Old Main, Goethean Hall, and Diagnothian Hall

Franklin & Marshall College (F&M) is a private liberal arts college in Lancaster, Pennsylvania. Founded in 1853 on the merger of Franklin College and Marshall College, F&M is named for Benjamin Franklin, who gave the college its first endowment, and John Marshall. Founded in Lancaster, Pennsylvania, F&M's early years were bilingual between German and English, serving the local Pennsylvania Dutch community. Originally founded as the German College and Charity School, Franklin College received its charter in 1787 from the Pennsylvania General Assembly as a German-language alternative to the University of Pennsylvania. Among its early supporters were Benjamin Franklin, Robert Morris, and Peter Muhlenberg.Franklin & Marshall was the first coeducational college in America, serving both men and women in an experimental curriculum. Among its first students was Richea Gratz, the first Jewish female college student in the United States. The college offers various majors and minors across 62 fields of study, including the humanities, social sciences, natural sciences, and other disciplines. The college operates an advanced studies program in Bath, England. All students are undergraduates, and nearly all live on campus. F&M is the 7th highest baccalaureate producer of Fulbright scholars.

Lancaster Theological Seminary is a seminary of the United Church of Christ in Lancaster, Pennsylvania. It was founded in 1825 by members of the German Reformed Church in the United States to provide theological education for prospective clergy and other church leaders.

Daniel Scholl Observatory was the astronomical observatory built by Franklin and Marshall College in Lancaster, Pennsylvania. Construction began in 1884 and the building was dedicated June 16, 1886. Total cost of the observatory and equipment was $13,579. The Observatory was named after Mr. Daniel Scholl of Maryland because his child donated the money for its establishment. Building cost- $3,000 Steel Dome $2,000 by Grubb & Sons, Dublin, Ireland Equipment cost-$8,579 total $4,199 for 11" Repsold Telescope (Hamburg, Germany) $2,200 lens manufactured by Alvan Clark & Sons, Cambridge, Massachusetts $2,180 for chronometer, chronograph, transit, clock and other equipmentStarting in 1889 it was one of the official Pennsylvania weather stations. In 1925 the observatory was moved 200 yards north to make way for a dormitory. The observatory was razed in 1966.

The North Charlotte Street Historic District is an historic, American, tobacco warehouse complex and national historic district that is located in Lancaster, Lancaster County, Pennsylvania. It was listed on the National Register of Historic Places in 1989.

The Unitarian Universalist Church of Lancaster is a Unitarian Universalist church located at 538 West Chestnut Street, Lancaster, Pennsylvania. The church building is part of the Historic District of the City of Lancaster. The congregation is a member of the Unitarian Universalist Association, in the Association's Central East Region (Joseph Priestley District). Like all Unitarian Universalist churches, it is noncreedal, covenantal and religiously liberal. According to the UUA, the Lancaster church currently has 275 members and is an LGBTQIAA+ Welcoming Congregation.

The Hamilton Watch Complex is a former industrial complex in Lancaster, Pennsylvania. It was owned by the Hamilton Watch Company and was used as their headquarters from the company's founding in 1892, until 1980. The complex was listed on the National Register of Historic Places in 1982. The main building was converted into a luxury apartment and condominium complex, while the Administrative Offices are now home to a Montessori school called "New School Montessori."

Jacob L. Frey Tobacco Warehouse is a historic tobacco warehouse located at Lancaster, Lancaster County, Pennsylvania. It was built about 1870, and is a two-story, irregular brick building with a raised basement and gable front roof. It is three bays wide and approximately 60 feet deep.It was listed on the National Register of Historic Places in 1990.

The J. B. Milleysack Cigar Factory is an historic American cigar factory which is located in Lancaster, Lancaster County, Pennsylvania. It was listed on the National Register of Historic Places in 1990.

The Slater Cigar Company is an historic site in the United States that encompasses two cigar factory and tobacco warehouse buildings. Located in Lancaster, Lancaster County, Pennsylvania, it was listed on the National Register of Historic Places in 1990.

The Harrisburg Avenue Tobacco Historic District is an historic tobacco warehouse complex and national historic district which is located in Lancaster, Lancaster County, Pennsylvania. It was listed on the National Register of Historic Places in 1990.

West Lawn, also known as the Embassy House Apartments, is a historic home located at Lancaster, Lancaster County, Pennsylvania. It was built in 1873–1874, and is a T-shaped dwelling with a 2+1⁄2-story main section and 2+1⁄2-story rear wing with a slate covered mansard roof in a combined Italianate / Second Empire style. It features a 3+1⁄2-story tower with a mansard roof. It once housed a fraternity and in 1973 was converted to apartments.It was listed on the National Register of Historic Places in 1984.

The Northwest Corridor is a neighborhood on the northwestern corner of Lancaster, Pennsylvania. With an overall distance of 1.5 miles (2.4 km), this planned corridor links key socioeconomic, commercial, industrial, and civic developments within the city and in the nearby suburbs of East Hempfield Township and Manheim Township.