St. John's Episcopal Church (Wytheville, Virginia)

Haller–Gibboney Rock House is a historic home located at Wytheville, Wythe County, Virginia. It was built in 1822–1823, and is a two-story, five bay late Federal style limestone dwelling. It has a side gable roof and a two-story frame ell terminating in a demi-octagonal end. The Rock House was used as a hospital during the Battle of Wytheville during Civil War. The building houses a museum sponsored by the Wythe County Historical Society.It was listed on the National Register of Historic Places in 1972.

Wytheville Historic District is a national historic district located at Wytheville, Wythe County, Virginia. The district encompasses 245 contributing buildings in the historic core of the town of Wytheville. They are primarily residential and commercial buildings and structures dating from about the 1830s to early 1940s. Notable buildings include the Fleming K. Rich House (1830s), Edith Bolling Galt Wilson Birthplace, Ephraim McGavock House (1858), Holy Trinity Lutheran Church (1876), Wytheville AM&O station (1873), Wythe County Courthouse (1902), George Wythe Hotel (1927), Millwald Theatre (1928), Trinkle Mansion, and Wytheville Municipal Building (1929), The Haller-Gibboney Rock House and St. John's Episcopal Church are located in the district and listed separately.It was listed on the National Register of Historic Places in 1994.

The Wytheville Raid or Toland's Raid (July 18, 1863) was an attack by an undersized Union brigade on a Confederate town during the American Civil War. Union Colonel John Toland led a brigade of over 800 men against a Confederate force of about 130 soldiers and 120 civilians. The location of Wytheville, the county seat of Wythe County in southwestern Virginia, had strategic importance because of a nearby lead mine and the railroad that served it. This mine supplied lead for about one third of the Confederate Army's munitions, while the Virginia & Tennessee Railroad transported Confederate troops and supplies; plus telegraph wires along the railroad line were vital for communications. In addition to logistics of moving the lead to bullet manufacturing facilities, this rail line also connected an important salt works of an adjacent county with the wider Confederacy. Toland's entire brigade was mounted, and consisted of a mounted infantry regiment plus eight companies of cavalry. It approached the small town of Wytheville on the evening of July 18. The community had been warned that a large force of Union horsemen was heading in its direction, and hastily made preparations before the brigade's arrival. While many in the community fled south or hid in their homes, a force of about 120 civilians (including home guard) volunteered to defend their town. The Union cavalry entered the town first, charging in column down the main road that led into town. The men from the cavalry were ambushed by Confederate soldiers, Home Guard, and local citizens. Most of the local men, and women, fired their one–shot muskets from inside their homes and businesses. This type of warfare was considered unconventional at the time. One Union soldier described the road as an "avenue of death".The Union force suffered significant losses. The Union commander, Colonel Toland, was killed. The severely wounded cavalry commander, Colonel William H. Powell, was left to die and became a prisoner of the Confederates. (Powell was also second in command of the entire brigade.) Additional officers and enlisted men were killed, wounded, or missing. The Union after action report listed a total of 86 men killed, wounded, missing, or taken prisoner during the entire expedition—although Confederate leadership believed the Union casualties were much higher. (The entire expedition includes the trips to and from Wytheville.) Approximately 300 horses were lost (killed, wounded, or injured) by the brigade during the raid and retreat—including an estimated 80 killed on the streets of Wytheville. Despite significant losses, the Union brigade was eventually able to secure the town. However, the victory was costly, and the northerners retreated less than 24 hours after entering the small community. A group of soldiers and civilians, less than one third the size of the Union force they opposed, prevented a brigade from destroying vital assets of the Confederacy—a railroad line, telegraph line along the railroad, a lead mine, and possibly a salt mine. After the conflict, Union infantry leaders were critical of the Union cavalry's performance, and men from the cavalry were critical of the infantry leadership's tactics.

Wytheville ( WITH-vihl) is a town in, and the county seat of, Wythe County, Virginia, United States. It is named after George Wythe, a signer of the United States Declaration of Independence, and mentor to Thomas Jefferson. Wytheville's population was 8,211 at the 2010 census. Interstate Highways 77 and 81 were constructed to intersect at the town, long a crossroads for travelers. During the American Civil War, Wytheville had a strategic importance. It was attacked in 1863 (Toland's Raid) and 1865 (Stoneman's 1865 Raid). The town is the birthplace of Edith Bolling Wilson, second wife of President Woodrow Wilson.

Trinkle Mansion is an historic building located in Wytheville, Virginia that is now a four-room bed and breakfast. It is a contributing property to the Wytheville Historic District.

Loretto is a historic home located at Wytheville, Wythe County, Virginia.

Wytheville Community College (WCC) is a public community college in Wytheville, Virginia. It is part of the Virginia Community College System (VCCS) and opened in 1963 as a two-year branch of Virginia Polytechnic Institute & State University. WCC joined the VCCS when it was formed in 1967. The college serves the citizens of Bland, Carroll, Grayson, Smyth (Marion and eastward), and Wythe counties, and the City of Galax. WCC offers nearly thirty academic programs, which include university parallel programs (transfer), occupational-technical programs, and health professions programs. The college awards the associate degree, diplomas, and certificates.

Reed Creek Mill is a historic grist mill at 1565 South Church Street in Wytheville, Virginia. The property includes a c. 1902 wood-frame mill building, a mill dam and raceway, and a c. 1950 storage building. The site has seen industrial use as a mill since 1858; its first mill was torn down late in the 19th century. The present mill building served the local agricultural community until 2004, and has since undergone restoration.The mill was listed on the National Register of Historic Places in 2016.The mill is privately owned and not open to the public.

St. John's Lutheran Church and Cemetery is a historic Evangelical Lutheran church and cemetery and national historic district near Wytheville, Virginia, United States. The church was built in 1854 and is a rectangular, three bay by two bay, frame church sheathed in weatherboard. It measures 45 feet by 55 feet, has a gable roof, and sits on a limestone basement. The auditorium has a gallery. The adjacent cemetery includes a notable group of approximately 30 early-19th century, German-style monuments.It was listed on the National Register of Historic Places in 1978.

Wythe County is a county located in the southwestern part of the U.S. state of Virginia. As of the 2020 census, the population was 28,290. Its county seat is Wytheville.

Petunia is an unincorporated community in Wythe County, Virginia, United States.

Big Survey Wildlife Management Area is a 7,500-acre (30 km2) Wildlife Management Area in Wythe County, Virginia. The preserve's woodland sits on four mountain ridges and divides the watersheds of Reed and Cripple creeks in the New River Valley. Among the trees and shrubs to be found there are rhododendron, azalea, oak, hickory, and pine.Big Survey Wildlife Management Area is owned and maintained by the Virginia Department of Game and Inland Fisheries. The area is open to the public for hunting, hiking, horseback riding, and camping. Access for persons 17 years of age or older requires a valid hunting permit, fishing permit, or WMA access permit.