Central New York Telephone and Telegraph Building

St. Paul's Cathedral in Syracuse, New York was designed by Henry Dudley, who worked with Frank Wills until Wills' early death in 1857.The church is located at 310 Montgomery Street in downtown Syracuse.

The Hills Building is a high-rise office building located in Syracuse, New York.

The Carnegie Building in Syracuse, New York, previously known as the Syracuse Public Library, is a historic Carnegie library on Montgomery Street at Jefferson Circle in downtown Syracuse. It was built by the City of Syracuse in 1905-06, and came into County of Onondaga ownership in 1976. The building served as a library for 83 years and was the main library of the Syracuse Public Library system, which merged with Onondaga County's library system in 1976 to become the Onondaga County Public Library System. As "Carnegie Library", it was listed on the National Register of Historic Places as a contributing building in the Montgomery Street–Columbus Circle Historic District in 1980. Following acquisition and renovation by the Carnegie Redevelopment Corp., a local development corporation, the building was leased by the Syracuse city school district for 15 years, from 1996 - 2012 when the school district chose not to renew its lease option. In 2019, after it had sat vacant for eight years, a proposal was floated to renovate it for $4.1 million to hold city and county planning and economic development offices and save on the city's rental costs. The plan was approved in 2021 and work began in 2022, but its current status is unknown as of July 2024.

The Montgomery Street–Columbus Circle Historic District is located in Syracuse, New York. It was added to the National Register of Historic Places in 1980.

Columbus Circle is a neighborhood and plaza in the downtown section of Syracuse, New York, United States. At the center of the circle is a large fountain and the Columbus Monument, designed by the Syracuse-born architect Dwight James Baum and dedicated in 1934. Columbus Circle is home to Syracuse's two cathedrals, the Episcopalian St. Paul's Cathedral and the Roman Catholic Cathedral of the Immaculate Conception, as well as the Onondaga County Courthouse and the John H. Mulroy Civic Center. The circle, originally known as Library Circle and later as St. Mary's Circle, began as a chiefly residential district. Beginning in the early 20th century it slowly developed as government and commercial buildings were constructed. From 1913 to 1933 the circle played host to the cities annual tree lighting. After the Columbus Monument's dedication in 1934, it was the site of annual memorial services on Columbus Day as well as protests advocating for its removal. In October 2020 the city of Syracuse announced plans to remove the statue of Christopher Columbus and redevelop the circle into "Heritage Park." The removal was halted by a court decision in 2022, which the city successfully appealed.

The Cathedral of the Immaculate Conception in Syracuse, New York is the mother church of the Roman Catholic Diocese of Syracuse. It is the seat of the Bishop of Syracuse, currently Douglas Lucia.

Courier Building, also known as the Frazee Block, Cutlery Block, Fire Engineer Block, and Potter Building, is a historic commercial building located in Downtown Syracuse, Onondaga County, New York. It was built in 1844, and is a four-story, trapezoidal shaped, Greek Revival style painted brick building. It was updated in 1918 with Chicago Commercial style design elements when modified for use as a Moose Lodge (1918-1946). The Courier newspaper occupied the building from 1856 to 1905. It was the site of Daniel Webster's 1851 "Syracuse Speech" in which he equated resistance to the Fugitive Slave Law with treason. In response, crowds in the area freed an escaped slave from the custody of federal marshals, galvanizing opposition to slavery in Central New York.: 5, 11–12 It was listed on the National Register of Historic Places in 2014.

Downtown Syracuse is the economic center of Syracuse, New York, and Central New York, employing over 30,000 people, and housing over 4,300. It is also one of the 26 officially recognized neighborhoods of Syracuse.

The Syracuse City Hall is the city hall of Syracuse, New York. Unusually for civic buildings in the United States, it was constructed from 1889 to 1893 in the Romanesque Revival architectural style. The bid accepted for the construction was for $238,750.00 from Hughes Brothers of Syracuse.

The Diocese of Syracuse (Latin: Diœcesis Syracusensis) is a Latin Church ecclesiastical territory, or diocese, of the Catholic Church in Upstate New York in the United States. Its episcopal see is located in Syracuse. It is a suffragan diocese in the ecclesiastical province of the metropolitan Archdiocese of New York. On June 4, 2019, Pope Francis appointed Douglas Lucia to be the next Bishop of Syracuse. Lucia was consecrated to the episcopacy and installed as bishop on August 8, 2019.

The Erie Canal Museum is a historical museum about the Erie Canal located in Syracuse, New York. The museum was founded in 1962 and is a private, non-profit corporation. It is housed in the Syracuse Weighlock Building dating from 1850. The Syracuse Weighlock Building was in operation as a weighlock from 1850 to 1883. In 1883 the canal decided to stop charging tolls. The weighlock building was essentially used as a big, elaborate scale to weigh the boats traveling on the Erie Canal and determine how much each boat would pay for a toll. Today the museum includes not only artifacts from the Erie Canal, but also a gallery of present canal life. It is the mission of the museum to help people to learn the rich history of the Erie Canal and that it is not just a thing of the past, but still very much exists today in different forms. The museum's Weighlock Building was listed on the National Register of Historic Places in 1971.

The State Tower Building is a high-rise building located in Syracuse, New York. Completed in 1928, the building remains the highest in Syracuse. It has around 23 floors and is around 312 feet (95 meters) tall. For several years after the Bastable Theatre burnt down in a 1923 fire, the plot of land was considered as the potential site of a new theatre or an office building. Eventually the plot's owners, Central Offices decided to build an office building. Designed by Thompson & Churchill, work began on the foundation of the State Tower Building in 1927. The tower was completed by late April 1928. It initially functioned as an office building, and was listed on the National Register of Historic Places as a contributing property in the Hanover Square Historic District. In 2016 the building was bought by different owners, who redeveloped the top floors into high-end apartments; retaining just the first eight floors as office space.