Lewiston Trust and Safe Deposit Company

Lyceum Hall is a historic commercial building in downtown Lewiston, Maine, United States. Built in 1872, the Second Empire hall is one of the city's few surviving designs of Charles F. Douglas, a leading Maine architect of the period, and for a number of years housed the city's only performance venue. The building was listed on the National Register of Historic Places in 1986.

The Union Block is a historic commercial building at 21-29 Lisbon Street in downtown Lewiston, Maine. Built in 1870, it is a good local example of commercial Italianate architecture, built during a significant period of the city's growth. It was listed on the National Register of Historic Places in 1986.

The First National Bank is a historic commercial building in Lewiston, Maine. Built about 1903 for the city's first chartered bank, it is a fine local example of French-inspired Classical Revival architecture. The building was listed on the National Register of Historic Places in 1986.

The Osgood Building is an historic commercial building at 129 Lisbon Street in Lewiston, Maine. Built in 1893, it is one of few known surviving commercial works by local architect Jefferson L. Coburn, and the only known use of imported English white brick in the state. The building was listed on the National Register of Historic Places in 1986.

The First McGillicuddy Block is an historic commercial building at 133 Lisbon Street in Lewiston, Maine. The block was built in 1895 by Daniel J. McGillicuddy, and is one of two surviving local examples of the work of local architect Jefferson Coburn. The block, a fine example of late Victorian architecture, was added to the National Register of Historic Places in 1986.

The Manufacturer's National Bank is an historic commercial building at 145 Lisbon Street Lewiston, Maine. Built in 1914, it was the tallest commercial building in Lewiston until 1950, and was one of the last major commercial buildings erected in the city before World War I, and one of the few that exhibits Classical Revival style. It was listed on the National Register of Historic Places in 1986.

The Dingley Building, formerly the Oak Street School, is a historic municipal building at 36 Oak Street in Lewiston, Maine. Built in 1890, it is a distinctive local example of Richardsonian Romanesque architecture, designed by local architect George M. Coombs. It was added to the National Register of Historic Places in 1976. It now houses the Lewiston school system's administrative offices.

The Pilsbury Block is an historic commercial building at 200-210 Lisbon Street in Lewiston, Maine. The block was built in 1870, and is a late example of Italianate architecture, exhibiting some Romanesque details. The building was added to the National Register of Historic Places in 1983.

The Odd Fellows Block is a historic commercial building at 182-190 Lisbon Street in Lewiston, Maine. Built in 1876, it is an important early work of Lewiston architect George M. Coombs, then in partnership with William H. Stevens. It is a significant local example of commercial Victorian Gothic architecture, which typified Lewiston's downtown of the period. The building was listed on the National Register of Historic Places in 1986.

Maine Museum of Innovation, Learning and Labor (Maine MILL) is located in the Bates Mill Historic District, in Lewiston, Androscoggin County, Maine.Maine Museum of Innovation, Learning and Labor (Maine MILL) is a history and culture museum in downtown Lewiston, Maine.

The Lewiston Main Post Office of Lewiston, Maine is located at 49 Ash Street in downtown Lewiston. Built in 1933 and enlarged in 1975, it is a fine local example of Colonial Revival architecture. The building was listed on the National Register of Historic Places in 1986 as U.S. Post Office–Lewiston Main.

St. Joseph's Catholic Church is a historic former church building at 257 Main Street in Lewiston, Maine. Built 1864–67, it was the first Roman Catholic church in the city, and is one of only two surviving buildings in the state designed by Patrick C. Keely. It was listed on the National Register of Historic Places in 1989. The church closed in 2009, and was in 2013 threatened with demolition. Alternative uses for the structure are still being sought.