklin Apartments, also known as the Rood House, Antes House, and the Coffin Apartments, is a historic building located in Des Moines, Iowa, United States. The building was constructed as a single-family dwelling for the Rood family in 1896. It was converted into a seven unit apartment building in 1914, and then substantially remodeled four years later by Frank B. Coffin into a three unit apartment building. The building is located on Sixth Avenue, which by the turn of the 20th century had become a major route utilized by vehicular traffic and streetcar lines. Its proximity to this transportation corridor illustrates the emergence of higher and denser residential use in this area of Des Moines. The apartment building was listed on the National Register of Historic Places in 1996.

The Des Moines Grand Prix was a temporary street circuit located in Des Moines, Iowa, which hosted a round of the SCCA Trans-Am Series four times between 1988 and 1992.

Mercy College of Health Sciences is a private Roman Catholic college focused on healthcare and located in Des Moines, Iowa. Established by the Sisters of Mercy in 1899, Mercy College bachelor's degrees, associate degrees, and certificate programs in the health sciences.

The Charles H. and Lena May Weitz House is a historic building located in Des Moines, Iowa, United States. This 1½-story frame dwelling features a gable-front-and-wing configuration, a front porch located in the el of the facade, a single-story bay window on the south elevation, a dormer window on the facade, and steeply pitched roofs. Behind the house is a two-story, brick outbuilding. It is one of the few brick out buildings in the neighborhood. Both were constructed about 1891 by Charles H. Weitz for his home and his workshop. He was a partner and elder son of the founder of Charles Weitz & Sons, which was a prominent Des Moines construction firm in the late 19th and early 20th-century. During his time with the company, Charles H. Weitz "introduced modern methods of construction to this family business, thereby assuring its potential for growth." The Weitz Company grew to become a nationally recognized full-service general contractor. The house and outbuilding were listed together on the National Register of Historic Places in 1998.

The Bates Park Historic District is located on the north side Des Moines, Iowa, United States. It has been listed on the National Register of Historic Places since 1996. It is part of the Towards a Greater Des Moines MPS.

Lauridsen Skatepark, at 88,000 square feet, is currently (as of July 2021) the largest public skatepark in the United States. Opening on 7 May 2021, it was designed by project engineer and landscape architect Tim West, alongside Shane Tully of Snyder & Associates with support from California Skateparks, Landscape Architects and Structural Engineers, Polk County Public Works and the City of Des Moines and is located along the west bank the Des Moines River, at 901 2nd Avenue in downtown Des Moines, Iowa, which is on riverfront property near Second Avenue and School Street just northeast of Wells Fargo Arena. The Lauridsen Skatepark held the only Olympic skateboarding qualifying event in North America sanctioned by World Skate for the 2021 Olympics in Tokyo. The park has been used for competitions and exhibitions. Citizens have painted several murals on it since it opened. In May 2023, vandals caused thousands of dollars worth of property damage to the park's bathrooms. This prompted the facilities to close earlier. Additionally in 2023 it was proposed a neighboring dog park be converted into a much-needed parking lot.

The Sixth and Forest Historic District is located in Des Moines, Iowa, United States. It is a Victorian era suburban commercial district on the northeastern and northwestern corners of the junction of 6th and Forest Avenues, and originally contained six buildings. The buildings on the northeast corner have subsequently been torn down. The historic district has been listed on the National Register of Historic Places since 1996. It is a part of the Towards a Greater Des Moines MPS.