Museo Francisco Pancho Coimbre

The Antiguo Cuartel Militar Español de Ponce or "El Castillo" (English: Old Spanish Military Headquarters in Ponce or "The Castle") is the only structure directly related to the events of the land defense of Puerto Rico during the 1898 American invasion of the Island. The historic building dates from 1894 and is located on Calle Castillo in Ponce, Puerto Rico, in the city's historic district. The structure was listed on the U.S. National Register of Historic Places on 14 May 1987.

Quinto (Barrio Quinto) is one of the 31 barrios of the municipality of Ponce, Puerto Rico. Together with Primero, Segundo, Tercero, Cuarto, and Sexto, Quinto is one of the municipality's six original urban barrios. It was organized in 1878.

Campo Atlético Charles H. Terry (English: Charles H. Terry Athletic Field) or, simply, El Charles H. Terry, is the oldest continuously functioning athletic field and baseball park in Puerto Rico, and the second oldest in the Caribbean. The field is located in the city of Ponce and has a capacity of several thousand spectators. It is located next to the Francisco Pancho Coimbre Sports Museum.

Ponce Honra a su Maestra: Lolita Tizol is a marble statue to the memory of Puerto Rican music schoolteacher Lolita Tizol. It is located on Bolevar Miguel Pou, at the fork of Isabel and Lolita Tizol streets, in Ponce, Puerto Rico. The statue has abundant visibility as it is located in an open area of Tricentennial Park.

Casa Font-Ubides (English: Font-Ubides House), also known as the Residencia Monsanto (English: Monsanto Residence) is a historic building located on the north side of Castillo Street in Ponce, Puerto Rico, in the city's historic district. The building dates from 1913. It was designed by the architect Blas Silva. The architecture consists of 19th Classical revival and Art Nouveau architectural styles. The building is of architectural significance for its aggressive incorporation of curvilinear forms and ornaments. The complete preservation of the original architecture of the Monsanto Residence, its unique design amongst the houses of Ponce, and its location within the historic urban core of the city qualify it as one of a series of grand houses and an integral part of the character of Ponce.

Parque del Tricentenario is a passive urban park in the city of Ponce, Puerto Rico. The park was built to commemorate the 300th anniversary of the founding of the city. It was inaugurated during the mayoral administration of mayor Rafael Cordero Santiago.

The Puente de los Leones (literally, Bridge of the Lions) is a historic bridge in Ponce, Puerto Rico, joining Barrio Tercero to Barrio San Antón and Barrio Machuelo Abajo. It is also the city's best known bridge. The bridge is at the western terminus of Bulevar Miguel Pou, the main gateway to the Ponce Historic Zone. The Art Deco bridge carries four lanes of vehicular traffic from the two-way Miguel Pou Boulevard. It crosses Río Portugués connecting Barrio Tercero to the west with Barrios Machuelo Abajo and San Anton to the east. It is located 0.5 km east of Plaza Las Delicias.

The Museo de la Música Puertorriqueña (English: Museum of Puerto Rican Music) is a museum in Ponce, Puerto Rico, that showcases the development of Puerto Rican music, with displays of Taíno, Spanish, and African musical instruments that were played in the romantic danza genre, the favorite music of 19th-century Puerto Rican high society, as well as the more African-inspired bomba and plena styles. Also on display are memorabilia of composers and performers. The Museum traces the rich musical history of Puerto Rico through memorabilia of prominent musicians and displays of the musical instruments associated with the three genres of music that originated in this Caribbean island.The building that houses the museum is known as Casa Serrallés and it was the former downtown residence (as opposed to his hilltop Castillo Serrallés structure) of Juan Eugenio Serrallés and his family, owners of Destilería Serrallés and makers of the Don Q rum.

Fundación Biblioteca Rafael Hernández Colón (English: Rafael Hernández Colón Foundation Library) is a gubernatorial library and museum that records the political life of three-term governor of Puerto Rico, Rafael Hernández Colón. It was founded in 1992 and in September 2015 it moved to its current location at the southeast corner of Calle Mayor and Calle Castillo in Ponce, Puerto Rico, in the Ponce Historic Zone.

The Parque Ecológico Urbano (English: Urban Ecological Park), also known as Parque Ecológico de Ponce, is a passive park in Ponce, Puerto Rico. The park was designed by Bonin Orozco Arquitectos and was inaugurated on 19 September 2012. The park is unique in that it was designed to create a "green lung" in the city by using ecological mindset in its entirety, from the construction materials used to the design and other areas as well. Except for one tree that got relocated within the project, the new park made use of all the existing trees and shrubs as they existed on the site prior to the development of the park.

Puente La Milagrosa is a historic bridge in Ponce, Puerto Rico. The Art Deco bridge carries two lanes of vehicular traffic for the two-way Calle Guadalupe (PR-14R). It runs west to east and crosses Río Portugués connecting Barrio Quinto in the west to Barrio Machuelo Abajo in the east. It is located 0.7 km northeast of Plaza Las Delicias. It is part of the historic Carretera Central.

Ponce Servicos, formerly Plaza del Mercado Juan Bigas, is a brutalist municipal building located Ponce, Puerto Rico. It is the largest building in the municipality in terms of footprint area and the only one that occupies an entire city block. The structure was built in 1981 as a way to provide a modern, air-conditioned, structure for the merchants and shoppers of the historic but aging Plaza de Mercado Isabel II building, while the latter underwent restoration. On its opening day it was named Plaza del Mercado Juan Bigas, in honor of Juan Bigas Moulins, the Ponce businessman by that name. Upon its opening, some of the former fruits-and-vegetables merchants from the old Plaza del Mercado Isabel II building moved in, but many did not. Objections ranged from rent being too high to not providing the friendly atmosphere of the old Isabel II building provided because many perceived this brutalist architecture building as one that did not carry on the important city historic values conveyed by the old Art Deco Plaza del Mercado Isabel II building. In spite of these objections, the new building was used as a fruits-and-vegetables farm market plaza for 26 years, until 2007, when the restoration of the older Isabel II building was completed. On that year (2007), Plaza del Mercado Juan Bigas building was vacated, and merchants moved back to restored Plaza del Mercado Isabel II building, and the building came to be known simply as the Juan Bigas Building. The Juan Bigas building then sat unused for three years, until 2010. In that year, after negotiations between the central and municipal governments, the Government of Puerto Rico transferred the structure to the Ponce Municipal Government. The Ponce municipal government reconditioned the building, now no longer called Plaza del Mercado Juan Bigas, but simply Edificio Juan Bigas (Juan Bigas Building) for use as office space for several municipal agencies. In October 2013, the Ponce Municipal Government reopened the building as a multi-agency municipal building offering a mix of municipal services to its residents and christened it "Ponce Servicios" (Ponce Services).