Clarksdale Housing Complex

St. Boniface Catholic Church (also known as St. Bonifacius Kirche Complex) is a historic church at 501-531 E. Liberty Street in Louisville, Kentucky. Established in 1836, St. Boniface was the first German Catholic parish in the city. It is also the oldest, continuously existent, Catholic parish in the city of Louisville. The present structure was built in 1899 and added to the National Register in 1982 as St.Bonifacius Kirche Complex.

University of Louisville Hospital is a non-profit, teaching hospital located in downtown Louisville, Kentucky and is owned and operated by UofL Health.

Phoenix Hill is a neighborhood of Louisville, Kentucky just east of Downtown. Its boundaries are Market Street to the North, Preston Street to the West, Broadway to the South, and Baxter Avenue to the East. The Phoenix Hill neighborhood, settled before 1850 by German immigrants, is now a rich tapestry of people and a diverse mix of business, industry and residences. It is a neighborhood of mixed but compatible uses. Much of the residential part of the neighborhood is included in the National Historic District. The neighborhood includes: a large medical district, a thriving arts district, a thriving entertainment district, social service agencies and agencies that serve the homeless, small family businesses and larger industry, single-family homes, market-rate apartment complexes and subsidized housing complexes, and new and historic churches.

The East Market District, colloquially referred to as NuLu (a portmanteau of "New" and "Louisville"), is an unofficial district of Louisville, Kentucky, situated along Market Street between downtown to the west, Butchertown to the north, Phoenix Hill to the south, and Irish Hill to the east. The area is home to schools, churches, large and small businesses and some of the city's oldest homes and businesses. A destination since Louisville's founding, Market Street has played host to a variety of businesses throughout the city's history that have drawn Louisvillians for generations to its addresses. The district is today well known for its galleries showcasing local, regional and national artists, unique specialty stores, antique shops and a growing number of upscale restaurants. While multiple art galleries are located in Louisville, they are especially concentrated in this district. Keeping with the sustainable culture of NuLu, many of its restaurants offer organic and locally sourced ingredients. The district also houses numerous architecture firms, antique stores, advertising and media agencies, a record label, film production group, publishing company, designers and more.

Thomas Edison House is a historic house located in the Butchertown neighborhood of Louisville, Kentucky. The house is a shotgun duplex built around 1850. Thomas Edison took up residence in the same neighborhood, possibly even at this location, a part of the time he lived in Louisville from 1866 to 1867. The house features a museum that honors Edison and his inventions.

St. Martin of Tours Catholic Church is a Roman Catholic parish church in Louisville, Kentucky. It is the fourth parish in the city and one of the oldest in the Archdiocese of Louisville. Founded as a church for German immigrants on the east side of Louisville in 1853, the church building was completed and dedicated on August 20, 1854. Expanded in the 1860s and renovated in the 1890s, the church building remains one of the oldest large structures and one of the few remaining antebellum public buildings in Louisville.

Louisville Slugger Field is a baseball stadium in Louisville, Kentucky. The baseball-specific stadium opened in 2000 with a seating capacity of 13,131. It is currently home to the professional baseball team, the Louisville Bats, Triple-A affiliate of the Cincinnati Reds. From 2015 to 2019, it was also home to Louisville City FC, a professional soccer team in the USL Championship. The unique design of Louisville Slugger Field includes a former train shed on the site which was incorporated into the stadium. The Ohio River and state of Indiana are visible from the park, as well as views of downtown Louisville. Naming rights for the stadium were purchased by Hillerich & Bradsby, makers of the famous Louisville Slugger baseball bat, and the Louisville Slugger Museum & Factory is located several blocks further down Main Street. The stadium is accessible from I-64, I-65, and I-71.

The David Armstrong Extreme Park, formerly called the Louisville Extreme Park, is a 40,000 square foot (3,700 m2) public skatepark located near downtown Louisville, Kentucky, United States, in the Butchertown neighborhood. It opened on April 5, 2002, and gained national recognition after the release of Tony Hawk's Gigantic Skatepark Tour, in which the park was featured. The park was designed with the input of a local task force. The public skatepark is owned by Louisville Metro Government and operated by Metro Parks. In 2014, about one-third of the park was demolished, to be followed by the rebuilding of facilities on adjacent property, to make way for flyover ramps to support the new Abraham Lincoln Bridge. The rebuild was completed on April 14, 2015, where the park was dedicated in former Louisville Mayor David L. Armstrong's honor.In 2023, it was announced that the park would be closing at 11PM every night, transitioning to a limited operating schedule for the first time since the park opened. This was a response to a rise in criminal activity and increased need for police presence at the park during late-night hours. At this time, several cameras were installed to enforce the curfew, and better monitor the park during operating hours.

On April 10, 2023, a mass shooting occurred at the Old National Bank in Louisville, Kentucky, United States. Five people were killed, and eight others were injured, including two responding police officers. The shooter, 25-year-old former employee Connor James Sturgeon, was fatally shot by police.

The University of Louisville School of Medicine at the University of Louisville is a medical school located in Louisville, Kentucky, United States. Opened as the Louisville Medical Institute in 1837, it is one of the oldest medical schools in North America and the 9th oldest in the United States.University of Louisville researchers achieved the first implantation of the first fully self-contained artificial heart, the first successful hand transplant in the world, the first five hand transplants in the United States and nine hand transplants in eight recipients as of 2008, the first discovery of embryonic-like stem cells in adult human bone marrow, and the first proof that adult nasal stem cells can grow to become other types of cells. In 2013, U.S. News & World Report ranked the University of Louisville School of Medicine #76 in research in its annual list of Best Medical Schools in the United States.The school offers several dual degree programs including MD/MS, MD/MA, MD/MBA, MD/MPH, and MD/PhD degrees. For the 2017 entering class, 162 students enrolled in the Doctor of Medicine (M.D.) program. In May 2013, Dr. Toni M. Ganzel was selected as the next dean of the School of Medicine.

Kentucky's 3rd congressional district is a congressional district in the U.S. state of Kentucky. It encompasses almost all of Louisville Metro, which, since the merger of 2003, is consolidated with Jefferson County, though other incorporated cities exist within the county, such as Shively and St. Matthews. The far eastern portions of Louisville Metro are part of the 2nd congressional district. The district is currently represented by Democrat Morgan McGarvey. With a Cook Partisan Voting Index rating of D+9, it is the only Democratic district in Kentucky.

Norton Children's Hospital, formerly Kosair Children's Hospital, is a pediatric acute care children's hospital located in Louisville, Kentucky and affiliated with the University of Louisville School of Medicine. The hospital has 300 pediatric beds, providing comprehensive pediatric specialties and subspecialties to infants, children, teens, young adults, age 0-21 throughout Kentucky and the surrounding states. Established in 1892 as Children's Free Hospital, it is part of Norton Healthcare. Norton Children's Hospital also features the region's only Level 1 Pediatric Trauma Center and Level IV Neonatal Intensive Care Unit. In 2016, actress Jennifer Lawrence, a Louisville native, donated $2 million to the Norton Children's Hospital in Louisville to set up a cardiac intensive care unit (CICU) named after her foundation.