Old Downtown Harrisburg Commercial Historic District

Keystone Building is a historic commercial building located at Harrisburg, Dauphin County, Pennsylvania. It was built in 1875 as the State Printing Office. It is a six-story office building, plus basement, 7 bays wide and 12 bays deep. It is faced in granite on the first floor, with brick above. It was remodeled in 1917, with the addition of a structural steel frame and 12-inch reinforced floors.It was added to the National Register of Historic Places in 1979.This building is not to be confused with the Commonwealth Keystone Building, a nearby State Government office building completed in 2000.

SoMa, or South of Market Street, is a neighborhood in Downtown Harrisburg, Pennsylvania around South Third Street, bounded by Market to the north, 3rd to the west, Chestnut to the south, and 4th to the east. The name "SoMa" derives from the area being "South of Market Street", coined by Harristown Enterprises in 2007 to rebrand the South Third Street area for new development relating to international business and the arts. Eight restored historic buildings became 20 apartments branded as "SoMa on Third". The area is a popular housing area for students attending the nearby Harrisburg University. The area contains popular retail and bar & restaurant destinations and hosts frequent block parties in which they participate with other incoming vendors and entertainment.

Whitaker Center for Science and the Arts is located in Harrisburg, Pennsylvania. The center is the first complex of its kind in the United States to use science as an entry to the arts. Whitaker Center exhibits science, the performing arts, and a digital cinema under one roof. The center encompasses a total of 130,000 square feet (12,000 m2), including the three main components, plus STAGE TWO, Discovery Lab classrooms, multi-purpose rooms, the AMP Grand Lobby and the Kunkel Gallery.

Salem United Church of Christ, formerly known as Old Salem Reformed Church, is a historic Reformed church at 231 Chestnut Street in Harrisburg, Dauphin County, Pennsylvania. The church was built in 1821–1822, and is a two-story brick building in a Classical style. It features a large square bell tower topped by a domed cupola. The tower is flanked by two, three-story towers with stepped gables. A two-story, Sunday school annex was built to the rear of the church in 1862.It was added to the National Register of Historic Places in 1975.

Camp Curtin Memorial Methodist Episcopal Church, also known as Curtin Heights Church and Camp Curtin Memorial-Mitchell United Methodist Church, is a historic Methodist Episcopal church located in Harrisburg, Dauphin County, Pennsylvania.It was added to the National Register of Historic Places in 2010. The Susquehanna Conference of the United Methodist Church announced plans, in December 2018, to consolidate or sell roughly 10 churches in the greater Harrisburg area. In February 2021, newspapers reported that Camp Curtin Memorial-Mitchell United Methodist Church would be sold "to a church off of the west coast that is buying it as a church for veterans," and that "a veterans' ministry" would be established at the historic church; however, the realtor involved in the transaction reported a month later that the church was "back on the market" because the deal had fallen through. News accounts at the time noted that the realtor's most recent listing stated that the "15,852-square-foot property [was] listed for $155K," and that the church was] zoned 'commercial neighborhood,' which provides the possibility of a number of uses for the property."

William Seel Building is a historic commercial building located at Harrisburg, Dauphin County, Pennsylvania. It was built in 1912–1913, and is a narrow four-story, four bay wide office building built of brownstone and brick. It features two elegant arches at the first floor and an overhanging cornice.It was added to the National Register of Historic Places in 1980.

SciTech Campus of Harrisburg High school, located in downtown Harrisburg, Pennsylvania, is a regional math and science public school that attracts students from Harrisburg and neighboring school districts. Beginning with the 9th grade, SciTech Campus prepares students for a university curriculum, studying toward degrees in science, engineering and technology. Enrollment is limited to 400 pupils The opportunity to create a unified 9-16 curriculum is unique in the nation and represents a potentially replicable approach to bridging the frequent discontinuity between high school and higher education. The school is a federally designated Title I school. It opened in September 2003. In 2011, the Harrisburg City School District Board changed the name of the school to Harrisburg High School, SciTech Campus. Prior the name was Scitech High.In 2013, Harrisburg High School, SciTech Campus' enrollment was reported as 366 pupils in 9th through 12th grades.

Colonial Theatre, also known as the Lochiel Hotel, is a historic theater and commercial building located at Harrisburg, Dauphin County, Pennsylvania. The building consists of a five-story, brick and frame front section and a rear brick and frame auditorium. The original Colonial Theatre was built about 1836, as a hotel in the Greek Revival style and featured a four columned portico on the Market Street entrance. It was subsequently modified in form and use a number of times. In the 1870s, a mansard roof was added. The rear auditorium was added in 1912, when the building was converted from a hotel to hotel and movie / vaudeville theater. The lobby was remodeled in the 1930s / 1940s in an Art Deco style; the auditorium has Italian Renaissance style detailing. The theater and hotel closed in 1976, and the building used for offices and shops.It was added to the National Register of Historic Places on November 9, 1982.

Strawberry Square is a mixed-use retail and commercial complex located in downtown Harrisburg, Pennsylvania. It is owned and managed by the Harristown Development Corporation (HDC), a non-profit organization.

Harrisburg University of Science & Technology, commonly referred to as Harrisburg University (HU), is a private STEM-focused university in Harrisburg, Pennsylvania, with an additional location in Philadelphia. Founded in 2001 as Harrisburg Polytechnic Institute, it offers STEM-focused degree and certificate programs. Harrisburg University places special emphasis on education in fields related to engineering, applied science and technology and offers 15 bachelor's degrees, 13 master's degrees, and 3 doctoral degrees and certificate programs. The university is accredited by the Middle States Commission on Higher Education.

Downtown Harrisburg is the central core neighborhood, business and government center which surrounds the focal point of Market Square, and serves as the regional center for the greater metropolitan area of Harrisburg, Pennsylvania, United States. Harrisburg's downtown Center City comprises the original 80-acre (320,000 m2) borough laid out in a grid pattern by John Harris in 1785. East–west streets are named and north–south streets are numbered. Market Street, running east–west, is the dividing point between north and south street designations.Harrisburg's Central Business District includes the Pennsylvania State Capitol Complex and other state government offices, the Dauphin County Courthouse and other county government offices, City of Harrisburg offices, Pennsylvania State Museum, federal government offices, and other, non-government related commercial retail and office development. Some residential development, both in apartment high-rises and in the upper floors of mixed commercial/residential use buildings, is also located in the downtown area. Downtown is bordered in the northwest by the mixed commercial/residential use Capitol District, in the west by the Susquehanna River, in the southwest by the largely residential Shipoke neighborhood, in the south by Interstate 83, in the east by Amtrak and Norfolk Southern Railway lines, and in the north by Midtown Harrisburg, a mixed-use commercial and residential neighborhood. Forster Street is usually considered the boundary between Downtown and Midtown Harrisburg. City Island, located in the middle of the Susquehanna River directly west of downtown, is typically considered part of Downtown Harrisburg.

UPMC Harrisburg is a 409-bed urban hospital in Harrisburg, Pennsylvania and part of the University of Pittsburgh Medical Center (UPMC) system. The hospital serves as the hub for the UPMC network, providing advanced care to the residents throughout southcentral Pennsylvania. UPMC Harrisburg features: • A state-of-the-art Labor and Delivery area with a Level III Neonatal Intensive Care Unit. • World-class cardiology care through UPMC Heart and Vascular Institute. • The region’s premier kidney transplant center. • Advanced pediatric care with UPMC Children’s Harrisburg in partnership with nationally recognized UPMC Children’s Hospital of Pittsburgh. • Leading-edge care in neurosciences, women’s care, comprehensive stroke care, and more. This campus is also home to the Alex Grass Medical Sciences Building, which includes: • Bone, Joint, and Spine Institutes • Laboratory services • Maternal Fetal Medicine • Select Medical rehab services UPMC Harrisburg has earned the Magnet® designation. The hospital is a teaching facility providing comprehensive inpatient and outpatient services. Specialties include women's health, cardiovascular care and orthopedic, stroke, and rehabilitative services. Physician residency programs exist on-site for family practice, internal medicine, emergency medicine, obstetrics and gynecology, orthopaedic surgery, and general surgery.In November 2020 UPMC announced the opening of the new pediatric unit at UPMC Harrisburg. The new unit was opened in partnership with the UPMC Children's Hospital of Pittsburgh and consist of 26-pediatric-beds. The unit treats infants, children, teens, and young adults age 0-21. The unit is named "UPMC Children’s Harrisburg" and features telemedicine connections to the main hospital in Pittsburgh.In May 2021 UPMC announced the renaming of UPMC Pinnacle Harrisburg to UPMC Harrisburg, effective May 24.