House at 113–115 Center Street

13 Annis Street is a historic mill worker house in Methuen, Massachusetts. Built about 1880, it is a typical small residence built for workers at the nearby Arlington Mills. It was added to the National Register of Historic Places in 1984, but has lost many of its exterior decorative details since.

Henry C. Nevins Home for Aged and Incurables was built in 1906 in Methuen, Massachusetts. It was listed on the National Register of Historic Places in 1984. It and the Nevins Memorial Library, located at 305 Broadway were built by for Henry C. Nevins and his family as a memorial to his father, David C. Nevins, Sr. Both buildings were listed on the National Register on the same day.

The Urias Hardy House is a historic house at 50 Brown Street in Methuen, Massachusetts.

The Arlington Mills Historic District encompasses a major 19th century textile manufacturing complex in Lawrence and Methuen, Massachusetts. Developed between 1865 and 1925, it was one of the state's largest textile operations at its height. At the time of its listing on the National Register of Historic Places in 1985, the mill complex was owned by Malden Mills.

The House at 23 East Street in Methuen, Massachusetts is a well preserved Greek Revival cottage. Built in c. 1840, it is a 1+1⁄2-story three bay wood-frame structure with a side hall entry and a front-facing gable end. The main entrance is flanked by full-length sidelight windows and topped by a transom window. Houses similar to this were generally occupied by craftsmen such as boot-, shoe-, and hatmakers. Before large-scale industrialization they were scattered throughout the town.The house was listed on the National Register of Historic Places in 1984.

Methuen Memorial Music Hall, initially named Serlo Organ Hall, was built by Edward Francis Searles to house "The Great Organ", a very large pipe organ that had been built for the Boston Music Hall. The hall was completed in 1909, and stands at 192 Broadway in Methuen, Massachusetts.

Presentation of Mary Academy, commonly abbreviated PMA was a private Roman Catholic co-ed high school, grades 9–12 in Methuen, Massachusetts. It was located in the Roman Catholic Archdiocese of Boston. PMA's student body hailed from 31 local cities and towns, represented 3 New England states, and 4 countries.

The Lawrence Street Cemetery, or more commonly known as "the Village Burying Ground", is a historic cemetery on Lawrence Street in Methuen, Massachusetts. Methuen's third oldest cemetery, it was founded in 1832 when the center of town was shifted west from Meeting House Hill to Gaunt Square. Late in the 19th century, wealthy industrialist Edward Searles built the 8 foot granite wall on the sides facing his estate. In the cemetery rests Searles siblings, parents and wife Mary Hopkins Searles.The cemetery was listed on the National Register of Historic Places in 1984.

House at 9 Park Street is a historic house in Methuen, Massachusetts. According to the assessor's records the house at 9 Park Street was built in 1876 at a value of $950. A notice in the Methuen Transcript says local builder Albert Fales built an addition in 1880. according to an 1885 directory, the first owner was John W. Mann of Tompkins and Mann (paint and oil vendors), 191 Essex Street, Lawrence, Massachusetts. Mrs. Mann still occupied the house as of 1906.It was added to the National Register of Historic Places in 1984.

The George A. Waldo House is a historic house in Methuen, Massachusetts. Built in 1825 and altered somewhat around 1900 by local philanthropist Edward Searles, it is one of Methuen's finest examples of Federal period architecture. It was added to the National Register of Historic Places in 1984, and is currently occupied by the Kenneth H. Pollard Funeral Home.

10 Park Street (also known as the E.M. Clark House) is a historic house located in Methuen, Massachusetts. The house was added to the National Register of Historic Places on January 20, 1984.

The Henry Preston House is a historic house in Methuen, Massachusetts. Built around 1840, the house was originally built as a one-story house belonging to Henry Preston who had a wheelwright shop next door. Assessor's records indicate that in the 1850s, the house belonged to Enoch A. Merrill, and in 1875 the estate of Enoch A. Merrill was taxed to Joel Foster. The barn, which still exists, appears of the map between 1872 and 1884. Foster, who owned other farm sites in Methuen, was named the leading farmer in Essex County in 1884.It was added to the National Register of Historic Places as the House at 15–19 Park Street in 1984.