John W. Lederle Graduate Research Center

The Ellis Drive Historical Area is an older section of the UMass Amherst containing many of the university's earliest laboratory buildings. Several of these buildings have since been converted for other uses, but research still continues in many of them to this day.

The Draper Hall Annex is a single-story office building which houses emergency medical services at the University of Massachusetts Amherst. The building is adjoined to Draper Hall, and has served as an office space, classroom, and at one time, home to the university's polymer science research.

Marston Hall is an academic building on the campus of the University of Massachusetts Amherst. It houses the Dean of Engineering and parts of the Departments of Civil and Environmental Engineering, Mechanical and Industrial Engineering, and Electrical and Computer Engineering.

The University of Massachusetts Amherst College of Engineering is one of the schools and colleges at the University of Massachusetts Amherst. It was established on September 1, 1947 as the School of Engineering and now considered as the best public engineering school in New England, enrolling 2250 undergraduate students and 610 graduate students including 300 M.S. students and 310 Ph.D. students for the 2018–2019 school year. The College of Engineering at UMass Amherst has eight buildings, including the Elab II, research facilities, computer labs, and graduate offices. It has more than 16,000 living alumni around the world.

The College of Social and Behavioral Sciences (SBS) at the University of Massachusetts Amherst is home to the School of Public Policy as well as nine academic departments offering 13 undergraduate majors, 11 areas of Master's and doctoral study, and a number of graduate certificate programs. The college bridges science and liberal arts, encouraging students to pursue cross-disciplinary studies, take classes outside their chosen major, and participate in research projects with faculty mentors. As of 2023, SBS enrolled 3,591 students with a student/professor ratio of 16:1.

The University of Massachusetts Amherst School of Public Health and Health Sciences is a school at the University of Massachusetts Amherst.

Murray D. Lincoln Campus Center is a high-rise building on the University of Massachusetts Amherst campus, in Amherst, Massachusetts.

The Stockbridge School of Agriculture offers Associate of Science, Bachelor of Science, and graduate degrees as an academic unit of the University of Massachusetts Amherst campus. It was founded as part of the Massachusetts Agricultural College (now University of Massachusetts Amherst) in 1918. The school's main facility and school symbol is Stockbridge Hall, named after Levi Stockbridge, a founder of Massachusetts Agricultural College and its first professor of agriculture; however, its faculty occupies various buildings on the University of Massachusetts campus, including Agricultural Engineering, Bowditch, Clark, Fernald, French, Stockbridge, and West Experiment Station. Research, education, and extension activities occur at the UMass Cold Spring Orchard Research & Education Center, the Hadley Farm (Stockbridge Stables), the Joseph Troll Turf Research Center, the UMass Vegetable & Agronomy Research Farm, and the CNS Greenhouses.

The Blue Wall is a former dive bar and current food court at the University of Massachusetts Amherst. Opening inside the Murray D. Lincoln Campus Center in the 1970s, the bar made upwards of $600,000 in the late 1970s (over $2,300,000 in 2013 dollars), and went through 1,800 kegs a year. This made it one of the largest beer-consuming establishments in the Northeastern United States. Following the raising of the drinking age to 21 in the United States, the bar experienced a decline in sales, before finally going dry in the 1980s. In the early 2000s, alcohol was again served, although it proved to be unprofitable. In 2014, the dining facility underwent an almost year-long nineteen million dollar renovation, which saw it connect to a nearby restaurant and increase seating capacity by thirty percent. The new combined area totals 42,000 square feet and has space for 900 customers. The campus center also includes several other food and drink options, including the UPub (bar for 21+), the grab and go Marketplace, and People's Organic Coffee.

Flint Laboratory is an academic building and a former dairy laboratory at the University of Massachusetts Amherst. It was the first building of the Ellis Drive "agricultural group", including Stockbridge Hall and an unbuilt hall for agricultural mechanics. At the time of its completion, the laboratory was considered to be "one of the best equipped dairy buildings in the United States" and was described as "a model for the whole country" in one edition of the Works Progress Administration guidebook to Massachusetts. The building was named after Charles L. Flint, the university's fourth president, the first secretary of the state board of agriculture, a lecturer on dairy farming, and a prolific agricultural writer who wrote a well-received textbook on "Milch Cows" in the late 19th century. Today the building has been almost entirely converted to office space for the university's Department of Hospitality and Tourism Management, however the former "dairy bar" has been repurposed as a restaurant known as Fletcher's Café, which is run by students of the hospitality program.

The campus of the University of Massachusetts Amherst is located nearly entirely in Amherst, Massachusetts, United States, with a portion located in Hadley. Founded on 310 acres in rural Western Massachusetts, the campus has grown to nearly 1,450 acres.

The University of Massachusetts Amherst Elaine N. Marieb College of Nursing is a nursing college at the University of Massachusetts Amherst.