Potter Stewart United States Courthouse

The United States District Court for the Southern District of Ohio (in case citations, S.D. Ohio) is one of two United States district courts in Ohio and includes forty-eight of the state's eighty-eight counties–everything from the Columbus area southward. Appeals from the court are taken to the United States Court of Appeals for the Sixth Circuit at Cincinnati (except for patent claims and claims against the U.S. government under the Tucker Act, which are appealed to the Federal Circuit). The United States Attorney's Office of the Southern District of Ohio represents the United States in civil and criminal litigation in the court. On February 12, 2014, Peter C. Tobin was confirmed to be the United States Marshal. As of November 2021, the United States Attorney is Kenneth L. Parker.

East Fourth Street Historic District is a registered historic district in Cincinnati, Ohio, listed in the National Register of Historic Places on February 22, 1988. It contains a row of 3 side-by-side contributing buildings dating circa 1860. The former headquarters Cincinnati Gas & Electric Company, completed in 1929, although not a contributing property, stands next door to the cluster of buildings at the southwest corner of Fourth and Main streets. Its tower can be seen in the left side of the image.

The Formica Building is a mixed-use building in Cincinnati, Ohio.

The Mercantile Library of Cincinnati is a membership library located in downtown Cincinnati, Ohio. The name of the Library refers not to the type of items in its collection but to the forty-five merchants and clerks who founded it on April 18, 1835 as the Young Men's Mercantile Library Association.

The Federal Reserve Bank of Cleveland Cincinnati Branch Office is one of two Federal Reserve Bank of Cleveland branch offices (the other is in Pittsburgh). The Cincinnati Office of the Federal Reserve Bank of Cleveland provides currency distribution services for financial institutions in multiple Reserve Districts.James M. Anderson is the current chairman.

On September 6, 2018, a mass shooting occurred in Cincinnati, Ohio, United States. At 9:10 AM EDT, Omar Santa Perez, 29, opened fire with a Taurus PT-809E 9mm pistol equipped with standard and hollow-point ammunition, in the lobby of the Fifth Third Center in Cincinnati, Ohio, killing three people. He was then shot and killed by responding police officers.

Fifth Third Center is a skyscraper located in downtown Cincinnati, in the U.S. state of Ohio on Fountain Square. The building has 30 stories and rises to a height of 423.23 feet (129.00 m). It is currently the fifth-tallest building in Cincinnati. It was designed by Harrison & Abramovitz and completed in 1969. The building serves as the corporate headquarters for Fifth Third Bank. On September 6, 2018, the building was the site of a mass shooting, in which four people were killed, including the suspect. Two others were also injured in the shooting.

The PNC Center is a 108-meter (354 feet) tall office building located in Cincinnati, Ohio. It is located primarily in the Central Business District and borders Main Street and East Fifth Street. The building's 27 floors are used for office and commercial use. On the southeast corner of Fifth and Main streets is a public plaza. Built in 1979, this skyscraper was the tallest completed in Cincinnati during the 1970s decade. It initially served as headquarters of Central Trust Bank, which PNC acquired in 1988. With the acquisition, PNC also became the lead tenant of the historic PNC Tower, Central Trust's headquarters before the 1979 building was constructed. The building's exterior is typical of 1970s architecture. It features a lightly colored exterior wall with tinted rectangular windows. Unusual for architecture of the time, there are a number of setbacks in the building, both horizontally and vertically. The building has no crown or topped area which is also typical of 1970s architecture. The roof is flat. The building was designed by Skidmore, Owings & Merril.

The Maisonette, now defunct, was North America’s most highly rated restaurant before it closed its doors on July 25, 2005.Owned and operated by the Comisar family and located since 1966 at 114 E. 6th Street in Cincinnati, Ohio, the Maisonette boasted the longest running streak of five-star awards, the highest designation given by Mobil Travel Guide. That streak ended at 41 years when the Maisonette closed. Opinions vary on what caused the restaurant to lose its luster. Fewer people frequented the luxury restaurant, operating costs increased, and the City of Cincinnati refused to offer a tax break to the downtown landmark. The Maisonette had plans to move to Kenwood, a suburb of Cincinnati, where it would reinvent its image, hoping to attract a more modern, younger crowd; however, the Hamilton County Planning Commission rejected zoning for the proposed Sycamore Square project, a $60 million development that included a relocated Maisonette as the anchor tenant. Instead, the top-rated French cuisine restaurant auctioned off all of its assets through a two-day auction hosted by the Great American Group auction firm. The most expensive item sold at auction was the Maisonette's name/logo, which sold for $35,000. The restaurant originally opened in 1949. In 1964 the restaurant won its first 5-star rating from Mobil. In 2013, the Phoenix Restaurant Group located in Cincinnati, OH acquired the trademark for The Maisonette in order to preserve and safeguard its history and reputation.

Gwynne Building is a registered historic building in Cincinnati, Ohio, listed in the National Register on August 3, 1979.

The Renaissance Cincinnati Downtown Hotel (previously known as the Bartlett Building and the Union Trust Building) is a historic building in downtown Cincinnati, Ohio, located at 4th & Walnut Street. The 19-story tower was the tallest building in the state for 3 years until completion of the Fourth & Walnut Center. The Union Trust Building was dedicated January 1, 1901. In 1985, the skyscraper was renamed for its new owners, The Bartlett Company. The company sold the building for $8 million in 2006. At the time, it was also home to Fosdick & Hilmer (engineering firm), an American Airlines reservation center, CVS Pharmacy, Phillip Bortz Jewelers, and Jimmy John's among many others. In June 2010, after a second failed sale of the building, Fifth Third Bank foreclosed on the property and all tenants vacated the building.An affiliate of Columbus real estate firm E.V. Bishoff Co. acquired the building on February 8, 2013 for $535,000, ending more than five years of legal limbo for the vacant tower. In May of that same year, it was announced that the building would be converted into a $33 million hotel. On July 25, 2014, Columbia Sussex reopened the building as the Renaissance Cincinnati Downtown Hotel with 283 rooms, 40 suites, eight meeting rooms, and nearly 14,400 square feet of total meeting space. It became the third Renaissance Hotels branded hotel in Ohio. The onsite restaurant has been branded D. Burnham's, a tribute to the buildings architect Daniel Burnham.

The Fourth & Walnut Center (previously known by the names Clopay Building and the First National Bank Building) is a building in Cincinnati, Ohio. It was the tallest in the state from 1904 - 1913. The building was designed by D.H. Burnham and Company and completed in 1904. The architect Daniel Burnham of Chicago designed the Clopay Building (a combination of the words clothing and paper) in the Chicago school. The building was listed on the National Register of Historic Places in 2017.