St. Mary Church (Grand Street, Manhattan)

The Lower East Side, sometimes abbreviated as LES and sometimes referred to as Loisaida, is a historic neighborhood in the southeastern part of the New York City borough of Manhattan, roughly between the Bowery and the East River from Canal to Houston streets. Traditionally an immigrant, working-class neighborhood, it began rapid gentrification in the mid-2000s, prompting the National Trust for Historic Preservation to place the neighborhood on their list of America's Most Endangered Places.The Lower East Side is part of Manhattan Community District 3, and its primary ZIP Code is 10002. It is patrolled by the 7th Precinct of the New York City Police Department.

Jewish Maternity Hospital was an obstetrics hospital located at 270-272 East Broadway, on the Lower East Side of Manhattan, New York City.

The Bialystoker Synagogue at 7–11 Bialystoker Place, formerly Willett Street, between Grand and Broome Streets in the Lower East Side neighborhood of Manhattan, New York City is an Orthodox Jewish synagogue. The building was constructed in 1826 as the Willett Street Methodist Episcopal Church; the synagogue purchased the building in 1905. The synagogue was designated a New York City Landmark in 1966. It is one of only four early-19th century fieldstone religious buildings surviving from the late Federal period in Lower Manhattan, and is the oldest building used as a synagogue in New York City.

The Henry Street Settlement is a not-for-profit social service agency in the Lower East Side neighborhood of Manhattan, New York City that provides social services, arts programs and health care services to New Yorkers of all ages. It was founded under the name Nurses' Settlement in 1893 by progressive reformer and nurse Lillian Wald.

The Ezras Torah Fund was founded on August 25, 1915 (15 Elul, 5675) at a meeting in Congregation Mishkan Israel in the Lower East Side of New York. The meeting was conducted by members of the Agudas HaRabbanim and the Vaad HaRabbanim of New York. It was an outgrowth of the Central Relief Committee (CRC) that was created to assist Orthodox Jews in Europe during World War I. The CRC had been founded in late 1914 by the Union of Orthodox Jewish Congregations of America with much help from the aforementioned rabbinical organizations. Ezras Torah's role was to specifically assist town rabbis, roshei yeshiva, and yeshivas during the upheaval years of World War I. They eventually broadened their scope to a worldwide level after the war. The founding leadership of Ezras Torah was composed of Rabbi Israel Rosenberg, Rabbi Dr. Philip Klein (aka Hillel HaKohen) and Rabbi Yaakov Eskolsky. Rabbi Rosenberg was president until his passing in 1956. Rabbi Klein was treasurer until his passing in 1926. Rabbi Eskolsky was secretary until 1928. The personality who would be most prominently associated with Ezras Torah was Rabbi Yosef Eliyahu Henkin. He served as the director of Ezras Torah from the summer of 1925 until his passing in 1973.

St. Augustine's Church is located at 290 Henry Street between Montgomery and Jackson Streets on the Lower East Side of Manhattan, New York City. In 2020, it reported 61 members, average attendance of 0, and $71,684 in plate and pledge income.

e-flux is a publishing platform and archive, artist project, curatorial platform, and e-mail service founded in 1998. The arts news digests, events, exhibitions, schools, journal, books, and art projects produced and/or disseminated by e-flux describe strains of critical discourse surrounding contemporary art, culture, and theory internationally. Its monthly publication, e-flux journal, has produced essays commissioned since 2008 about cultural, political, and structural paradigms that inform contemporary artistic production.

Little Fuzhou is a neighborhood in the Two Bridges and Lower East Side areas of the borough of Manhattan in New York City. Little Fuzhou constitutes a portion of the greater Manhattan Chinatown, home to the highest concentration of Chinese people in theWestern Hemisphere. Manhattan's Chinatown is also one of the oldest Chinese ethnic enclaves. The Manhattan Chinatown is one of nine Chinatown neighborhoods in New York City, as well as one of twelve in the New York metropolitan area, which contains the largest ethnic Chinese population outside of Asia, comprising an estimated 893,697 uniracial individuals as of 2017. Starting in the 1980s and especially in the 1990s, the neighborhood became a prime destination for immigrants from Fuzhou, Fujian, China. Manhattan's Little Fuzhou is centered on East Broadway. However, since the 2000s, Chinatown in the neighborhood of Sunset Park became New York City's new primary destination for the Fuzhou immigrants, surpassing the original enclave in Manhattan.

Beth Hamedrash Hagodol (Hebrew: בֵּית הַמִּדְרָש הַגָּדוֹל, "Great Study House") is an Orthodox Jewish congregation that for over 120 years was located in a historic building at 60–64 Norfolk Street between Grand and Broome Streets in the Lower East Side neighborhood of Manhattan, New York City. It was the first Eastern European congregation founded in New York City and the oldest Russian Jewish Orthodox congregation in the United States.Founded in 1852 by Rabbi Abraham Ash as Beth Hamedrash, the congregation split in 1859, with the rabbi and most of the members renaming their congregation Beth Hamedrash Hagodol. The congregation's president and a small number of the members eventually formed the nucleus of Kahal Adath Jeshurun, also known as the Eldridge Street Synagogue. Rabbi Jacob Joseph, the first and only Chief Rabbi of New York City, led the congregation from 1888 to 1902. Rabbi Ephraim Oshry, one of the few European Jewish legal decisors to survive the Holocaust, led the congregation from 1952 to 2003.The congregation's building, a Gothic Revival structure built in 1850 as the Norfolk Street Baptist Church and purchased in 1885, was one of the largest synagogues on the Lower East Side. It was listed on the National Register of Historic Places in 1999. In the late 20th century the congregation dwindled and was unable to maintain the building, which had been damaged by storms. Despite their obtaining funding and grants, the structure was critically endangered.The synagogue was closed in 2007. The congregation, reduced to around 20 regularly attending members, was sharing facilities with a congregation on Henry Street. The Lower East Side Conservancy was trying to raise an estimated $4.5 million for repairs of the building, with the intent of converting it to an educational center. In December the leadership of the synagogue under Rabbi Mendel Greenbaum filed a “hardship application” with the Landmarks Preservation Commission seeking permission to demolish the building to make way for a new residential development. This application was withdrawn in March 2013, but the group Friends of the Lower East Side described Beth Hamedrash Hagodol's status as "demolition by neglect". The abandoned synagogue was "largely destroyed" by a "suspicious" three-alarm fire on May 14, 2017.

The Lowline, formerly known as the Delancey Underground, is a stalled construction project that would have become the world's first underground park in the New York City borough of Manhattan. It is located under the eastbound roadway of Delancey Street on the Lower East Side, in the former Williamsburg Bridge Trolley Terminal adjacent to the Essex Street station (J, M, and Z​ trains) and to the Essex Crossing complex. Construction of the Lowline began in 2019, but was put on hold in 2020 due to lack of funds. The name "Lowline" is a reference to the High Line, an elevated park converted from an abandoned railway.

Ratner's was a famous Jewish kosher dairy (milkhik) restaurant on the Lower East Side of New York City. Since it did not serve meat in deference to the kosher prohibition against mixing milk and meat products, it was often regarded as a complement to Katz's Deli.

Rivington Arms was an art gallery in New York City. Melissa Bent and Mirabelle Marden (daughter of artists Helen and Brice Marden) founded the gallery as a small storefront on Rivington Street in 2001, part of a new wave of galleries opening in the Lower East Side. In 2005, it moved to a larger space on East 2nd Street.The gallery participates in the following art fairs: The Armory Show, Frieze, NADA, and VOLTAshow. It was announced on November 5, 2008 in Artforum that due to business differences, Rivington Arms would be closing its location in January 2009 after they attended the Frieze Art Fair in London.