Robert M. and Matilda (Kitch) Grindley House

The League of Catholic Women Building is located at 100 Parsons Street in Midtown Detroit, Michigan. It is also known as Casgrain Hall or the Activities Building. The building was listed on the National Register of Historic Places in 1997.

Sts. Peter and Paul Academy is a Catholic school building located at 64 Parsons Street in Midtown Detroit, Michigan. It currently serves as the St. Patrick Senior Center. It was listed on the National Register of Historic Places in 1997.

The Detroit School of Arts (DSA), originally known as the Detroit High School for the Fine and Performing Arts, is a public, magnet high school located in Midtown Detroit, Michigan.The Detroit School of Arts is a part of the Detroit Public Schools district. Entrance to Detroit School of Arts is based on an audition that takes place at the end of a student's eighth grade year. Students are required to declare a major of study i.e. Dance, Theatre, Instrumental Music, etc. It is one of four magnet schools in Detroit, where the others are Renaissance High School, Cass Technical High School and Communication & Media Arts High School. Entrance is based on test scores and middle school grades.

The Chapel of St. Theresa–the Little Flower was a church located at 58 Parsons Street in Midtown Detroit, Michigan. It was later known as St. Patrick Church. The building was listed on the National Register of Historic Places in 1997, and demolished in September 2023.

The Architects Building is an office building located at 415 Brainard Street in Midtown Detroit, Michigan. It was listed on the National Register of Historic Places in 1995.

The Cass–Davenport Historic District is a historic district containing four apartment buildings in Detroit, Michigan, roughly bounded by Cass Avenue, Davenport Street, and Martin Luther King, Jr. Boulevard. The district was listed on the National Register of Historic Places in 1997. The Milner Arms Apartments (originally known as the Hotel Stevenson) abuts, but is not within, the district.

The Milner Arms Apartments, originally known as the Hotel Stevenson, is a high rise building located at 40 Davenport Street in Midtown Detroit, Michigan; it was listed on the National Register of Historic Places in 1997. It is adjacent to, but not part of, the Cass-Davenport Historic District.

The Detroit–Columbia Central Office Building is a building located at 52 Selden Street in Midtown Detroit, Michigan. It is also known as the Michigan Bell Telephone Exchange. The building was listed on the National Register of Historic Places in 1997.

Orchestra Hall is an elaborate concert hall in the United States, located at 3711 Woodward Avenue in Midtown Detroit, Michigan. The hall is renowned for its superior acoustic properties and serves as the home of the internationally known Detroit Symphony Orchestra (DSO), the fourth oldest orchestra in the United States. With the creation of an adjoining auditorium for jazz and chamber music in 2003, Orchestra Hall became part of the Max M. and Marjorie S. Fisher Music Center. It was listed on the National Register of Historic Places in 1971.

The University of Michigan Detroit Center (UMDC, U-M Detroit Center or Detroit Center) is a community outreach center, meeting/events facility, and academic home base for University of Michigan units, located in Midtown Detroit. The facility serves as a home base to more than 50 university staff and faculty members from the campuses of the University of Michigan and University of Michigan-Dearborn. Providing a visible symbol of the nearly 200-year relationship between the City of Detroit and the University of Michigan, the U-M Detroit Center serves as a gateway for University and urban communities to take advantage of each other’s learning, research and cultural activities. The mission of the University of Michigan Detroit Center is to mutually enrich University and Detroit communities through service, education, research and the exchange of culture.

The Cass Community United Methodist Church is located at 3901 Cass Avenue in Midtown Detroit, Michigan. It was built in 1883 as the Cass Avenue Methodist Episcopal Church, listed on the National Register of Historic Places in 1982, and designated a Michigan State Historic Site in 1985.

The Professional Plaza Tower, also known as the 'Hammer and Nail' building due to its two iconic illuminated signs (now removed), is a high-rise building located at 3800 Woodward Avenue in Midtown Detroit, Michigan. It was listed on the National Register of Historic Places in 2016.