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The Overland Park Convention Center, opened in 2002 and hosts on average 330 events each year. The OPCC sits on a 26-acre (110,000 m2) site in Overland Park, the largest suburb in the Kansas City, Missouri metropolitan area and the second largest city in Kansas. The mid-sized convention center features a 60,000-square-foot (5,600 m2) exhibition hall that connects to the 25,000 sq ft (2,300 m2). Edwin C. Eilert Ballroom. The OPCC provides an additional 15,000 sq ft (1,400 m2). of event space of divisible meeting rooms, and 40,000 sq ft (3,700 m2). of pre-function space that proudly houses over 50 selected works of art created by renowned Midwestern artists. OPCC was designed by architectural firm DLR Group. Major partners include Pepsi, Fern Exposition, Fiorella's Jack Stack Barbecue.

Shawnee Mission South High School is a high school located in Overland Park, Kansas, United States, serving students in grades 9-12. The school is one of several public high schools located within Shawnee Mission and operated by Shawnee Mission USD 512 school district. The school colors are green and gold and the school mascot is the Raider. The average annual enrollment is approximately 1,600 students. The school newspaper is called The Patriot.

The Sprint World Headquarters Campus is a collection of 17 buildings encompassing 3,900,000-square-foot (360,000 m2) on 200 acres in Overland Park, Kansas that formerly housed the world headquarters of Sprint Corporation, an American telecom company. The buildings were designed by Hillier Architecture (which became RMJM in 2007) based on a theme which Sprint dubbed the "University of Excellence." RMJM had also designed the Basking Ridge, New Jersey headquarters campus of the AT&T Corporation (now the headquarters of Verizon Wireless). The first buildings opened in 1997 as Sprint consolidated operations in 50 buildings in the Kansas City metropolitan area. Most of the buildings are four and five stories tall with the tallest structure being a 175-foot (53 m) clock tower. Included on the campus are an amphitheater for 3,000 people; parking garages for 12,500 cars; athletic fields, and hiking and biking trails with 6,000 trees that connect to public trails outside the campus. 60 percent of the land area was left green. At the time a Sprint official said Sprint opted for a low rise building rather than a tall structure because "communication doesn't happen as well when offices are vertical instead of horizontal." When it was built it was described as the largest office complex in the Midwest.The building was enabled in 1989 when Overland Park gave the company a property tax abatement that called for 50 percent property tax abatement for 10 years and the remaining 50 percent paid initially over 20 years. Overland Park issued $1 billion in revenue bonds in 1997. The abatement expired in 2013.The campus was designed to accommodate 14,500 employees and it reached its maximum capacity at the time of the Nextel-Sprint merger in 2004. Since then Sprint has been downsizing with 11,000 employees (7,300 Sprint employees, the rest contractors) in the complex in 2010. The headquarters for the merged company was consolidated in the building in 2008 when staff moved from Reston, Virginia.In 2009 Sprint began subleasing portions of the complex allocating 800,000 square feet (74,000 m2) to other companies starting with Sprint spin off Embarq (it eventually moved its headquarters to a different building outside the complex) Other subtenants include JPMorgan Retirement Plan Services which moved 800 employees to the complex from its offices on Ward Parkway in December 2009.Other companies in the complex are Apria and CareCentrix with call centers there. KeyBank Real Estate Capital is also moving to the complex. Sprint has announced plans to rebrand the campus including renaming a street from Sprint Parkway to Outlook to accommodate JPMorgan and rebrand the name on the entrances.

Hyman Brand Hebrew Academy is a K-12 community Jewish Day School located on the Jewish Community Campus in Overland Park, Kansas. A private school offering Judaic instruction along with a college-preparatory secular education, HBHA serves about 230-250 students from diverse reform through orthodox backgrounds. A 2005 Blue Ribbon Kansas School, Hyman Brand Hebrew Academy celebrated its 50th anniversary in the 2015–16 school year.

Menorah Medical Center is an acute care hospital located in Overland Park, Kansas at 5721 West 119th Street. It is part of the HCA Midwest Division.

Saint Paul School of Theology (SPST) is a United Methodist seminary in Leawood, Kansas, United States. In addition to the Kansas City area campus at Church of the Resurrection, Saint Paul School of Theology at Oklahoma City University has been offering courses since September 2008. The Oklahoma campus works in a collaboration with Oklahoma City University in Oklahoma City, Oklahoma. Additionally, the Kansas Campus works in partnership with the United Methodist Church of the Resurrection to serve the Greater Kansas City Metro Area in Leawood, KS. The student body has almost equal numbers of men and women, representing many states and other countries. While most students are United Methodist, several other denominations are represented in the student body each year.

Town Center Plaza is an open-air shopping center in Leawood, Kansas, United States. It is home to a number of upscale stores with few or no other locations in the Kansas City area, including Allen Edmonds, Arhaus, Brooks Brothers, Bonobos, Crate & Barrel, L.L. Bean, Peloton, Purple Mattress, a Restoration Hardware Gallery store, and Sundance. It opened in 1996 with Jacobson's as the main anchor store. After Jacobson's closed in 2002, it was converted to The Jones Store in 2003 and Macy's in 2006. Another original tenant was Galyan's, which became Dick's Sporting Goods in 2004. It and nearby Town Center Crossing (formerly One Nineteen) are owned by Washington Prime Group, formerly WP Glimcher and before that, Glimcher Realty Trust, who bought Town Center Plaza from DDR Corp. for $139 million.

Blue Valley North High School is a public high school located in Overland Park, Kansas, United States, serving students in grades 9–12. The school is one of the five high schools operated by Blue Valley USD 229 school district. The school colors are navy blue and silver. The current enrollment is approximately 1,550 students. The principal is Tyson Ostroski.Blue Valley North is a member of the Kansas State High School Activities Association and offers a variety of sports programs. Athletic teams compete in the 6A Division and are known as the "Mustangs". Extracurricular activities are also offered in the form of performing arts, school publications, and clubs.

Cleveland University-Kansas City (CUKC) is a private university in Overland Park, Kansas, United States. Cleveland University-Kansas City is known primarily for its chiropractic doctorate program (D.C.) but it also offers associate, bachelor's, and master's degrees. The university has been in operation in the Kansas City area since 1922 and has occupied its current 34-acre Overland Park, Kansas, location since 2008.

The Temple, Congregation B'nai Jehudah is the oldest and largest synagogue in the greater Kansas City metropolitan area. Established in 1870 in Kansas City, Missouri, it was a founding member of the Union for Reform Judaism. Its fourth building, designed by Kivett and Myers architects, was a modernist structure that was "striking for its exterior profile and massing and its combination of natural and industrial forms to create an appearance rooted in both primeval nature and futuristic design." Completed in 1969, it was demolished after the congregation relocated to Overland Park, Kansas in 2000. The senior rabbi is Arthur P. Nemitoff, the rabbi is Sarah Smiley, and the rabbi emeritus is Michael R. Zedek.

Metcalf South Shopping Center was a shopping mall in Overland Park, Kansas. It opened in 1967, near a large, unique department store called the French Market, which later became a strip mall anchored by Kmart and Hancock Fabrics (the Kmart closed in late 2013 and Hancock announced a move in early 2014). The Metcalf South mall itself originally featured two main floors of retail space, although later a third floor of retail space was added, which in recent years became home to office space. It featured two anchor stores (Sears and the Jones Store Company), later taken over by Macy's. Sears and the Glenwood Arts movie theater remained open in later years, while Macy's announced the closure of its Metcalf South store in January 2014.After more than a decade of decline that left Metcalf South a dead mall, the property was purchased in February 2014 by Lane4 Property Group and The Kroenke Group, and the owner of Lane4 stated it is likely the mall will be razed. On September 19, 2014, Metcalf South Mall closed. The movie theater closed on January 25, 2015. In 2015, Sears Holdings spun off 235 of its properties, including the Sears at Metcalf South Shopping Center, into Seritage Growth Properties.Demolition of the Metcalf South Mall (except for Sears) began on April 21, 2017. Sears started the Store Closing sale on June 30, 2017 and closed September 17, 2017. As of July 2019, a brand new Lowe's occupies the space that Glenwood Arts and Macy's held at Metcalf South Mall. The old Sears store, however, is still standing. A new ice cream parlor Andy's Frozen Custard opened in July of 2019. In 2020 construction on Longhorn Steakhouse began. In Early 2021 Longhorn Stakehouse opened to the public the same year Everest Bank completed construction. New construction on an unknown business

Saint Luke's South Hospital is a 171-bed hospital located in Overland Park, Kansas.