First National Bank (Lewiston, Maine)

The Union Block is a historic commercial building at 21-29 Lisbon Street in downtown Lewiston, Maine. Built in 1870, it is a good local example of commercial Italianate architecture, built during a significant period of the city's growth. It was listed on the National Register of Historic Places in 1986.

The Lewiston Trust and Safe Deposit Company is a historic commercial building at 46 Lisbon Street in Lewiston, Maine. Built in 1898, it is one of the least-altered designs of the important local architectural firm Coombs, Gibbs & Wilkinson. Its only significant alterations were in 1926 and the 1940s, when it served as a retail space occupied by Grant's Clothing for many years. The building was listed on the National Register of Historic Places in 1986. It continues to house retail and other commercial tenants.

Lyceum Hall is a historic commercial building in downtown Lewiston, Maine, United States. Built in 1872, the Second Empire hall is one of the city's few surviving designs of Charles F. Douglas, a leading Maine architect of the period, and for a number of years housed the city's only performance venue. The building was listed on the National Register of Historic Places in 1986.

The Dingley Building, formerly the Oak Street School, is a historic municipal building at 36 Oak Street in Lewiston, Maine. Built in 1890, it is a distinctive local example of Richardsonian Romanesque architecture, designed by local architect George M. Coombs. It was added to the National Register of Historic Places in 1976. It now houses the Lewiston school system's administrative offices.

The Osgood Building is an historic commercial building at 129 Lisbon Street in Lewiston, Maine. Built in 1893, it is one of few known surviving commercial works by local architect Jefferson L. Coburn, and the only known use of imported English white brick in the state. The building was listed on the National Register of Historic Places in 1986.

The First McGillicuddy Block is an historic commercial building at 133 Lisbon Street in Lewiston, Maine. The block was built in 1895 by Daniel J. McGillicuddy, and is one of two surviving local examples of the work of local architect Jefferson Coburn. The block, a fine example of late Victorian architecture, was added to the National Register of Historic Places in 1986.

The Manufacturer's National Bank is an historic commercial building at 145 Lisbon Street Lewiston, Maine. Built in 1914, it was the tallest commercial building in Lewiston until 1950, and was one of the last major commercial buildings erected in the city before World War I, and one of the few that exhibits Classical Revival style. It was listed on the National Register of Historic Places in 1986.

St. Joseph's Catholic Church is a historic former church building at 257 Main Street in Lewiston, Maine. Built 1864–67, it was the first Roman Catholic church in the city, and is one of only two surviving buildings in the state designed by Patrick C. Keely. It was listed on the National Register of Historic Places in 1989. The church closed in 2009, and was in 2013 threatened with demolition. Alternative uses for the structure are still being sought.

Maine Museum of Innovation, Learning and Labor (Maine MILL) is located in the Bates Mill Historic District, in Lewiston, Androscoggin County, Maine.Maine Museum of Innovation, Learning and Labor (Maine MILL) is a history and culture museum in downtown Lewiston, Maine.

Cowan Mill (also known as the Aurora Mill or Cowan Woolen Company Mill) was a historic mill at Island Mill Street in Lewiston, Maine. The 4-story Greek Revival mill was built in 1850 on the site of Lewiston's first textile mill (built by John A. Briggs in 1836 and destroyed by fire in March 1850). David Cowan was twice elected mayor of Lewiston. The mill was added to the National Register of Historic Places in 1985. On July 15, 2009, the Mill was completely destroyed under suspicious circumstances in a massive fire. Six days later, Justice Thomas E. Delahanty II ordered the mill be destroyed due to it being unsafe. Chabot Construction Company carried out the order the same day.The mill was removed from the National Register of Historic Places on November 2, 2011.

The Lewiston Main Post Office of Lewiston, Maine is located at 49 Ash Street in downtown Lewiston. Built in 1933 and enlarged in 1975, it is a fine local example of Colonial Revival architecture. The building was listed on the National Register of Historic Places in 1986 as U.S. Post Office–Lewiston Main.

The Pilsbury Block is an historic commercial building at 200-210 Lisbon Street in Lewiston, Maine. The block was built in 1870, and is a late example of Italianate architecture, exhibiting some Romanesque details. The building was added to the National Register of Historic Places in 1983.