Church of the Nativity (Manhattan)

La Salle Academy is a private, Catholic all boys high school run by the Eastern North American District of the Institute of the Brothers of the Christian Schools in the borough of Manhattan, New York City. It was founded by the Christian Brothers in 1848. The school was first named Saint Vincent's School when it opened on Canal Street. It moved to Second Avenue in 1856 and changed its name to La Salle Academy in 1887. In 2010 La Salle relocated to 215 East 6th Street, sharing the building with St. George Ukrainian Catholic School. Various offices are still located in the Second Street building. Throughout its history, La Salle has been home to thousands of "Brothers' boys".

Anthology Film Archives is an international center for the preservation, study, and exhibition of film and video, with a particular focus on independent, experimental, and avant-garde cinema. The film archive and theater is located at 32 Second Avenue on the southeast corner of East 2nd Street, in a New York City historic district in the East Village neighborhood of Manhattan.

The New York City Marble Cemetery is a historic cemetery founded in 1831, and located at 52-74 East 2nd Street between First and Second Avenues in the East Village neighborhood of Manhattan, New York City. The cemetery has 258 underground burial vaults constructed of Tuckahoe marble on the site.The New York City Marble Cemetery, which was the city's second non-sectarian burial place, should not be confused with the nearby New York Marble Cemetery one block west, which was the first, having been established one year earlier. Both cemeteries were designated New York City landmarks in 1969, and in 1980 both were added to the National Register of Historic Places.

Heartbreak was a restaurant in New York City. The restaurant had received a Michelin star.

Club 82, also known as the 82 Club, was a nightclub in Manhattan, New York City that employed female impersonators as entertainers. The nightclub had a second life as a music venue, but was eventually closed.

The New York Marble Cemetery is a burial ground established in 1830 in what is now the East Village of Manhattan. It occupies the interior of the block bounded by 2nd Street, Second Avenue, 3rd Street, and the Bowery. It is entered through an alleyway with an iron gate at each end, located between 41 and 43 Second Avenue. About 2,100 burials are recorded in the cemetery's written registers, most from prominent professional and merchant families in New York City.The New York Marble Cemetery, which was New York City's first non-sectarian burial place, should not be confused with the nearby New York City Marble Cemetery one block east, which is entirely separate, and was established one year later. Both cemeteries were designated New York City landmarks in 1969, and in 1980 both were added to the National Register of Historic Places.

The Horse Trade Theater Group was founded in 1998 in the East Village neighborhood of Manhattan, New York City. It is located at 85 East 4th Street between Second Avenue and The Bowery The three theaters in the group are the Kraine Theater, the Red Room and UNDER St. Marks. These three theaters are the artistic homes to the many Off-Off Broadway theatre artists involved with Horse Trade as resident artists and guest artists.In 2015, Horse Trade Theater Group/The Fire This Time Festival won the Obie Grant at the Obie Awards presented by the American Theater Wing.

KGB is a Soviet-era themed ("Communist chic" ) bar located in the East Village of New York City at 85 E. 4th Street, New York, New York 10003.

Zabb Elee is a Thai restaurant in New York City. The restaurant has received a Michelin star.

La MaMa Experimental Theatre Club (La MaMa E.T.C.) is an Off-Off-Broadway theatre founded in 1961 by Ellen Stewart, African-American theatre director, producer, and fashion designer. Located in Manhattan's East Village, the theatre began in the basement boutique where Stewart sold her fashion designs. Stewart turned the space into a theatre at night, focusing on the work of young playwrights. La MaMa has evolved during its fifty-year history into a world-renowned cultural institution.

New York Theatre Workshop (NYTW) is an Off-Broadway theatre noted for its productions of new works. Located at 79 East 4th Street between Second Avenue and Bowery in the East Village neighborhood of Manhattan, New York City, it houses a 198-seat theatre for its mainstage productions, and a 75-seat black box theatre for staged readings and developing work in the building next door, at 83 East 4th Street.

The East Village/Lower East Side Historic District in Lower Manhattan, New York City was created by the New York City Landmarks Preservation Commission on October 9, 2012. It encompasses 330 buildings, mostly in the East Village neighborhood, primarily along Second Avenue between East 2nd and 6th Streets, and along the side streets. Some of the buildings are located in a second area between First Avenue and Avenue A along East 6th and 7th Streets. The district is based on the one which had been proposed by the Greenwich Village Society for Historic Preservation, with only minor changes, and is the result of a two-year effort to protect the area.Significant buildings which are located within the district include Congregation Adas Yisroel Anshe Mezeritz Synagogue at 415 East 6th Street, the Russian Orthodox Cathedral of the Protection of the Holy Virgin at 59 East 2nd Street, the Community Synagogue at 323 East 6th Street which was originally the Evangelical Lutheran Church of St. Matthew, from which parish which many of the victims of the General Slocum disaster came, the building housing the Pyramid Club at 101 Avenue A, and the Middle Collegiate Church at 112 Second Avenue. In addition the district features many row houses and tenements in the Greek Revival style, and numerous buildings constructed for the German immigrants who dominated the neighborhood in the late 19th and early 20th centuries. The district also includes the theatres on East 4th Street between Second Avenue and the Bowery, which the city has named a cultural district, as well as several remnants of the theatres on Second Avenue when Yiddish theatre thrived there and it was called the "Jewish Rialto". Three buildings contributing to this district were destroyed in the East Village gas explosion on March 26, 2015.: 239–242