University of Central Florida College of Dental Medicine

Lake Nona is a 17-square-mile (44 km2, 10,900 acre, 4,400 hectare) mixed-use planned community within the city limits of Orlando, southeast of Orlando International Airport. Being developed by Lake Nona Property Holdings (owned by Tavistock Group), the Lake Nona Region is home to Lake Nona Golf & Country Club. The community is named for a large lake in the northern part. Lake Nona Medical City contains several centers for biomedical research and education including the University of Central Florida College of Medicine and the site of the planned relocation of the College of Nursing, as well as the addition of the University of Central Florida College of Dental Medicine, and the University of Florida College of Pharmacy, which is ranked #5 among all pharmacy schools in the nation. Several other private, governmental, and educational medical centers are located in the area as well. The population of Lake Nona has grown from merely 1,500 in 2000 to over 50,000 people in 2015. Some of the population growth is attributable to immigration from Puerto Rico during the Puerto Rican crisis of 2015.

Nemours Children's Hospital, Florida (NCH) is a freestanding, 130-bed, pediatric acute care children's hospital located in Lake Nona Medical City outside of Orlando, Florida. It is affiliated with the University of Central Florida College of Medicine and is a member of the Nemours Children's Health, one of two freestanding hospitals in the system. The hospital, a multi-year recipient of The Leapfrog Award for quality and safety, provides comprehensive pediatric specialties and subspecialties to infants, children, teens, and young adults aged 0–21 throughout Central Florida and beyond. It features a regional pediatric intensive-care unit and neonatal intensive care units serving both central Florida and the greater Florida regions. The hospital also has a helipad and transport vehicles to transport critically ill patients to and from the hospital. In addition, Nemours Children’s Hospital, Florida features its own Nemours Children’s Hospital Residency Program (established in 2017) and, in partnership with the University of Central Florida’s College of Education started PedsAcademy, the first hospital-based inpatient education and teacher training program.

Red Lake is a lake in Orlando, Florida, United States, near Orlando International Airport, between Lake Nona and Lake Buck.

Lake Nona High School is a public high school in Orlando, Florida, United States. It was a relief school for Odyssey Middle School, Cypress Creek High School, and Oak Ridge High. Lake Nona High School stands as one of the more challenging schools in Orange County due to its rigorous academic workload, significantly high AP Enrollment and its open dual enrollment program through Valencia College. In addition to the school's collegiate focus, students have the ability to attend a fast track nursing program, Health Science Academy starting their freshmen year. The School rating has repeatedly received a high 'A' since 2012. Lake Nona also tops most schools in the district with its high graduation rate of 97.7%.

The University of Central Florida College of Medicine is an academic college of the University of Central Florida located in Orlando, Florida, United States. The VP of Health Affairs and dean of the college is Deborah C. German, M.D. The college consists of a public medical school and the Burnett School of Biomedical Sciences located on the UCF Health Sciences campus in Lake Nona Medical City. The UCF Lake Nona Medical Center, a 64 bed acute care hospital that will serve as the school's main teaching hospital, opened in early 2021. In December 2018, UCF acquired the former Sanford Burnham Prebys Institute facility, which currently houses the UCF Lake Nona Cancer Center.

The 1993 World Cup of Golf took place November 11–14 at the Lake Nona Golf & Country Club in Orlando, Florida, United States. It was the 39th World Cup. The tournament was a 72-hole stroke play team event with each team consisting of two players from a country. The combined score of each team determined the team results. Individuals also competed for the International Trophy. The winners share of the prize money was $300,000 going to the winning pair and $100,000 to the top individual. The United States team of Fred Couples and Davis Love III won (for the second time in a row with the same players in the team) by five strokes over the Zimbabwe team of Mark McNulty and Nick Price. Bernhard Langer of Germany took the International Trophy by three strokes over Couples.

Lake Nona Golf & Country Club is a private residential golf club community in southeast Orlando, Florida. The 600-acre (2.4 km2) community features an 18-hole championship golf course designed by Tom Fazio. Set amidst freshwater lakes and oak, pine and cypress trees, Lake Nona Golf & Country Club offers a range of residences, including custom-built estate homes.

The inaugural Solheim Cup competition took place in Orlando, Florida, United States at Lake Nona Golf & Country Club from November 16 to November 18, 1990. The United States team beat the European team 111⁄2 points to 41⁄2.

The Hilton Grand Vacations Tournament of Champions is a women's professional golf tournament on the LPGA Tour in Florida. It debuted in 2019 at the Four Seasons Golf & Sports Club Orlando in Lake Buena Vista, Florida. The tournament field is limited to winners on LPGA Tour events in the previous two years. As is the case in the past, there is also a pro-am and celebrity tournament, like its predecessor. The top amateurs during the midweek pro-am are invited to play in the main tournament. Each professional is paired with two celebrities or amateurs in the groupings, and celebrities change per round. A Stableford-based system is used for the celebrities and amateurs. For 2022, under new corporate ownership of Hilton Grand Vacations and tournament director Aaron Stewart, son of World Golf Hall of Fame member Payne, the event moves to the Lake Nona Golf & Country Club in Orlando. The move to Lake Nona also eliminates an issue that the 18th hole, a par 3, caused at Four Seasons where the 2020 tournament was pushed to an extra day on Monday morning as the single playoff hole (the 18th) failed to produce a winner, and it was the seventh playing of the 18th hole that finally created a winner. The celebrity division continues to be controlled by Mardy Fish and John Smoltz; the two have won three each. In the United States, the final round of the tournament is broadcast on NBC.

Eagle Creek Golf Club is an eighteen-hole golf course located in near the Lake Nona region of Orlando, Florida. The course has a par of 73 and measures 7,198 yards (6,582 m), containing five par-5 holes and over ninety bunkers. The course is public and includes a 14,000-square-foot (1,300 m2) clubhouse with a pro shop as well as a 120-seat restaurant.

Lake Hart is a census-designated place and an unincorporated area in Orange County, Florida, United States. The population was 542 as of the 2010 census. It is part of the Orlando–Kissimmee Metropolitan Statistical Area.

The Orlando International Airport Intermodal Terminal, also known as the Brightline Orlando Station and South Airport Intermodal Terminal, is an intermodal transit complex under construction at the Orlando International Airport in Orlando, Florida. The new station, which is partially being funded by the Florida Department of Transportation, will serve as the Orlando station for the Brightline inter-city rail service, which will connect Orlando International Airport to downtown Miami via the Florida East Coast Railway. The terminal building and the adjacent parking garage opened on November 17, 2017, while work on the train terminal continues. The facility is connected to the main airport terminal roughly 1 mile (1.6 km) to the north via an automated people mover (APM) system.