John N. and Elizabeth Taylor House

The West Broadway Historic District in Columbia, Missouri is composed of 21 residential properties located facing Broadway on a plateau west of downtown. The district contains some of the largest and best preserved historic homes in Columbia.The district was listed on the National Register of Historic Places in 2010 and includes the previously listed John N. and Elizabeth Taylor House.

Heritage Academy is a private, co-educational Christian school in Columbia, Missouri, USA, which employs the University-Model approach to education and is certified by the National Association of University-Model Schools (NAUMS). This approach seeks to combine the strengths of the home with professional instruction. It also provides a larger community for homeschooled students that would be unavailable to them a purely homeschooling environment. Students at Heritage Academy attend classes on campus from one to three days each week. On the other days, they complete assignments under the supervision of a parent or parents.

The Smithton Land Company was a group of American pioneers who in 1818 established the frontier village of Smithton, Missouri in the Boonslick region of Missouri, then the Missouri Territory. In 1821 the settlement was renamed Columbia, Missouri and relocated slightly East of its original location. Smithton was the first county seat of Boone County. The company and town were named after Thomas Adams Smith, the receiver of the land office in Franklin, Missouri.Smithton’s origin begins with the settlement of American pioneers from Kentucky and Virginia in an early 1800s region known as the Boonslick. Before 1815 settlement in the region was confined to small log forts because of the threat of Native American attack during the War of 1812. When the war ended settlers came on foot, horseback, and wagon, often moving entire households along the Boone's Lick Road and often bringing enslaved African Americans. By 1818 it was clear that the increased population would necessitate a new county be created from territorial Howard County. The Mouniteau Creek on the west and Cedar Creek on the east were obvious natural boundaries.Believing it was only a matter of time before a county seat was chosen, the Smithton Land Company was formed to purchase over 2,000 acres (8.1 km2) to established the village of Smithton near the present-day intersection of Walnut and Garth. In 1819 Smithton was a small cluster of log cabins in an ancient forest of oak and hickory; chief among them was the cabin of Richard Gentry, a trustee of the Smithton Company who would become first mayor of Columbia. In 1820 Boone County was formed and named after the recently deceased explorer Daniel Boone. The Missouri Legislature appointed John Gray, Jefferson Fulcher, Absalom Hicks, Lawrence Bass, and David Jackson as commissioners to select and establish a permanent county seat. Smithton never had more than twenty people, and it was quickly realized that well digging was difficult because of the bedrock. Springs were discovered across the Flat Branch Creek, so in the Spring of 1821 Columbia was laid off and the inhabitants of Smithton moved their cabins to the new town. The first house in Columbia was built by Thomas Duly in 1820 at what would become Fifth and Broadway. They renamed the settlement Columbia—a historical name for the United States. Columbia's permanence was ensured when it was chosen as county seat in 1821 and the Boone's Lick Road was rerouted down Broadway.

The Columbia Cemetery in Columbia, Missouri has been in use as a cemetery since 1820. The cemetery historically contains, White, African-American, and Jewish (Beth Olem Cemetery, Beth Shalom Cemetery) sections. Located in the cemetery are a vernacular stone receiving vault (1887), and a Romanesque Revival style mausoleum (1911).Located on Broadway just west of Downtown Columbia, the cemetery contains many burials of prominent people associated with Missouri history, the University of Missouri, or the city of Columbia. It was listed on the National Register of Historic Places in 2007. It is still an operating cemetery with room for many more burials and celebrated its 200th anniversary in 2020.

Welch Hall is a historic residence located at 24 E Stewart Rd on Oak Hill in Columbia, Missouri. The residence is home to the University of Missouri chapter of Sigma Alpha Epsilon. The site was recognized by the Columbia Historic Preservation Commission as one of the city's Most Notable Historic Properties in 2004. It was nominated for the National Register of Historic Places in 2014.

The Sigma Alpha Epsilon Building is a historic Sigma Alpha Epsilon fraternity house located near the University of Missouri at Columbia, Missouri. It was built about 1908 to house the Welch Military Academy. The building took its present form in 1929 under the direction of architects Fred Wallace of Marchall and Brown. It is a 2+1⁄2-story Neo-Classical Revival style brick building with a "T"-plan. Its front facade features a central pedimented portico with six two-story stone Ionic order columns.It was restored between 1965 and 1966 after a fire. The property was added to the National Register of Historic Places in 2014.

The Columbia station, also known as Missouri, Kansas, and Texas Railroad Depot or Katy Station, was built in 1909 by the Missouri–Kansas–Texas Railroad in downtown Columbia, Missouri. The station was one of two train stations serving Columbia in the 20th century, the other being the Wabash Railroad Station and Freight House constructed the same year. The building is the terminus of the MKT Trail, a rails-to-trails project that was built on the former spur of the railroad. Having housed a popular local restaurant named "Katy Station" after the building, it now houses a bar name "Shiloh's."The property was listed on the National Register of Historic Places in 1979.

Second Baptist Church is a historic Baptist church located at 4th St. and Broadway in Columbia, Missouri. It was built in 1894, and has Gothic Revival and Romanesque Revival design elements. The church was founded by newly emancipated slaves many of whom were members of First Baptist Church. It was added to the National Register of Historic Places in 1980.

Frederick Douglass High School is an alternative public high school located in Columbia, Missouri. Douglass enrolls students 9-12 from throughout the Columbia Public Schools District. The school competes in MSHSAA 4A. Their sports include basketball and track and field. The school differs from typical high schools due to providing programs including child development and parenting classes and a day care facility. It was built in 1917, and is a two-story, Classical Revival style brick building on a raised basement. The building was listed on the National Register of Historic Places in 1980 as Fred Douglass School. Recently, it was closed, restored, and modernized, reopening in the Fall of 2017. It is one of four High Schools in the Columbia Public School District.

The John W. Boone House, also known as the Stuart P. Parker Funeral Home, is a historic home located at Columbia, Missouri. It was built about 1890, and is a two-story frame house that measures roughly 46 feet by 45 feet. It was the home of ragtime musician John William 'Blind' Boone. The home, which is owned by the City of Columbia, had fallen into a state of severe disrepair, but is now under restoration It was listed on the National Register of Historic Places in 1980.

Islamic Center of Central Missouri is a mosque located in Columbia, Missouri. Established in 1983, it is the first Islamic center in the state of Missouri.

The Columbia Agriculture Park is a public park in Columbia, Missouri, focusing on food production and distribution. It is home to the Columbia Farmers Market, and contains a pavilion with space for 98 vendors. The park opened in 2019 and by 2021 will include an interactive urban farm, demonstration gardens and orchards, a commercial kitchen, event space, a recreational trail, amphitheater, outdoor classroom, and playground. It will also house the offices of the Columbia Center for Urban Agriculture and a resource center. The park was created by a public-private partnership between Columbia Parks and Recreation, the Columbia Farmers Market, the Columbia Center for Urban Agriculture, and Sustainable Farms and Communities. It is the first of its kind in Missouri.