Central West End, St. Louis

Rosati-Kain High School is an all-girls Catholic high school in St. Louis, Missouri. Rosati-Kain is accredited as a college preparatory school by the North Central Association, the Missouri Department of Education, and the Roman Catholic Archdiocese of Saint Louis.

The Cathedral Basilica of Saint Louis, also known as the Saint Louis Cathedral, is a Catholic cathedral in the Central West End neighborhood of St. Louis, Missouri. Completed in 1914, it is the mother church of the Archdiocese of St. Louis and the seat of Archbishop Mitchell T. Rozanski. The cathedral is named for Saint Louis and was designated a basilica by Pope John Paul II in 1997.The cathedral was built as a replacement for the previous cathedral, the Basilica of Saint Louis, King of France, located along the Mississippi River. Although workers began clearing ground for the building on May 1, 1907, dedication of the cathedral and its first Mass did not take place until October 18, 1914, when the superstructure was complete. Consecration of the church took place more than a decade later on June 29, 1926. The church is known for its large mosaic installation (which is one of the largest in the Western Hemisphere), and for its burial crypts.

The Butler House is a turreted, brick house built in 1892 for prominent St. Louis tobacco manufacturer James Gay Butler. It was designed in the Queen Anne style by Albert Knell, a Canadian architect.

The Archdiocese of St. Louis (Latin: Archidiœcesis Sancti Ludovici) is a Latin Church ecclesiastical territory or archdiocese of the Catholic Church that covers the City of St. Louis and the Missouri counties of Franklin, Jefferson, Lincoln, Perry, Saint Charles, Saint Francois, Ste. Genevieve, St. Louis, Warren, and Washington. It is the metropolitan see of the ecclesiastical province containing three suffragan sees: Diocese of Springfield-Cape Girardeau, the Diocese of Jefferson City, and the Diocese of Kansas City-Saint Joseph. It is led by Archbishop, Mitchell Thomas Rozanski, formerly the Bishop of Springfield in Massachusetts. The archdiocesan cathedral is the Cathedral Basilica of St. Louis. The original cathedral and mother church is the Basilica of St. Louis, King of France.

McDonnell Genome Institute (The Elizabeth H. and James S. McDonnell III Genome Institute) at Washington University in St. Louis, Missouri, is one of three NIH funded large-scale sequencing centers in the United States. Affiliated with Washington University School of Medicine and the Alvin J. Siteman Cancer Center, the McDonnell Genome Institute is creating, testing and implementing new approaches to the study of genomics with the goal of understanding human health and disease, as well as evolution and the biology of other organisms.

The Sanitol Building, at 4252-64 Laclede Ave. in St. Louis, Missouri, was built in 1906. It was listed on the National Register of Historic Places in 1985.It is a two-story red-brown brick building, on a limestone foundation, which was built as a factory and offices building for the Sanitol Chemical Laboratory Company. It was designed by architect George W. Hellmuth, and it includes Classical Revival detailing.

Goldfarb School of Nursing at Barnes–Jewish College is a college of nursing located in St. Louis. It has one campus: located at Washington University's Medical School and Barnes-Jewish Hospital campus.

Listed below are notable or preserved private residences in the United States of significant American writers. These writers' homes, where many Pulitzer Prize-winning books were written, also inspired the settings of many notable poems, short stories and novels.

The Kate Chopin House, located at 4232 McPherson Avenue in St. Louis, Missouri, is the former home of author Kate Chopin. The house was built in 1897 by contractor Oscar F. Humphrey. Chopin moved to the house in 1903 and lived there until her death in 1904; while living in the house, she wrote her last poem and story. Chopin grew up in St. Louis before moving to Louisiana with her husband; after his death, she returned to St. Louis, where she began her writing career. Her stories discussed the evolving role of women in American society, and contemporary literary critics considered her one of the most significant St. Louis authors of the period. The house at 4232 McPherson is her only surviving former residence in St. Louis.The house was added to the National Register of Historic Places on February 14, 1986.

Bel Air Motel, also known as Bel Air West, was a historic building and motel in the Central West End neighborhood in St. Louis, Missouri, U.S.. It is listed as one of the National Register of Historic Places since 2009. This building is now known as a Holiday Inn Express after a remodel in 2014.

Cortex Innovation Community, Cortex Innovation District, or Cortex is an innovation district in the Midtown neighborhood of St. Louis, Missouri. A 200-acre hub for technology and biological science research, development, and commercialization, Cortex is a main location for the city's technology startup companies. It is near Washington University School of Medicine, Saint Louis University, and Barnes-Jewish Hospital. Cortex officials say their master plan calls for $2.3 billion of construction, producing more than 4.5 million square feet of mixed-use development to house 13,000 jobs in technology.Cortex 3.0, a $170 million expansion was completed in fall 2018.

Second Presbyterian Church is a historic church at 4501 Westminster Place in St. Louis, Missouri.