Russell Investments Center

Qualtrics Tower, formerly known as 2+U and 2&U, is a high-rise office building in Downtown Seattle, Washington. The 500-foot-tall (150 m), 38-story tower is located at 2nd Avenue and University Street and was completed in 2020. The building has 725,000 square feet (67,400 m2) of leasable space, including retail and public spaces on the lower levels. The largest office tenant is Qualtrics, who also hold the naming rights to the building.

Benaroya Hall is the home of the Seattle Symphony in Downtown Seattle, Washington, United States. It features two auditoria, the S. Mark Taper Foundation Auditorium, a 2500-seat performance venue, as well as the Illsley Ball Nordstrom Recital Hall, which seats 536. Opened in September 1998 at a cost of $120 million, Benaroya quickly became noted for its technology-infused acoustics designed by Cyril Harris, touches of luxury and prominent location in a complex thoroughly integrated into the downtown area. Benaroya occupies an entire city block in the center of the city and has helped double the Seattle Symphony's budget and number of performances. The lobby of the hall features a large contribution of glass art, such as one given the title Crystal Cascade, by world-renowned artist Dale Chihuly.Benaroya Hall is named for noted philanthropist Jack Benaroya, whose $15.8 million donation was the first and largest of many for construction of the facility.The hall was designed by LMN Architects of Seattle, and was awarded the National Honor Award from the American Institute of Architects in 2001. The structural engineer on the project was Magnusson Klemencic Associates. The building sits directly above the Great Northern Tunnel, which carries the primary rail corridor through the city, and adjacent to the Downtown Seattle Transit Tunnel, which has a station directly integrated into the building. The performance hall is insulated from the rumbles of the traffic in these tunnels and the streets outside the hall by floating on rubber pads which insulate it from the outer shell of the building. These same noise-insulation features would also serve to dampen the destructive effects of any prospective earthquakes.

The Diller Hotel is a former hotel building in downtown Seattle, Washington. In the early 1900s, it was known as one of Seattle's few luxury hotels. This historic building is located at the corner of First Avenue and University Street, across from the Seattle Art Museum, and is one of the few remaining buildings left from the 1890s, a period of reconstruction and commercial development after the area was destroyed by the fire of 1889. The hotel was owned by Leonard Diller (1839–1901) and family and was designed by architect Louis L. Mendel. The building is now home to The Diller Room, a craft cocktail bar housed in the former hotel lobby.

The Garden of Remembrance is a memorial in honor of over 8,000 Washington state residents who have died in wars since World War II. The memorial includes a passage from Laurence Binyon's poem, "For the Fallen". Designed by Robert Murase, the Garden is located on the Second Street side of Benaroya Hall.

The Seattle Art Museum (commonly known as SAM) is an art museum located in Seattle, Washington, United States. It operates three major facilities: its main museum in downtown Seattle; the Seattle Asian Art Museum (SAAM) in Volunteer Park on Capitol Hill, and Olympic Sculpture Park on the central Seattle waterfront, which opened in January 2007.

1201 Third Avenue (formerly Washington Mutual Tower) is a 235.31-meter (772.0 ft), 55-story skyscraper in Downtown Seattle, in the U.S. state of Washington. It is the third-tallest building in the city, the eighth-tallest on the West Coast of the United States, and the 97th-tallest in the United States. Developed by Wright Runstad & Company, construction began in 1986 and finished in 1988. 1201 Third Avenue was designed by Kohn Pedersen Fox Associates and The McKinley Architects. The building was the world headquarters of the financial company Washington Mutual from the building's opening until 2006, when the company moved across the street to the WaMu Center (renamed the Russell Investments Center after the bank collapsed in 2008).

University Street station is a light rail station that is part of the Downtown Seattle Transit Tunnel in Seattle, Washington, United States. The station is located under 3rd Avenue at University Street, near Benaroya Hall, and is served by Sound Transit's Line 1. It is located between Westlake and Pioneer Square stations and has surface connections to buses operated by King County Metro and other providers. The station consists of two side platforms situated under street level, with two mezzanines connecting to the surface. It was designed in the style of high-tech architecture and includes several pieces of public art added during construction and later additions. Trains serve the station twenty hours a day on most days and the headway between light rail trains is six minutes during peak periods, with less frequent service at other times. The transit tunnel opened on September 15, 1990, and was used exclusively by buses until 2009. Along with all other stations in the transit tunnel, University Street station was closed from 2005 to 2007 for a major renovation to accommodate light rail. Link light rail service to the station began on July 18, 2009, and bus service ceased on March 23, 2019. It is planned to be renamed to Symphony station in 2023, coinciding with the opening of Line 2.

Downtown is the central business district of Seattle, Washington. It is fairly compact compared with other city centers on the U.S. West Coast due to its geographical situation, being hemmed in on the north and east by hills, on the west by Elliott Bay, and on the south by reclaimed land that was once tidal flats. It is bounded on the north by Denny Way, beyond which are Lower Queen Anne (sometimes known as "Uptown"), Seattle Center, and South Lake Union; on the east by Interstate 5, beyond which is Capitol Hill to the northeast and Central District to the east; on the south by S Dearborn Street, beyond which is Sodo; and on the west by Elliott Bay, a part of Puget Sound.

The Triple Door is a dinner theater, lounge and music venue founded in the fall of 2003, located at 216 Union Street in Seattle, Washington. The building often hosts concerts for folk, indie, and World music groups. The Triple Door is also notable for the numerous effective fundraisers it has held and/or hosted, such as the Starlight Starbright Children's Foundation and The Triple Door Young Artists Fundraiser. One fundraiser had an auction that raised around 1.15 million dollars for various children organizations.

The Colonial Hotel is a historic building in Seattle located at 1119-1123 at the southwest corner of 1st Avenue and Seneca Streets in the city's central business district. The majority of the building recognizable today was constructed in 1901 over a previous building built in 1892-3 that was never completed to its full plans. Built as a response to the boom created by the Yukon Gold Rush, the Colonial operated as a single resident occupancy hotel into the 1970s and in the 1980s it was restored into apartments and connected to its southern neighbor, the Grand Pacific Hotel. Both were listed on the National Register of Historic Places in 1982 and later became Seattle city landmarks. Today they are known collectively as the Colonial Grand Pacific.

The Main Seattle Post Office has a significant history.

Dendreon is a biotechnology company. Its lead product, Provenge (known generically as sipuleucel-T), is an immunotherapy for prostate cancer. It consists of a mixture of the patient's own blood cells (autologous, with dendritic cells thought to be the most important) that have been incubated with the Dendreon PAP-GM-CSF fusion protein. Phase III clinical trial results demonstrating a survival benefit for prostate cancer patients receiving the drug were presented at the AUA meeting on April 28, 2009. After going through the approval process, Provenge was given full approval by the FDA on April 29, 2010. Dendreon's stock value fell 66% on August 4, 2011, after abandoning its forecast for its debut drug Provenge.In November 2014, Dendreon filed for Chapter 11 bankruptcy protection and shortly afterwards announced that it had reached agreements on the terms of a financial restructuring with certain bond holders.On February 20, 2015, Valeant Pharmaceuticals received approval to purchase all Dendreon assets. On January 9, 2017 Sanpower Group agrees to acquire Dendreon from Valeant for $819.9 million In June 2017, Sanpower Group, a Chinese conglomerate, purchased Dendreon from Valeant for $820 million.