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Melzo is an unincorporated community in southern Jefferson County, in the U.S. state of Missouri. The community is located on Missouri Route E just north of the Jefferson-St. Francois county line. DeSoto is eight miles to the north and Bone Terre is approximately six miles to the south.

Big River Township is an inactive township in St. Francois County, in the U.S. state of Missouri.Big River Township was erected in 1863, taking its name from the Big River.

Lake Timberline is an unincorporated community and census-designated place (CDP) in St. Francois County, Missouri, United States. The community is built around several reservoirs built in the valleys of Bee Run and Primrose Creek, southwest-flowing tributaries of the Big River, which in turn flows northwest to the Meramec River. The community is in northern St. Francois County, bordered to the north by Jefferson County. It is northwest of U.S. Route 67, 6 miles (10 km) north of Bonne Terre, 19 miles (31 km) southwest of Festus, and 53 miles (85 km) southwest of St. Louis. The community was first listed as a CDP prior to the 2020 census.

Silver Springs is an unincorporated community in St. Francois County, in the U.S. state of Missouri.

Mill Creek is a stream in Washington and St. Francois counties of eastern Missouri. It is a tributary of the Big River. The stream source is located at: 37°56′29″N 90°43′25″W near Mineral Point and the confluence with Big River is at: 38°02′10″N 90°37′11″W just south of Blackwell.

Blackwell is an unincorporated community in a small part of Washington County and the extreme northern section of St. Francois County, Missouri, United States. It is located approximately seven and a half miles south of De Soto. A variant name was "Blackwell Station". A post office called Blackwells Station was established in 1858, and the name was changed to Blackwell in 1885. The community has the name of Lavinia Blackwell and Margaret Blackwell, first settlers.

Cabanne Course is a stream in St. Francois County in the U.S. state of Missouri.Cabanne Course has the name of the local Cabanne family.

Bee Run is a stream in northern St. Francois County in the U.S. state of Missouri. It is a tributary of the Big River. The stream headwaters arise on a hillside adjacent to an old railroad tunnel at 38°00′22″N 90°30′03″W. The stream flows southwest generally parallel to and northwest of Missouri Route 67 past the community of Silver Springs and the Lake Timberline area to its confluence with the Big River about three miles north of Bonne Terre at 37°58′00″N 90°33′32″W.Bee Run was so named on account of honeybees near its course.

Coonville Creek is a stream in St. Francois County in the U.S. state of Missouri.Coonville Creek was so named on account of raccoons near its course.

Summer Set is an unincorporated community and census-designated place (CDP) in Jefferson County, Missouri, United States. It is in the southern part of the county, 3 miles (5 km) south of De Soto. It is a residential community built around three artificial lakes: Summerset Lake, Winterhaven Lake, and Spring Lake. Summer Set was first listed as a CDP prior to the 2020 census.

St. Francois State Park is a public recreation area occupying 2,735 acres (1,107 ha) of land five miles (8.0 km) north of Bonne Terre in St. Francois County, Missouri. The state park features a campground, trails for hiking and horseback riding, and fishing on the Big River. The 49-acre (20 ha) Coonville Creek Natural Area, made up of Coonville Creek and its narrow valley, is found within the park's boundaries.

Valle Township is an inactive township in Jefferson County, in the U.S. state of Missouri.Valle Township derives its name from Valles Mines.