Federal Building and United States Courthouse (Wheeling, West Virginia, 1907)

Charles W. Russell House is a historic home located at Wheeling, Ohio County, West Virginia. It was built in 1848, and is a 2+1⁄2-story, four-bay-wide, Greek Revival-style brick dwelling. It was constructed as an office and residence for attorney Charles W. Russell (1818-1867). It was part of the military headquarters established at Wheeling during the first winter of the American Civil War.It was listed on the National Register of Historic Places in 1993. It is located in the East Wheeling Historic District.

First opening its doors in 1904, Victoria Theater is the oldest operating theater in West Virginia. Located in the registered historic market district of the city of Wheeling, the Victoria is a ~800 seat Victorian style theater with many Beaux-Arts design influences. In 1934, the Victoria Theater served, for a short period, as home to the WWVA Jamboree (later renamed "Jamboree USA"), the second-longest running radio program in the U.S.The Victoria Theater is also known as the Victoria Vaudeville Theater. It is located at Market Street between 12th and 14th streets in downtown Wheeling, West Virginia. The theater today serves as a venue for live acts, including an Elvis impersonator, country, bluegrass, rock, and gospel music. Magician Dennis Regling also performs regularly at the Victoria.

The Cathedral of Saint Joseph of Wheeling or Saint Joseph's Cathedral is the seat of the bishop of the Catholic Diocese of Wheeling-Charleston. In addition to being the seat of the bishop, the cathedral is home to the oldest congregation in the city of Wheeling, West Virginia. The cathedral is a contributing property to the East Wheeling Historic District on the National Register of Historic Places.The current pastor of the cathedral is the bishop of the Diocese of Wheeling-Charleston, the Most Reverend Mark E. Brennan. The current priest in residence is Father Justin Golna.

Monroe Street East Historic District is a national historic district located at Wheeling, Ohio County, West Virginia. The district encompasses six contributing buildings. They are a Greek Revival style church built in 1837, a Roman-Tuscan style dwelling dated to 1852 and known as the Paxton-Reed House, and an eclectic 1881 dwelling. Also in the district is a Richardsonian Romanesque style apartment building (c. 1892) and a set of vernacular post-American Civil War townhouses.It was listed on the National Register of Historic Places in 1980. In 1999, the district was encompassed by the East Wheeling Historic District.

Central Catholic High School is a parochial, Roman Catholic high school in Wheeling, West Virginia. It is part of the Roman Catholic Diocese of Wheeling-Charleston. Central Catholic High School has been educating young men and women since 1865. The school is a part of the Diocese of Wheeling-Charleston campus, which includes the Cathedral of St. Joseph, the diocesan offices, and the chancery. At the end of the 2016–2017 school year, Bishop Donahue Memorial High School closed and merged into Central Catholic.

Cathedral Parish School, also known as Wheeling Catholic Elementary and Diocese of Wheeling-Charleston Chancery, was a historic elementary school building located at Wheeling, Ohio County, West Virginia. It was built in 1896–1897, to service the St. Joseph Cathedral parish. A gymnasium addition was built in 1939. It is a three-story brick building, with an elevated first floor. It sits on a sandstone base. It features a center square tower with a pyramidal roof and Late Gothic Revival details.It was listed on the National Register of Historic Places in 1997. It is located in the East Wheeling Historic District.

The Capitol Theatre (formerly the Capitol Music Hall) is the largest theatre in West Virginia and a landmark building in the national historic district of downtown Wheeling. For many years, it has served as the home of Jamboree USA and the Wheeling Symphony Orchestra. Jamboree USA, a Saturday night live country music show broadcast on WWVA 1170 AM from 1926 until 2007, was the second-longest running radio show in the United States, second only to the Grand Ole Opry. The live music show annually drew hundreds of thousands of country music fans to Wheeling, where both local acts and nationally known celebrities such as Johnny Cash, Loretta Lynn, Merle Haggard and Charley Pride would perform.

Robert C. Woods House, also known as the Jacob S. Rhodes House, is a historic home located at Wheeling in Ohio County, West Virginia, United States. It was built between 1839 and 1845, and is a 2+1⁄2-story, 13-room brick dwelling, with an Italianate-style facade. It measures 32 feet by 90 feet, with a front block 45 feet deep and rear wing of 45 feet. The front facade features curved cast-iron lintels.Home to some of Wheeling's more prominent past business leaders,: 2  it was listed on the National Register of Historic Places on May 2, 1991. This building now serves as a clubhouse for the West Virginia Snakes Club.: 2 

West Virginia Independence Hall is a historic government building at 1528 Market Street in downtown Wheeling, West Virginia, United States. It was built in 1860 under the supervision of architect Ammi B. Young for the federal government as a custom house, post office and courthouse. It is architecturally significant for its innovative uses of wrought iron as a framing material, and is historically significant for its role in the American Civil War. It housed the Wheeling Convention (1861), as well as the West Virginia Constitutional Convention (1863), which resulted in the separation of Unionist West Virginia from Confederate Virginia. This made it the only state to secede from a Confederate state during the war. The building was originally built as the custom house for the Western District of Virginia, and later became the center of government for the Restored Government of Virginia from 1861 to 1863, with Francis H. Pierpont serving as its governor. It was declared a National Historic Landmark in 1988. The building is now a state-run museum, housing exhibits on West Virginia history.

The Wheeling Tunnel is a set of twin tunnels named for and located in Wheeling, West Virginia. The tunnels are 0.27 miles (430 m) long each, cutting through Wheeling Hill, and each carries two lanes of Interstate 70 and U.S. Route 250. The tunnels originally took three years to construct, costing $6.9 million. Reconstruction of the tunnel, originally planned to take a total of 6 months, took over three years to complete between 2007 and 2010, at a cost of $13.7 million.

The Riverside Iron Works Office Building is a historic commercial building at 1507–09 Main Street in Wheeling, West Virginia. It is a four-story masonry structure, triangular in shape, and built out of light-colored brick with stone trim elements. The first three floors, built in 1896, are Richardsonian Romanesque in style, with rusticated stone elements on the ground floor at the rounded corner, and round-arch settings for doors and windows. The fourth floor, simpler in style, was added about 1907. It was built for the Riverside Iron Works, Wheeling's leading steel manufacturers at the time, and served as its headquarters until 1898, when the company was acquired by National Tube Company. In form, it is a flatiron building. The building was listed on the National Register of Historic Places for Ohio County in 2015.

The L. S. Good House or Good Mansion is a historic home located in Wheeling, Ohio County, West Virginia. It was built in 1904 and was placed in the National Register singularly on November 28, 1988, and as part of the East Wheeling Historic District on November 22, 1999.